19,205 research outputs found
Spare capacity allocation using shared backup path protection for dual link failures
This paper extends the spare capacity allocation (SCA) problem from single link failure [1] to dual link failures on mesh-like IP or WDM networks. The SCA problem pre-plans traffic flows with mutually disjoint one working and two backup paths using the shared backup path protection (SBPP) scheme. The aggregated spare provision matrix (SPM) is used to capture the spare capacity sharing for dual link failures. Comparing to a previous work by He and Somani [2], this method has better scalability and flexibility. The SCA problem is formulated in a non-linear integer programming model and partitioned into two sequential linear sub-models: one finds all primary backup paths first, and the other finds all secondary backup paths next. The results on five networks show that the network redundancy using dedicated 1+1+1 is in the range of 313-400%. It drops to 96-181% in 1:1:1 without loss of dual-link resiliency, but with the trade-off of using the complicated share capacity sharing among backup paths. The hybrid 1+1:1 provides intermediate redundancy ratio at 187-310% with a moderate complexity. We also compare the passive/active approaches which consider spare capacity sharing after/during the backup path routing process. The active sharing approaches always achieve lower redundancy values than the passive ones. These reduction percentages are about 12% for 1+1:1 and 25% for 1:1:1 respectively
Tensor-Aware Energy Accounting
With the rapid growth of Artificial Intelligence (AI) applications supported
by deep learning (DL), the energy efficiency of these applications has an
increasingly large impact on sustainability. We introduce Smaragdine, a new
energy accounting system for tensor-based DL programs implemented with
TensorFlow. At the heart of Smaragdine is a novel white-box methodology of
energy accounting: Smaragdine is aware of the internal structure of the DL
program, which we call tensor-aware energy accounting. With Smaragdine, the
energy consumption of a DL program can be broken down into units aligned with
its logical hierarchical decomposition structure. We apply Smaragdine for
understanding the energy behavior of BERT, one of the most widely used language
models. Layer-by-layer and tensor-by-tensor, Smaragdine is capable of
identifying the highest energy/power-consuming components of BERT. Furthermore,
we conduct two case studies on how Smaragdine supports downstream toolchain
building, one on the comparative energy impact of hyperparameter tuning of
BERT, the other on the energy behavior evolution when BERT evolves to its next
generation, ALBERT
Intensional Effect Polymorphism
Type-and-effect systems are a powerful tool for program construction and verification. We describe intensional effect polymorphism, a new foundation for effect systems that integrates static and dynamic effect checking. Our system allows the effect of polymorphic code to be intensionally inspected through a lightweight notion of dynamic typing. When coupled with parametric polymorphism, the powerful system utilizes runtime information to enable precise effect reasoning, while at the same time retains strong type safety guarantees. We build our ideas on top of an imperative core calculus with regions. The technical innovations of our design include a relational notion of effect checking, the use of bounded existential types to capture the subtle interactions between static typing and dynamic typing, and a differential alignment strategy to achieve efficiency in dynamic typing. We demonstrate the applications of intensional effect polymorphism in concurrent programming, security, graphical user interface access, and memoization
Cofilin Activation in Peripheral CD4 T Cells of HIV-1 Infected Patients: A Pilot Study
Cofilin is an actin-depolymerizing factor that regulates actin dynamics critical for T cell migration and T cell activation. In unstimulated resting CD4 T cells, cofilin exists largely as a phosphorylated inactive form. Previously, we demonstrated that during HIV-1 infection of resting CD4 T cells, the viral envelope-CXCR4 signaling activates cofilin to overcome the static cortical actin restriction. In this pilot study, we have extended this in vitro observation and examined cofilin phosphorylation in resting CD4 T cells purified from the peripheral blood of HIV-1-infected patients. Here, we report that the resting T cells from infected patients carry significantly higher levels of active cofilin, suggesting that these resting cells have been primed in vivo in cofilin activity to facilitate HIV-1 infection. HIV-1-mediated aberrant activation of cofilin may also lead to abnormalities in T cell migration and activation that could contribute to viral pathogenesis.Department of Defense (National Defense Science and Engineering Fellowship); National Institute of Allergy and Infectious Diseases (AI069981
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