164 research outputs found
Coping with pain in the hip or knee in relation to physical disability in community-living elderly people
__Objective__ To investigate the use of pain coping strategies by community-living older people with pain in the hip or knee and the mediating role of coping with pain in the relationship between the chronicity of pain and physical disability.
__Methods__ A group of 157 people with pain 'in the last month' was identified. Coping with pain was assessed with the Pain Coping Inventory, physical disability with the Sickness Impact Profile, and household and sport activities with a validated structured interview method.
__Results__ People with chronic pain used relatively more 'resting,' and 'reducing demands' as pain coping strategies. Pain chronicity made a significant contribution to physical disability; however, when corrected for other variables in a regression model, no significant partial correlation was found.
__Conclusion__ We conclude that pain coping has a mediating role in the relationship between pain chronicity and physical disability. Less use of 'resting' and a physically active lifestyle are independently associated with less physical disability
Advancements in natural products chemistry : chemical constituents of Aplysilla pallida, Aplysilla rosea, Aplysilla var. sulphurea, Orthoscutilla maculata, and approaches to the synthesis of aplysulphurin
OBJECTIVES: Both stressors and stress vulnerability factors together with immune and hypothalamus-pituitary-adrenal (HPA) axis activity components have been considered to contribute to disease fluctuations of chronic inflammatory diseases, such as rheumatoid arthritis (RA). The aim of the present study was to investigate whether daily stressors and worrying as stress vulnerability factor as well as immune and HPA axis activity markers predict short-term disease activity and symptom fluctuations in patients with RA. METHODS: In a prospective design, daily stressors, worrying, HPA axis (cortisol) and immune system (interleukin (IL)-1beta, IL-6, IL-8, interferon (IFN)-gamma, tumour necrosis factor alpha) markers, clinical and self-reported disease activity (disease activity score in 28 joints, RA disease activity index), and physical symptoms of pain and fatigue were monitored monthly during 6 months in 80 RA patients. RESULTS: Multilevel modelling indicated that daily stressors predicted increased fatigue in the next month and that worrying predicted increased self-reported disease activity, swollen joint count and pain in the next month. In addition, specific cytokines of IL-1beta and IFN-gamma predicted increased fatigue 1 month later. Overall, relationships remained relatively unchanged after controlling for medication use, disease duration and demographic variables. No evidence was found for immune and HPA axis activity markers as mediators of the stress-disease relationship. CONCLUSIONS: Daily stressors and the stress-vulnerability factor worrying predict indicators of the short-term course of RA disease activity and fatigue and pain, while specific cytokines predict short-term fluctuations of fatigue. These stress-related variables and immune markers seem to affect different aspects of disease activity or symptom fluctuations independently in RA
Medische psychologie op maat
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30217_medipsopm.pdf (publisher's version ) (Open Access)22 p
Coping with rheumatoid arthritis: social and psychological factors
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Meeteigenschappen van vragenlijsten voor fysiek functioneren bij RA-patienten.
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Pijncoping-strategieën bij chronische pijnpatiënten: De ontwikkeling van de Pijn-Coping-Inventarisatielijst (PCI)
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24661.PDF (publisher's version ) (Open Access
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