The Glass Transition in Driven Granular Fluids: A Mode-Coupling Approach

We consider the stationary state of a fluid comprised of inelastic hard spheres or disks under the influence of a random, momentum-conserving external force. Starting from the microscopic description of the dynamics, we derive a nonlinear equation of motion for the coherent scattering function in two and three space dimensions. A glass transition is observed for all coefficients of restitution, epsilon, at a critical packing fraction, phi_c(epsilon), below random close packing. The divergence of timescales at the glass-transition implies a dependence on compression rate upon further increase of the density - similar to the cooling rate dependence of a thermal glass. The critical dynamics for coherent motion as well as tagged particle dynamics is analyzed and shown to be non-universal with exponents depending on space dimension and degree of dissipation.Comment: 16 pages, 9 figure

Two mechanisms that account for major histocompatibility complex restriction of T cells

In recent studies, two distinct mechanisms have been proposed to account for major histocompatibility complex (MHC) restriction of T-cell activity: (a) evolution-driven interactions between T-cell receptor (TCR) variable regions and MHC, and (b) a requirement for CD4 or CD8 binding to MHC to initiate signalling through the TCR complex. Both mechanisms are likely to be essential, but for different reasons

Benchmarking high fidelity single-shot readout of semiconductor qubits

Determination of qubit initialisation and measurement fidelity is important for the overall performance of a quantum computer. However, the method by which it is calculated in semiconductor qubits varies between experiments. In this paper we present a full theoretical analysis of electronic single-shot readout and describe critical parameters to achieve high fidelity readout. In particular, we derive a model for energy selective state readout based on a charge detector response and examine how to optimise the fidelity by choosing correct experimental parameters. Although we focus on single electron spin readout, the theory presented can be applied to other electronic readout techniques in semiconductors that use a reservoir.Comment: 19 pages, 8 figure

T Cells Use Rafts for Survival

T cell homeostasis must be tightly controlled. In this issue of Immunity, Cho et al. (2010) describe results that begin to define the roles of the T cell receptor, self-peptide-MHC ligands, cytokines, and membrane rafts in this dynamic process

Partitioning of energy in highly polydisperse granular gases

A highly polydisperse granular gas is modeled by a continuous distribution of particle sizes, a, giving rise to a corresponding continuous temperature profile, T(a), which we compute approximately, generalizing previous results for binary or multicomponent mixtures. If the system is driven, it evolves towards a stationary temperature profile, which is discussed for several driving mechanisms in dependence on the variance of the size distribution. For a uniform distribution of sizes, the stationary temperature profile is nonuniform with either hot small particles (constant force driving) or hot large particles (constant velocity or constant energy driving). Polydispersity always gives rise to non-Gaussian velocity distributions. Depending on the driving mechanism the tails can be either overpopulated or underpopulated as compared to the molecular gas. The deviations are mainly due to small particles. In the case of free cooling the decay rate depends continuously on particle size, while all partial temperatures decay according to Haff's law. The analytical results are supported by event driven simulations for a large, but discrete number of species.Comment: 10 pages; 5 figure

Percolation with long-range correlated disorder

Long-range power-law correlated percolation is investigated using Monte Carlo simulations. We obtain several static and dynamic critical exponents as function of the Hurst exponent $H$ which characterizes the degree of spatial correlation among the occupation of sites. In particular, we study the fractal dimension of the largest cluster and the scaling behavior of the second moment of the cluster size distribution, as well as the complete and accessible perimeters of the largest cluster. Concerning the inner structure and transport properties of the largest cluster, we analyze its shortest path, backbone, red sites, and conductivity. Finally, bridge site growth is also considered. We propose expressions for the functional dependence of the critical exponents on $H$

A reactive soil moisture sensor network: Design and field evaluation

Wireless sensor network technology has the potential to reveal finegrained, dynamic changes in monitored variables of an outdoor landscape. But there are significant problems to be overcome in order to realize this vision in working systems. This paper describes the design and implementation of a reactive, event driven network for environmental monitoring of soil moisture and evaluates its effectiveness. A novel feature of our solution is its reactivity to the environment: when rain falls and soil moisture is changing rapidly, measurements are collected frequently, whereas during dry periods, between rainfall, measurements are collected less often. Field trials demonstrating the reactivity, robustness, and longevity of the network are presented and evaluated, and future improvements proposed

Drosophila bloom helicase maintains genome integrity by inhibiting recombination between divergent DNA sequences

DNA double strand breaks (DSB) can be repaired either via a sequence independent joining of DNA ends or via homologous recombination. We established a detection system in D. melanogaster to investigate the impact of sequence constraints on the usage of the homology based DSB repair via single strand annealing (SSA), which leads to recombination between direct repeats with concomitant loss of one repeat copy. First of all, we find the SSA frequency to be inversely proportional to the spacer length between the repeats, for spacers up to 2.4 kb in length. We further show that SSA between divergent repeats (homeologous SSA) is suppressed in cell cultures and in vivo in a sensitive manner, recognizing sequence divergences smaller than 0.5%. Finally, we demonstrate that the suppression of homeologous SSA depends on the Bloom helicase (Blm), encoded by the Drosophila gene mus309. Suppression of homeologous recombination is a novel function of Blm in ensuring genomic integrity, not described to date in mammalian systems. Unexpectedly, distinct from its function in S. cerevisiae, the mismatch repair (MMR) factor Msh2 encoded by spel1 does not suppress homeologous SSA in Drosophil