MicroRNAs in endometrial cancer

Endometrial cancer is a common malignant gynecological tumor, but there are few biomarkers that are useful for early and accurate diagnosis and few treatments other than surgery. However, use of microRNAs (miRNAs) that induces gene downregulation in cells may permit effective and minimally invasive diagnosis and treatment. In endometrial cancer cells, expression levels of miRNAs including miR-185, miR-210 and miR-423 are upregulated and those of miR-let7e, miR-30c and miR-221 are downregulated compared to normal tissues, and these miRNAs are involved in carcinogenesis, invasion and metastasis. miRNAs with expression changes such as miR-181b, miR-324-3p and miR-518b may be used as prognostic biomarkers and transfection of miR-152 may inhibit cancer growth. However, most current studies of miRNAs are at a basic level and further work is needed to establish clinical applications targeting miRNAs

ヨウゴキョウユ フクスウハイチ ト ダンセイヨウゴキョウユ シツモンシチョウサ カラ ノ ケントウ ダイニホウ

Yogo teachers practice health education widely to support healthy growth of children, which is purpose of school education.Through questionnaires for Yogo teachers of Mie prefecture, it came out that they wanted plural Yogo teachers system and didn\u27t deny appearance of male Yogo teachers in order to solve diverse health problems and practice health counseling actively.We studied about plural Yogo teachers system and male Yogo teacher to promote function of Yogo teacher through the questionnaires

ホケンカンリセンター ノ アリカタ

Recently, it is said that it has changed what health management center should be. Through all applicants be able to pass into colleges or universities now, if they don\u27t select them, it is considered that there are some students who need mental care.The consciousness for the purpose of student life is diverse and it is often necessary for students to counsel and manage closely.Then the viewpoint of this study depends on questionnaire and reputation about the "plural Yogo Teachers in a school" system, the adoption of a male Yogo teacher and emphasis of counseling.From the questionnaire and the user, most of the impressions about this center are easy to enter and talk to.Through this study, it is suggestive what should be the hearth management center and needs of counseling will become more important

Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire (JHEQ): a patient-based evaluation tool for hip-joint disease. The Subcommittee on Hip Disease Evaluation of the Clinical Outcome Committee of the Japanese Orthopaedic Association

AbstractBackgroundThe Japanese Orthopaedic Association Hip Score is widely used in Japan, but this tool is designed to reflect the viewpoint of health-care providers rather than that of patients. In gauging the effect of medical therapies in addition to clinical results, it is necessary to assess quality of life (QOL) from the viewpoint of patients. However, there is no tool evaluating QOL for Japanese patients with hip-joint disease.MethodsWith the aim of more accurately classifying QOL for Japanese patients with hip-joint disease, we prepared a questionnaire with 58 items for the survey derived from 464 opinions obtained from approximately 100 Japanese patients with hip-joint disease and previously devised evaluation criteria. In the survey, we collected information on 501 cases, and 402 were subjected to factor analysis. From this, we formulated three categories—movement, mental, and pain—each comprising 7 items, for a total of 21 items to be used as evaluation criteria for hip-joint function.ResultsThe Cronbach’s α coefficients for the three categories were 0.93, 0.93, and 0.95, respectively, indicating the high reliability of the evaluation criteria. The 21 items included some related to the Asian lifestyle, such as use of a Japanese-style toilet and rising from the floor, which are not included in other evaluation tools.ConclusionsThis self-administered questionnaire may become a useful tool in the evaluation of not only Japanese patients, but also of members of other ethnic groups who engage in deep flexion of the hip joint during daily activities

ヨウゴキョウユ ヨウ セイキョウイク ノ ドウコウ シツモンシチョウサ カラ ノ ケントウ ダイイッポウ

Social environments around children have been changed widely and issues of school have become more and more complex and divers. There are movement that parents and citizen need for teachers higher quality and education.In order to solve the health problem that contemporary children seriously have, we have to consider how to improve quality of Yogo teacher through expanding role and making education of Yogo teachers satisfactory.Then this study treats the trend of the education of Yogo teacher in our college and questioner about college education through incumbent students and Yogo teachers at the result of this research, it came out that they want four- years college. And promoting ability of nursing that is required for Yogo teacher is important issue in future

アメリカン・ボード宣教師文書 :同志社女学校女性宣教師を中心として 〈M. F. デントン書簡:訳および註〉（８）

翻

アメリカン・ボード宣教師文書 : 同志社女学校女性宣教師を中心として : M. F. デントン書簡訳および註 (7)

翻

アメリカン・ボード宣教師文書：同志社女学校女性宣教師を中心として〈M. F. デントン書簡：訳および註〉（10）

翻

Dialog of a Few Hours (Sukoku no taiwa)

https://digitalcommons.unf.edu/campus_art/1361/thumbnail.jp