Wearable multi-color RAPD screening device

In this work, we developed a wearable, head-mounted device that automatically calculates the precise Relative Afferent Pupillary Defect (RAPD) value of a patient. The device consists of two RGB LEDs, two infrared cameras, and one microcontroller. In the RAPD test, the parameters like LED on-off durations, brightness level, and color of the light can be controlled by the user. Upon data acquisition, a computational unit processes the data, calculates the RAPD score and visualizes the test results with a user-friendly interface.Multiprocessing methods used on GUI to optimize the processing pipeline. We have shown that our head-worn instrument is easy to use, fast, and suitable for early-diagnostics and screening purposes for various neurological conditions such as RAPD, glaucoma, asymmetric glaucoma, and anisocoria

A Novel Benzimidazole-Based Chemosensor for Fluorometric Determination of Zinc Ions

A simple and novel Schiff base chemosensor (BMHM) based on benzimidazole was synthesized. In ethanol-water (1:1, v/v) medium on varying concentrations of Zn2+ chemosensor exhibited a strong and quick turn on fluorescence response. The Zn2+ recognition was based on the Chelation-enhanced fluorescence effect. The binding constant and limit of detection for BMHM-Zn2+ complexation were estimated to be 7.99 x 104 M-1 and 0.148 mu M, respectively. The extreme fluorescent enhancement caused by Zn2+ binding in chemosensor BMHM occurred at a pH range of 6-7. The practical use of chemosensor BMHM was tested by determination of Zn2+ in real water samples and comparing the results with the data obtained using high resolution inductively coupled plasma mass spectrometry.Duzce University Scientific Research Projects UnitDuzce University [2017.05.03.620, 2019.05.03.947]This study was supported by Duzce University Scientific Research Projects Unit (Project numbers: 2017.05.03.620 and 2019.05.03.947).WOS:0006957884000032-s2.0-85114898871PubMed: 3451993

Alterations in lipid peroxidation and antioxidant status in different types of intracranial tumors within their relative peritumoral tissues

Objectives: Elevated levels of lipid peroxidation and changes in the concentration of enzymatic and nonenzymatic antioxidant systems have been reported in various cancers, but there are very few reports available of lipid peroxidation due to oxidative stress in patients with intracranial neoplasms. The purpose of this study was to assess alterations in lipid peroxidation and antioxidant status in different types of tumors and to compare the results with their relative peritumoral tissues and compare the oxidative status in different grades of tumors

The diagnostic efficiency of multislice CT virtual bronchoscopy in detecting endobronchial tumors

In this study, the diagnostic efficiency of virtual bronchoscopy, which is a new and helpful method to conventional fiberoptic bronchoscopy, has been investigated for endobronchial lung tumors and its clinical applications are discussed. 36 patients with clinically suspected lung cancer (28 males, 8 females, mean age 61; range from 39 to 74) underwent multislice computed tomography (MSCT) virtual bronchoscopy and then conventional bronchoscopy on the same day. For all patients, investigators were uninformed about results of conventional bronchoscopy. Sensitivity, specificity, positive and negative predictive values of virtual bronchoscopy were calculated using conventional bronchoscopy results as standard reference values. In 12 patients, convetional bronchoscopy did not show pathologic findings. In 24 cases pathologic findings were detected; mucosal infiltration was observed in three cases, vegetating lesions were detected in 21 cases. Review of these 21 cases demonstrated preocclusive stenosis in five and various degrees of luminal stenosis in 16 cases. All 21 tumoral lesions observed with conventional bronchoscopy were also detected with virtual bronchoscopy. Retrospective evaluation of six lesions visualized with virtual bronchoscopy but not detected with conventional bronchoscopy showed that they consisted of highly viscous mucous secretion. No abnormalities were detected on both conventional and virtual bronchoscopy in six patients. Three mucosal infiltrations observed on conventional bronchoscopy were not visualised on virtual bronchoscopy. The sensitivity of MSCT virtual bronchoscopy was 88% and specificity was 50% which is concordant with the literature. Positive predictive value, negative predictive value and accuracy was found 78%, 66% and 75%, respectively

Green ICT (Information and Communication Technologies): A Review of Academic and Practitioner Perspectives

Green ICT (Information and Communication Technologies): A Review of Academic and Practitioner Perspective

Dealing with the gray zones in the management of gastric cancer: The consensus statement of the Istanbul Group

The geographical location and differences in tumor biology significantly change the management of gastric cancer. The prevalence of gastric cancer ranks fifth and sixth among men and women, respectively, in Turkey. The international guidelines from the Eastern and Western countries fail to manage a considerable amount of inconclusive issues in the management of gastric cancer. The uncertainties lead to significant heterogeneities in clinical practice, lack of homogeneous data collection, and subsequently, diverse outcomes