3,819 research outputs found
Electronic properties of very thin native SiO2/a-Si:H interfaces and their comparison with those prepared by both dielectric barrier discharge oxidation at atmospheric pressure and by chemical oxidation
The contribution deals with electronic properties of thin oxide/amorphous hydrogenated silicon (a-Si:H) measured by capacitance-voltage (C-V) and charge version of deep level transient spectroscopy (Q-DLTS). The interest was focused on the studies of the interface properties of very thin dielectrics formed by dielectric barrier discharge (DBD) or natively on the a-Si:H layer. These properties were compared with those of oxide layers prepared by chemical oxidation in HNO3. The DBD was used for the preparation of a very thin SiO2 layer on a-Si:H for the first time to our knowledge. Preliminary electrical measurements confirmed that a very low interface states density was detected in the case of the native oxide/a-Si:H and DBD oxide/a-Si:H
In Vitro Flouride Resistance in a Cariogenic Streptococcus
Author Institution: Department of Botany and Microbiology, University of ArkansasStable fluoride-resistant mutants of Streptococcus mutans GS-5 were isolated with a stepwise selection procedure. First-step mutants were isolated at a frequency of 6.4 X 10~10 and demonstrated six maximal levels of resistance ranging from 400-1000 ug/ml sodium fluoride. Second-step mutants with higher levels of resistance were isolated at a frequency of 1.4 X 10~8. Second-step mutants demonstrated two maximal levels of resistance, 1600 and 3000 ug/ml sodium fluoride. Other than fluoride resistance, the characteristics of both first- and second-step mutants were similar to those of the parental strain. Growth rates did differ, however. First-step mutants exhibited slightly longer mass doubling times than the parental strain (average of 50 vs 45 min, respectively). Second-step mutants exhibited substantially longer mass doubling times (average of 71.5 min). The results suggest that fluoride resistance may be regulated by more than one gene, and that high levels of resistance may be due to a cumulative effect of at least two genes
Neurocognitive factors in sensory restoration of early deafness: a connectome model
Progress in biomedical technology (cochlear, vestibular, and retinal implants) has led to remarkable success in neurosensory restoration, particularly in the auditory system. However, outcomes vary considerably, even after accounting for comorbidity-for example, after cochlear implantation, some deaf children develop spoken language skills approaching those of their hearing peers, whereas other children fail to do so. Here, we review evidence that auditory deprivation has widespread effects on brain development, affecting the capacity to process information beyond the auditory system. After sensory loss and deafness, the brain's effective connectivity is altered within the auditory system, between sensory systems, and between the auditory system and centres serving higher order neurocognitive functions. As a result, congenital sensory loss could be thought of as a connectome disease, with interindividual variability in the brain's adaptation to sensory loss underpinning much of the observed variation in outcome of cochlear implantation. Different executive functions, sequential processing, and concept formation are at particular risk in deaf children. A battery of clinical tests can allow early identification of neurocognitive risk factors. Intervention strategies that address these impairments with a personalised approach, taking interindividual variations into account, will further improve outcomes
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A self-consistent model for the evolution of the gas produced in the debris disc of β Pictoris
This paper presents a self-consistent model for the evolution of gas produced in the debris disc of β Pictoris. Our model proposes that atomic carbon and oxygen are created from the photodissociation of CO, which is itself released from volatile-rich bodies in the debris disc due to grain–grain collisions or photodesorption. While the CO lasts less than one orbit, the atomic gas evolves by viscous spreading resulting in an accretion disc inside the parent belt and a decretion disc outside. The temperature, ionization fraction and population levels of carbon and oxygen are followed with the photodissociation region model CLOUDY, which is coupled to a dynamical viscous α model. We present new gas observations of β Pic, of C I observed with Atacama Pathfinder EXperiment and O I observed with , and show that these along with published CII and CO observations can all be explained with this new model. Our model requires a viscosity α > 0.1, similar to that found in sufficiently ionized discs of other astronomical objects; we propose that the magnetorotational instability is at play in this highly ionized and dilute medium. This new model can be tested from its predictions for high-resolution ALMA observations of C I. We also constrain the water content of the planetesimals in β Pic. The scenario proposed here might be at play in all debris discs and this model could be used more generally on all discs with C, O or CO detections.QK, MW and LM acknowledge support from the European Union through ERC grant number 279973. AJ acknowledges the support of the DISCSIM project, grant agreement 341137, funded by the European Research Council under ERC-2013-ADG.This is the final version of the article. It first appeared from Oxford University Press via http://dx.doi.org/10.1093/mnras/stw136
