375 research outputs found

    ITSM and Education

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    The purpose of this workshop is to demonstrate an extended ITSM taxonomy to the professor, and also demonstrate courses now available in Foundations of IT Services I and II, and possibly, Business Service Management, and Introduction to Cloud Computing

    IT Services Management in the Curriculum: Challenges, Realizations, and Lessons Learned

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    This panel report discussed three different ways that IT Services Management (ITSM) can be infused into the curriculum of university programs. One aspect of the panel focused on noncourse-specific means of infusing ITSM in a MSIS program, while another looked at a basic course in ITSM in the MSIS program. A final aspect described entire degree programs in ITSM and curricular support for them. Though this panel focused primarily on graduate programs, the lessons in some cases are applicable to undergraduate programs as well

    3-[(E)-1-(Benzyl­oxyimino)eth­yl]-2-oxo-2H-chromen-7-yl acetate

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    The title compound, C20H17NO5, was prepared by the reaction of 3-acetyl-2-oxo-2H-chromen-7-yl acetate with benzyl­oxy­amine. The mol­ecule adopts an E configuration with respect to the C=N double bond. The dihedral angles between the coumarin ring system, the phenyl ring and the C=N—O—C plane of the oxime unit are 35.83 (6), 35.8 (2) and 69.99 (15)°, respectively. In the crystal, a two-dimensional supra­molecular network is assembled through weak inter­molecular C—H⋯O hydrogen-bonding inter­actions

    USE OF NOVEL PSYCHOACTIVE SUBSTANCES (NPS) OF NATURAL ORIGIN: AN INTERNATIONAL SURVEY

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    Aim NPS recreational use are mostly derived and modified from constituents of natural origin. Here we investigated the motivation of natural NPS use, perception of potential associated health risks and demographic factors associated with natural NPS use. Methodology The Bristol Online Survey was in English and advertised on the drug forum Bluelight and social media Facebook pages and via University email between 1 July and 17 November 2018 (812 responses; 458 NPS users). This pharmacoepidemiologic study was evaluated using SPSS software (IBM SPSS Statistics version 24;MacOS Sierra 10.12.3). Results The main motivation (67%) for natural NPS use was curiosity to ‘’experience something new and different’’ with a low perception of health risk (85%). The preferred natural NPS was magic mushrooms (psilocybin, 95%) often in combination with cannabis (63%). Gender, living area, educational background, smoking frequency and employment significantly affected (P<0.001) natural NPS use. Male respondents, residents of suburban and rural areas, smokers and respondents with low educational level represented the majority of natural NPS users as well as the employed, the unable to work and retired groups. Similarly, sexual orientation significantly affected (p<0.05) natural NPS use. Conclusion Users’ low perception of natural NPS safety profile and the fact that natural NPS use correlates with a lower level of education, indicates a need for enhanced statutory targeted prevention interventions in schools. Many users (67%) reported natural NPS make them happier and more optimistic about life emphasizing the need to study the potential application of these substances in appropriate clinical settings for therapeutic purposes in mental health.Peer reviewe

    Selective inhibition of carotenoid cleavage dioxygenases : phenotypic effects on shoot branching

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    Members of the carotenoid cleavage dioxygenase family catalyse the oxidative cleavage of carotenoids at various chain positions, leading to the formation of a wide range of apocarotenoid signalling molecules. To explore the functions of this diverse enzyme family, we have used a chemical genetic approach to design selective inhibitors for different classes of carotenoid cleavage dioxygenase. A set of 18 arylalkyl-hydroxamic acids was synthesised in which the distance between an iron-chelating hydroxamic acid and an aromatic ring was varied; these compounds were screened as inhibitors of four different enzyme classes, either in vitro or in vivo. Potent inhibitors were found that selectively inhibited enzymes that cleave carotenoids at the 9,10 position; 50% inhibition was achieved at sub-micromolar concentrations. Application of certain inhibitors at 100 microM to Arabidopsis node explants or whole plants led to increased shoot branching, consistent with inhibition of 9,10-cleavage

    Increasing the Participation of Women in the Engineering and Technical Services Industries

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    © ASEE 2008Services have surpassed agriculture and manufacturing as the leading contributor to gross domestic product in the world today. As the global economy has become more integrated, and the demand for a workforce required to run service-focused organizations in an efficient manner grows, the level and variety of skills needed in this new service economy have also changed and grown. In particular, the growth rate of technology-driven service industries is significantly outpacing the growth in other serviceoriented sectors. It has been argued that women in general possess many characteristics that make them optimal candidates to fulfill this workforce gap. However, the percentage of women enrolled in engineering, technology and related programs have been dropping. This paper attempts to create an awareness of the skills and job roles required for future labor workforce demands in the engineering and technology services industry and argues that these current and future roles makes them more appealing to women

    Microwave-Assisted Synthesis and Evaluation of Antimicrobial Activity of 3-{3-(s-Aryl and s-Heteroaromatic)acryloyl}-2Hchromen-2-one Derivatives

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    The exploration of potential utilization of microwaves as an energy source for heterocyclic synthesis was herein investigated using condensation of 3-acetylcoumarin (1) with aromatic and heteroaromatic aldehydes to afford the corresponding aromatic chalcones (2a–j) and heteroaromatic chalcones (3a–e and 4a–e), respectively, in good to excellent yield within 1–3 min. The chemical structures were confirmed by analytical and spectral data. All the synthesized compounds were screened for their antibacterial activity and 3-{3-(4-dimethylaminophenyl)acryloyl}-2H-chromen-2-one (2i) was discovered to be the most active at minimum inhibitory concentration (MIC) value of 7.8 µg/m

    Ethyl 4-(2-fur­yl)-2-oxochroman-3-carboxyl­ate

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    The title compound, C16H14O5, was prepared from the reaction of 3-carbethoxy­coumarin with furan in the presence of AlCl3 as catalyst. In the crystal, inter­molecular C—H⋯O hydrogen-bonding inter­actions between four mol­ecules lead to a tetra­mer in the unit cell. The furan ring is anti­periplanar [C—C—C—O = 167.9 (13)°] and the ethoxy­carbonyl group is (−)anti­clinal [C—C—C—O = −128.6 (14)°] to the lactone ring
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