3,003 research outputs found

    Recorded displacements in a landslide slope due to regional and teleseismic earthquakes

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    Regional and teleseismic earthquakes can induce displacements along joints in a landslideinvolved rocky slope in Central Italy. The rarity of these effects is due to specific physical properties of the seismic signals associated with: (i) the energy content, (ii) the distribution of relative energy and peak of ground acceleration related to the ground motion components and (iii) the spectral amplitude distribution in the frequency domain; these properties allow the triggering earthquakes to be distinguished from the others. The observed effects are relevant when compared to the direction of the landslide movement and the dimensions of the involved rock mass volume. The landslide movement is less constrained in the direction parallel to the dip of the slope and the landslide dimensions are associated with characteristic periods that control the landslide deformational response in relation to the spectral content of the ground motion. The earthquake-induced displacements are significant because they have the same order of magnitude as the average annual cumulative displacement based on a decade of strain measurements within the slope

    Analisis Sistem Antrean Pelayanan Di Kantor Pertanahan Kota Semarang

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    Kantor Pertanahan Kota Semarang in charge of the land with an area of 373.70 km2 coverage, every day crowded with visitors who want to take care of the land petition. However, the high number of applicants who must be served not proportional to the number of care facilities available to the applicant should enter the waiting list queue or experiencing situation. This situation occurs in almost all counters, namely Counter 1 Land Information, Counter 2 Registration, Counter 3 Payment, and Counter 4 Product Delivery. Therefore, the required analysis is based on the model line system in accordance with the conditions of service which can then be used to address the issue queue. Based on the analysis, the model system is the best line in counter 1 land information (M/M/1): (GD/∞/∞). Counter 2 registration which is divided into 7 sub-counters have a model (M/M/2): (GD/∞/∞) to sub counters 2A, 2B, 2C, 2E/F, 2G, 2H, and the model (M/M/4): (GD/∞/∞) to sub counter 2D. Counter 3 payment (M/M/2): (GD/∞/∞). Counter 4 is the product delivery (M/M/2): (GD/∞/∞)

    gp91phox-dependent expression of platelet CD40 ligand

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    Background-CD40 ligand (CD40L) expression on platelets is mediated by agonists, but the underlying mechanism is still unclear. Methods and Results-CD40L expression was measured in platelets from healthy subjects both with and without the addition of antioxidants or a phospholipase A2 (PLA2) inhibitor and in platelets from 2 patients with an inherited deficiency of gp91phox. Immunoprecipitation analysis was also performed to determine whether normal platelets showed gp91phox expression. Unlike catalase and mannitol, superoxide dismutase inhibited agonist-induced platelet CD40L expression in healthy subjects. Immunoprecipitation analysis also showed that platelets from healthy subjects expressed gp91phox. In 2 male patients with inherited gp91phox deficiency, collagen-, thrombin-, and arachidonic acid-stimulated platelets showed an almost complete absence of superoxide anion (O2-) and CD40L expression. Incubation of platelets from healthy subjects with a PLA2 inhibitor almost completely prevented agonist-induced O2- and CD40L expression. Conclusions-These data provide the first evidence that platelet CD40L expression occurs via arachidonic acid-mediated gp91phox activation

    Engineering-geology model of the seismically-induced Cerda landslide

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    Management of lymphoma survivor patients in Italy: an evaluation by Fondazione Italiana Linfomi

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    Several outpatient models for the follow-up of cancer survivors have been developed worldwide. A multidisciplinary approach is often necessary to guarantee the best monitoring of long-term toxicities. Guidelines also indicate a close education on healthy lifestyles. In this context, we have analyzed the Italian follow-up modalities of lymphoma survivors, with the aim to have a starting line to hypothesize and plan the best model for Italian hematology centers

    Proteinuria in focal segmental glomerulosclerosis: role of circulating factors and therapeutic approach.

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    The clinical course of primary Focal Segmental Glomerulosclerosis (FSGS) is frequently complicated by nephrotic range proteinuria and progression to renal failure. The high recurrence rate of the disease in transplanted kidney suggests the hypothesis that such patients have a circulating factor that alters glomerular capillary permeability. In recent years some authors found that serum from patients with FSGS increases glomerular permeability to albumin and partially identified the permeability factor (PF) as a protein of 30-50 Kd m.w. The removal of this protein by means of Plasma Exchange (PE) or plasma Immunoadsorption by Protein A (IA) decreased proteinuria. In this report we provide preliminary data about the prevalence of PF and the therapeutic effect of its removal by IA, in 3 pts with recurrence in the transplanted kidney, and 4 with FSGS of the native kidneys. They were resistant to corticosteroids (CS) and immunosuppressive (IS) therapy. 10 IA sessions were performed in 4 weeks: if a remission was achieved IA was gradually tapered. The level of PF in the serum was measured by an in vitro assay to determine the glomerular permeability to albumin. The FSGS was histologically proven in all cases and the degree of evolution was evaluated. PF levels, serum creatinine, daily proteinuria and serum albumin were monitored. The 3 patients with recurrent FSGS had a normalization of the PF levels; 2 had a clinical remission. In FSGS of native kidneys PF was elevated in 3/4 cases; 1 had a clinical remission; 2 with extensive sclerohyalinosis and 1 without PF levels did not improve. Our results confirm that most patients with FSGS have high PF serum levels and suggest that its removal can be beneficial
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