Risk factors of prelabor rupture of membranes at University of Maiduguri Teaching Hospital, Maiduguri: A cross‑sectional study

Background: Prelabor rupture of membranes (PROM) is a common obstetrics problem associated with maternal and perinatal morbidity and mortality.Patients and Methods: This was a hospital-based cross-sectional study to determine the risk factors for PROM among women presenting to the Department of Obstetrics and Gynecology of the University of Maiduguri Teaching Hospital, Maiduguri. It was conducted between 1st May 2016 and 28th February 2017. Sociodemographic and obstetrics variables were obtained from the patients, and risk factors such as previous preterm delivery, previous PROM, miscarriages, fever, abnormal vaginal discharge, urinary tract infection, abdominal distension, trauma, and coitus were sought. For each patient, an endocervical swab, high vaginal swab, and urine samples were taken for microbacteriologic studies. The next patient without PROM is used as control. Data were analyzed using SPSS 20. A total of 258 (129 with PROM and another 129 without PROM) were analyzed.Results: The mean age, gestational age, and parity were 27 ± 6 years, 33 ± 0.3 weeks, and 1 ± 0.92, respectively. A majority of the women (55%) had parity between 1 and 4. Term PROM recorded the highest frequency [49 (37.9%)]. Previous history of PROM [odds ratio (OR) 5.18, 95% confidence interval (CI): 2.31–11.62], history of Preterm Delivery (OR 3.26, 95% CI: 1.16– 9.19), low socioeconomic status (OR 1.95 95%, CI: 1.15–3.31), and genitourinary infection are highly predictive of PROM.Conclusion: The modifiable or treatable risk factors should be addressed during the antenatal care to reduce the risk of PROM. High-risk patients should be counseled and monitored closely to optimize pregnancy outcomes.Keywords: Maiduguri; morbidity; mortality; prelabor rupture of membranes; risk factor

Genetic analysis of male sterility genes in different A and B sorghum lines

Hybrid seed production requires use of cytoplasmic male sterility (CMS). Without this system, hybrid seed production would not be economically feasible. There is, therefore, need for developing A and B sorghum lines, as an essential step for development of hybrid sorghum industry. A genetic study of male sterility in different A and B sorghum ( Sorghum bicolor (L.) Moench) lines was conducted at the research farm Institute for Agriculture Research in Samaru and Kadawa. Chi-square test revealed goodness-of-fit to single gene of observed proportion of sterile and fertile plants to the expected ratio in all the backcross generations, thereby upholding the assumption of single gene inheritance for the traits studied. Stability of male sterile genes across generations of backcrosses indicated that sterility was inherited 68 to 95% among the different genotypes. Based on high number of sterile plants, crosses 159 x 160 and 421 x 422 are the best in terms of breeding potential for male sterility.La production des semences hybrides n\ue9cessite l\u2019utilisation de la st\ue9rilit\ue9 m\ue2le cytoplasmique (CMS). Sans ce syst\ue8me, la production des semences hybrides ne serait pas \ue9conomiquement faisable. Il y a donc, un besoin pour d\ue9velopper des lign\ue9es A et B du sorgho, comme une \ue9tape essentielle dans le d\ue9veloppement d\u2019industrie de sorgho hybride. Une \ue9tude g\ue9n\ue9tique de la st\ue9rilit\ue9 m\ue2le dans diff\ue9rentes lign\ue9es A et B du sorgho ( Sorghum bicolor (L.) Moench) a \ue9t\ue9 conduite \ue0 la ferme d\u2019exp\ue9rimentation de l\u2019Institut des Recherches Agricoles de Samaru et Kadawa. Le test de Chi-carr\ue9 a r\ue9v\ue9l\ue9 la qualit\ue9 d\u2019association d\u2019un seul g\ue8ne de la proportion observ\ue9e de plants st\ue9riles et fertiles au ratio observ\ue9 dans les g\ue9n\ue9rations de r\ue9trocroisement, ainsi soutenant l\u2019hypoth\ue8se de l\u2019h\ue9ritage d\u2019un g\ue8ne pour les traits \ue9tudi\ue9s. La stabilit\ue9 de g\ue8nes de la st\ue9rilit\ue9 m\ue2le \ue0 travers les g\ue9n\ue9rations du r\ue9trocroisement a indiqu\ue9 que la st\ue9rilit\ue9 \ue9tait h\ue9rit\ue9e entre 68 \ue0 95% entre les diff\ue9rents g\ue9notypes. Sur la base du nombre \ue9lev\ue9 de plantes st\ue9riles, les croisements 159 x 160 et 421 x 422 sont les meilleurs en termes du potentiel d\u2019am\ue9lioration g\ue9n\ue9tique pour la st\ue9rilit\ue9 m\ue2le