505 research outputs found
A survey to investigate the association of pain, foot disability and quality of life with corns
Background
Corns are a common foot problem affecting a large proportion of the population. This study describes the characteristics of corns experienced by 201 participants taking part in a randomised controlled trial to investigate associations between demographic and corn parameters on pain, foot related disability and quality of life (QoL).
Methods
Pain from the main (index) corn was measured using a visual analogue scale (VAS); foot related disability was assessed with the Foot Disability Questionnaire (now known as the Manchester Foot Pain and Disability Index) and quality of life was recorded with the EQ-5D questionnaire. The effect of demographic and corn parameters on the pain and quality of life outcomes was assessed with analysis of variance (ANOVA) methods. The effect of the same factors on a linear combination of the foot-related disability outcome measures was assessed using multivariate ANOVA methods. Pain was also tested for its mediating properties on the causal pathway between the independent variables and quality of life.
Results
The mean pain score was 5.29 points on a 10 cm VAS, with females reporting substantively higher pain levels than males. Age affected foot-related disability, with lower levels on all domains of the MFPDI reported in older participants; each year of advancing age was associated with falls of: 0.009 points on the Concern about Appearance (CA) domain; 0.047 points on the Functional Limitation (FL) domain and 0.048 points on the Pain Intensity (PI) domain. Sex and corn type also affected disability, with higher scores reported by females and participants with plantar corns.
Conclusions
The effect of pain was shown to mediate the relationship between sex and foot-related disability. The presence of plantar corns has a more detrimental effect on QoL than dorsal/inter-digital corns
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Fluids, evaporation and precipitates at Gale Crater
The Mars Science Laboratory (MSL) mission landed in Gale Crater, Mars, on 6th August 2012, and has explored the Yellowknife Bay area. The detailed mineralogical and sedimentological studies provide a unique opportunity to characterise the secondary fluids associated with this habitable environment
Yet Another Extension of the Standard Model: Oases in the Desert?
We have searched for conceptually simple extensions of the standard model,
and describe here a candidate model which we find attractive. Our starting
point is the assumption that off-diagonal CKM mixing matrix elements are
directly related by lowest order perturbation theory to the quark mass
matrices. This appears to be most easily and naturally implemented by assuming
that all off-diagonal elements reside in the down-quark mass matrix. This
assumption is in turn naturally realized by introducing three generations of
heavy, electroweak-singlet down quarks which couple to the Higgs sector
diagonally in flavor, while mass-mixing off-diagonally with the light
down-quarks. Anomaly cancellation then naturally leads to inclusion of
electroweak vector-doublet leptons. It is then only a short step to completing
the extension to three generations of fundamental representations of E(6).
Assuming only that the third generation B couples to the Higgs sector at least
as strongly as does the top quark, the mass of the B is roughly estimated to
lie between 1.7 TeV and 10 TeV, with lower-generation quarks no heavier. The
corresponding guess for the new leptons is a factor two lower. Within the
validity of the model, flavor and CP violation are ``infrared'' in nature,
induced by semi-soft mass mixing terms, not Yukawa couplings. If the Higgs
couplings of the new quarks are flavor symmetric, then there necessarily must
be at least one ``oasis'' in the desert, induced by new radiative corrections
to the top quark and Higgs coupling constants, and roughly at 1000 TeV.Comment: LaTex, 40 page
Dark Force Detection in Low Energy e-p Collisions
We study the prospects for detecting a light boson X with mass m_X < 100 MeV
at a low energy electron-proton collider. We focus on the case where X
dominantly decays to e+ e- as motivated by recent "dark force" models. In order
to evade direct and indirect constraints, X must have small couplings to the
standard model (alpha_X 10 MeV).
By comparing the signal and background cross sections for the e- p e+ e- final
state, we conclude that dark force detection requires an integrated luminosity
of around 1 inverse attobarn, achievable with a forthcoming JLab proposal.Comment: 38 pages, 19 figures; v2, references adde
Comparison between variable flavor number schemes for charm quark electroproduction
Where appropriate, the abbreviation 'VFNS' is replaced by 'CSN' to indicate
the scheme using massive heavy quark coefficient functions proposed in this
paper. The text below Eq. (2.13) and between Eqs. (2.33) and (2.36) has been
considerably changed.Comment: 64 pages, LaTeX, 16 Postscript figure
Don't Stop Thinking About Leptoquarks: Constructing New Models
We discuss the general framework for the construction of new models
containing a single, fermion number zero scalar leptoquark of mass GeV which can both satisfy the D0/CDF search constraints as well as
low energy data, and can lead to both neutral and charged current-like final
states at HERA. The class of models of this kind necessarily contain new
vector-like fermions with masses at the TeV scale which mix with those of the
Standard Model after symmetry breaking. In this paper we classify all models of
this type and examine their phenomenological implications as well as their
potential embedding into SUSY and non-SUSY GUT scenarios. The general coupling
parameter space allowed by low energy as well as collider data for these models
is described and requires no fine-tuning of the parameters.Comment: Modified text, added table, and updated reference
Age and gender differences in disabling foot pain using different definitions of the manchester foot pain and disability index
Extent: 9p.Background: The Manchester Foot Pain and Disability Index (MFPDI) has been used to determine the prevalence of disabling foot pain in several studies, however there is some debate as to which case definition is most appropriate. The objective of this study was to explore age and gender differences in the proportion of people with disabling foot pain using three different case definitions of the MFPDI and for each individual MFPDI item. Methods: A random sample of 223 participants aged 27 to 90 years (88 males and 135 females) from the North West Adelaide Health Study, who reported having pain, aching or stiffness in either of their feet on most days in the last month, completed the MFPDI by telephone interview. The proportion of people with disabling foot pain was determined using three definitions: (i) Definition A-at least one of the 17 items documented on at least some days in the last month; (ii) Definition B-at least one of the 17 items documented on most/every day(s) in the last month, and; (iii) Definition C-at least one of the ten functional limitation items documented on most/every day(s) in the last month. Cross-tabulations and chi-squared statistics were used to explore differences in responses to the MFPDI items according to age and gender. Results: The proportion of people with disabling foot pain according to each definition was as follows: Definition A (100%), Definition B (95.1%) and Definition C (77.6%). Definition C was most sensitive to age and gender differences. Exploration of individual MFPDI items indicated that age significantly affected both the pain intensity and functional limitation items, with younger people more likely to report their foot pain being worse in the morning, and older people more likely to report functional limitations. Although gender did not influence responses to the personal appearance items, women were more likely report functional limitations than men. Conclusions: Definition C of the MFPDI is more sensitive to age and gender differences in the proportion of people with disabling foot pain, and would therefore seem to be the most appropriate case definition to use in epidemiological studies involving a broad age range of participants.Hylton B Menz, Tiffany K Gill, Anne W Taylor and Catherine L Hil
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