677 research outputs found

    Web-based Social Collaborative Authoring Technology

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    This paper describes collaborative social authoring technology using web-based distributed user interface (DUI). In view of collaboration, web is one of the most common user environments on various systems of desktop and mobile devices. This paper addresses the DUI issues for the support of multiple kind of devices, such as PC, smartphone, tablet and so on. In our system, we define CAM (Collaborative Authoring Metadata). CAM is used for the exchange of authoring intention of each user during the collaborative authoring. We define elements of CAM that is useful for exchanging information among distributed users. Our system also provides the recommendation function for referring and adding the related media from the participantsā€™ social media service account during the authoring process

    Indole and 3-indolylacetonitrile inhibit spore maturation in Paenibacillus alvei

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    <p>Abstract</p> <p>Background</p> <p>Bacteria use diverse signaling molecules to ensure the survival of the species in environmental niches. A variety of both Gram-positive and Gram-negative bacteria produce large quantities of indole that functions as an intercellular signal controlling diverse aspects of bacterial physiology.</p> <p>Results</p> <p>In this study, we sought a novel role of indole in a Gram-positive bacteria <it>Paenibacillus alvei </it>that can produce extracellular indole at a concentration of up to 300 Ī¼M in the stationary phase in Luria-Bertani medium. Unlike previous studies, our data show that the production of indole in <it>P. alvei </it>is strictly controlled by catabolite repression since the addition of glucose and glycerol completely turns off the indole production. The addition of exogenous indole markedly inhibits the heat resistance of <it>P. alvei </it>without affecting cell growth. Observation of cell morphology with electron microscopy shows that indole inhibits the development of spore coats and cortex in <it>P. alvei</it>. As a result of the immature spore formation of <it>P. alvei</it>, indole also decreases <it>P. alvei </it>survival when exposed to antibiotics, low pH, and ethanol. Additionally, indole derivatives also influence the heat resistance; for example, a plant auxin, 3-indolylacetonitrile dramatically (2900-fold) decreased the heat resistance of <it>P. alvei</it>, while another auxin 3-indoleacetic acid had a less significant influence on the heat resistance of <it>P. alvei</it>.</p> <p>Conclusions</p> <p>Together, our results demonstrate that indole and plant auxin 3-indolylacetonitrile inhibit spore maturation of <it>P. alvei </it>and that 3-indolylacetonitrile presents an opportunity for the control of heat and antimicrobial resistant spores of Gram-positive bacteria.</p

    Vip-Focused Crm Strategies In An Open-Market

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    Nowadays, an open-market which provides sellers and consumers a cyber place for making a transaction over the Internet has emerged as a prevalent sales channel because of convenience and relatively low price it provides. However, there are few studies about CRM strategies based on VIP consumers for an open-market even though understanding VIP consumersā€™ behaviours in an open-market is absolutely important to increase its revenue. Therefore, we propose CRM strategies focused on VIP customers, obtained by analyzing the transaction data of VIP customers from an open-market using data mining techniques. To that end, we first defined the VIP customers in terms of recency, frequency and monetary (RFM) values. Then, we used data mining techniques to develop a model which best classifies customers into VIPs or non-VIPs. We also validate each of promotion types in the aspect of effectiveness to VIP customers and identify association rules among the types from the transactions of VIP customers. Then, based on the findings from these experiments, we propose strategies from the perspectives of CRM dimensions such as customer identification, attraction, retention and development for the open-market to thrive

    UKIRT Widefield Infrared Survey for Fe+

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    The United Kingdom Infrared Telescope (UKIRT)Widefield Infrared Survey for Fe+ (UWIFE) is a 180 deg2 imaging survey of the first Galactic quadrant (7ƂĀ° &lt; l &lt; 62ƂĀ° |b| &lt;1ƂĀ°.5) that uses a narrow-band filter centred on the [Fe II] 1.644-ƎĀ¼m emission line. The [Fe II] 1.644-ƎĀ¼m emission is a good tracer of dense, shock-excited gas, and the survey will probe violent environments around stars: star-forming regions, evolved stars, and supernova remnants, among others. The UWIFE survey is designed to complement the existing UKIRTW idefield Infrared Survey for H2 (UWISH2). The survey will also complement existing broad-band surveys. The observed images have a nominal 5Ə? detection limit of 18.7 mag for point sources, with a median seeing of 0.83 arcsec. For extended sources, we estimate a surface brightness limit of 8.1 ƃ? 10-20 W m-2 arcsec-2. In this paper, we present an overview and some preliminary results of this survey. ƂĀ© 2014 The Authors Published by Oxford University Press on behalf of the Royal Astronomical Society

    Recent Changes in the Clinicopathologic Features of Korean Men with Prostate Cancer: A Comparison with Western Populations

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    Purpose : The aim of this study was to evaluate the recent changes in the clinicopathologic features of prostate cancer in Korea and to compare these features with those of Western populations. Materials and methods : We retrospectively reviewed the data of 1582 men undergoing radical prostatectomy for clinically localized prostate cancer between 1995 and 2007 at 10 institutions in Korea for comparison with Western studies. The patients were divided into two groups in order to evaluate the recent clinicopathological changes in prostate cancer: Group 1 had surgery between 1995 and 2003 (n=280) and Group 2 had surgery between 2004 and 2007 (n=1302). The mean follow-up period was 24 months. Results : Group 1 had a higher prostate-specific antigen level than Group 2 (10.0 ng/mL vs. 7.5 ng/mL, respectively; p<0.001) and a lower proportion of biopsy Gleason scores ā‰¤6 (35.0% vs. 48.1%, respectively; p<0.001). The proportion of patients with clinical T1 stage was higher in Group 2 than in Group 1. Group 1 had a lower proportion of organ-confined disease (59.6% vs. 68.6%; p<0.001) and a lower proportion of Gleason scores ā‰¤6 (21.3% vs. 33.0%; p<0.001), compared to Group 2. However, the relatively higher proportion of pathologic Gleason scores ā‰¤6 in Group 2 was still lower than those of Western men, even though the proportion of organ-confined disease reached to that of Western series. Conclusion : Korean men with prostate cancer currently present better clinicopathologic parameters. However, in comparison, Korean men still show relatively worse pathologic Gleason scores than Western men.ope
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