Compatibility and toxicity of polymer-coated magnetic nanoparticles on mammalian cell systems
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2005.Includes bibliographical references (p. 42-44).(cont.) produced normal growth curves in the presence of particles. However, the particles do still exhibit some toxicity towards the cells, as the maximum cell density of cells cultured with particles does not reach that of control cultures. Both particles were found to increase the oxygen transfer in an aqueous solution. A 1.5% solution of particle A enhanced the oxygen transfer 41.8% over the control, water, while 1.4% particle B enhanced 15.9% over the control. While particle A has a better effect on oxygen transfer, this particle is not suitable to be used with mammalian cell cultures as it is highly toxic.This thesis focuses on the compatibility of polymer-coated magnetic nanoparticles with mammalian systems. The magnetic particles are designed to increase oxygen transfer in mammalian cell bioreactors. Magnetic nanoparticle A consists of a magnetite core attached to a layer of oleic acid, in which oxygen is four times as soluble as it is in water. The entire particle is coated with an attached layer of a surfactant, hitenol, to stabilize the particle against agglomeration. The entire particle has a diameter of approximately 20 nm. However, particle A was found to be extremely toxic to both [gamma]-CHO and hybridoma cells, causing complete cell death within four hours. This is most likely due to the surface surfactant, hitenol. A more biocompatible nanoparticle, particle B, was created. This particle is synthesized with a brush copolymer consisting of octadecylamine (ODA) and poly(ethylene oxide) (PEO) attached to a poly(acrylic acid) backbone. Once attached to the magnetite core, the ODA forms the inner layer that solubilizes oxygen, while PEO forms the stabilizing coating. Particle B forms nanoclusters about 100 nm in diameter. Thoroughly cleaning the nanoparticles is very important, as mammalian cells are very sensitive to foreign chemicals. Particles cleaned with dialysis did not remove all impurities, as all [gamma]-CHO cells in the presences of these particles were killed within 24 hours. High gradient magnetic separation (HGMS) was used to clean particles, and was found to be a much more effective method. However, sufficient amounts of washing fluid, about sixty column volumes, were needed to ensure proper cleaning. Once properly cleaned, the particles were found to be much less toxic towards the cells. Both [gamma]-CHO and hybridoma cellsby Kelly M. Kral.S.M
Search for weakly interacting sub-eV particles with the OSQAR laser-based experiment: results and perspectives
Recent theoretical and experimental studies highlight the possibility of new
fundamental particle physics beyond the Standard Model that can be probed by
sub-eV energy experiments. The OSQAR photon regeneration experiment looks for
"Light Shining through a Wall" (LSW) from the quantum oscillation of optical
photons into "Weakly Interacting Sub-eV Particles" (WISPs), like axion or
axion-like particles (ALPs), in a 9 T transverse magnetic field over the
unprecedented length of m. No excess of events has been
detected over the background. The di-photon couplings of possible new light
scalar and pseudo-scalar particles can be constrained in the massless limit to
be less than GeV. These results are very close to the
most stringent laboratory constraints obtained for the coupling of ALPs to two
photons. Plans for further improving the sensitivity of the OSQAR experiment
are presented.Comment: 7 pages, 7 figure
Accountancy and academic/professional inter-dependency (or mutual exclusivity?)
This paper is a report on an Accounting Education Symposium held during the 2009 Annual Congress of the EAA in Tampere, Finland. This was the fourth occasion on which there has been an Accounting Education Symposium (or similar) within an EAA Annual Congress. Previous events were as follows: 2005 (Gotenburg, Sweden) EAA Accounting Educators\u27 Forum 2006 (Dublin, Ireland) \u27Universities and Professional Bodies: Complementary or Colliding Roles in Educating and Training Future Accounting Practitioners?\u27 (sponsored by the Irish Accountancy Educational Trust) 2008 (Rotterdam, the Netherlands) \u27Accounting Education: The Common Content Project\u27 (sponsored by Royal NIVRA). <br /
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