933 research outputs found
Online tracking: Questioning the power of informed consent
Online tracking technologies have raised considerable concerns regarding privacy and the protection of personal data of users. In order to help users to regain control over their personal data, Europe has amended its ePrivacy directive towards an opt-in regime. There are however many open questions concerning its implementation, especially regarding the issue of informed consent. This paper explores how the new legal situation impacts on behavioral advertising practices via the storing and reading of cookies in the Netherlands. The results show that the majority of the surveyed parties involved in behavioural advertising do not inform users about the storing of cookies or the purposes of data processing of the subsequently obtained data, neither do they have obtained users' consent for the storage of cookies. We also found that the majority of users lack the skills and knowledge how to handle cookies. These findings critically question the wisdom of the informed consent regime which lies currently at the heart of Europe's ePrivacy directive. --Online behavioural advertising,profiling,cookies,informed consent,Do Not Track,ePrivacy Directive
The influence of the polyene filipin on the extrinsic pathway of blood coagulation
The inhibition by filipin in the extrinsic blood clotting system takes place at two sites: (1) at the interaction of factor VII, tissue thromboplastin and Ca++, and (2) at the prothrombinase level. Both formation and enzymatic activity of the prothrombinase are inhibited.The cholesterol content of the lipid that is used to form the prothrombinase complex determines the degree of inhibition by filipin. The inhibition increases the higher the sterol content. The adsorption of factors Xa and V onto lipid surface is enhanced by filipin. This increased adsorption does not lead to an increase in prothrombinase production
An Inner Gaseous Disk around the Herbig Be Star MWC 147
We present high-spectral-resolution, optical spectra of the Herbig Be star
MWC 147, in which we spectrally resolve several emission lines, including the
[O I] lines at 6300 and 6363\deg. Their highly symmetric, double-peaked line
profiles indicate that the emission originates in a rotating circumstellar
disk. We deconvolve the Doppler-broadened [O I] emission lines to obtain a
measure of emission as a function of distance from the central star. The
resulting radial surface brightness profiles are in agreement with a disk
structure consisting of a flat, inner, gaseous disk and a flared, outer, dust
disk. The transition between these components at 2 to 3 AU corresponds to the
estimated dust sublimation radius. The width of the double-peaked Mg II line at
4481\deg suggests that the inner disk extends to at least 0.10 AU, close to the
corotation radius.Comment: accepted for ApJ Letters (Oct. 2010
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