Direct inactivation of different concentrations of essential oil on HSV-1 at various times as determined by plaque reduction assay

<p><b>Copyright information:</b></p><p>Taken from "Antiherpevirus activity of essential oil and inhibition of lateral diffusion in Vero cells"</p><p>http://www.ann-clinmicrob.com/content/6/1/10</p><p>Annals of Clinical Microbiology and Antimicrobials 2007;6():10-10.</p><p>Published online 26 Sep 2007</p><p>PMCID:PMC2099429.</p><p></p> HSV-1 was mixed with essential oil and incubated for 15 min. (black circle), 1 h (black square) or 2 h (white circle) at 37°C. ICof 2.4 μg/ml as determined after 1 h pre-incubation at 37°C, shifted to 1.14 μg/ml and 6.9 μg/ml when HSV-1 was pre-incubated for 2 h or 15 min, respectively. Results are presented as mean percentage of control of three separate experiments

Neutralizing activity of essential oil against HSV-1 as determined by plaque reduction assay after 1 h pre-incubation at 37°C (black square) or 4°C (black circle)

<p><b>Copyright information:</b></p><p>Taken from "Antiherpevirus activity of essential oil and inhibition of lateral diffusion in Vero cells"</p><p>http://www.ann-clinmicrob.com/content/6/1/10</p><p>Annals of Clinical Microbiology and Antimicrobials 2007;6():10-10.</p><p>Published online 26 Sep 2007</p><p>PMCID:PMC2099429.</p><p></p> ICof 2.4 μg/ml as determined after 1 h pre-incubation at 37°C, increased to 19.4 μg/ml when HSV-1 was pre-incubated for the same time at 4°C. Results are presented as mean percentage of control of four separate experiments

Cytotoxic Phloroglucinols from the Leaves of <i>Myrtus communis</i>

Bioactivity-guided fractionation of a dichloromethane extract of the leaves of <i>Myrtus communis</i> led to the isolation of phloroglucinol derivatives. The structures of the new myrtucommulones J, K, and L (<b>1</b>–<b>3</b>) and the previously known myrtucommulone A (<b>4</b>) were elucidated on the basis of extensive 1D and 2D NMR experiments as well as high-resolution mass spectrometry. Myrtucommulone J was obtained as a tautomeric pair (<b>1</b>/<b>1a</b>). The compounds were tested in vitro for their cytotoxic and antibacterial activities