A framework to coordinate web services in composition scenarios

This paper looks into the coordination of web services following their acceptance to participate in a composition scenario. We identify two types of behaviours associated with component web services: Operational and control behaviours. These behaviours are used to specify composite web services that are built upon component web services. In term of orchestration a composite web service could be either centralised or peer-to-peer. To support component/composite web services coordination per type of orchestration schema, various types of messages are exchanged between these web services. Experiments showing the use of these messages are reported in this paper as well. Copyright © 2010 Inderscience Enterprises Ltd

Attenuating Muscle Damage Biomarkers and Muscle Soreness After an Exercise-Induced Muscle Damage with Branched-Chain Amino Acid (BCAA) Supplementation:A Systematic Review and Meta-analysis with Meta-regression

Background: Branched-chain amino acid (BCAA) supplementation is one of the most popular strategies used by the general population and athletes to reduce muscle soreness and accelerate the recovery process of muscle damage biomarkers after an intense exercise or training session. Objectives: This systematic review and meta-analysis investigated the effects of BCAA supplementation on muscle damage biomarkers and muscle soreness after exercise-induced muscle damage (EIMD). Methods: The systematic literature search for randomized controlled trials was conducted using seven databases, up to September 13th, 2022. The eligibility criteria for selecting studies were as follows: studies performed on healthy active participants, using BCAA at least once, controlled with a placebo or control group, performing resistance or endurance exercises, and followed up at least once post-EIMD. The methodological quality of the studies was assessed using the “SIGN RCT checklist”. Random-effects meta-analyses were processed to compute the standardized mean difference (Hedges’ g). Meta-regression analyses were completed with daily and total dosage and supplementation as continuous moderator variables. Results: Of the 18 studies included in this meta-analysis, 13 were of high quality and five were of acceptable quality. Our results revealed BCAA supplementation elicits a significant effect on reducing creatine kinase (CK) levels immediately (g = − 0.44; p = 0.006) and 72 h (g = − 0.99; p = 0.002), but not 24 h, 48 h, and 96 h post-EIMD. Additionally, a significant effect on delayed onset of muscle soreness (DOMS) was identified at 24 h (g = − 1.34; p < 0.001), 48 h (g = − 1.75; p < 0.001), 72 h (g = − 1.82; p < 0.001), and 96 h (g = − 0.82; p = 0.008), but not immediately post-EIMD. No significant effect was found on lactate dehydrogenase (LDH) levels at any time point. Meta-regression indicated higher daily and total dosages of BCAA, and longer supplementation periods were related to the largest beneficial effects on CK (total dosage and supplementation period) at 48 h, and on DOMS at 24 h (only daily dosage). Conclusion: The overall effects of BCAA supplementation could be considered useful for lowering CK and DOMS after EIMD, but not LDH. The longer supplementation period prior to the EIMD could be more effective for CK and DOMS reduction

The effect of tobacco, XPC, ERCC2 and ERCC5 genetic variants in bladder cancer development

<p>Abstract</p> <p>Background</p> <p>In this work, we have conducted a case-control study in order to assess the effect of tobacco and three genetic polymorphisms in <it>XPC, ERCC2 and ERCC5 </it>genes (rs2228001, rs13181 and rs17655) in bladder cancer development in Tunisia. We have also tried to evaluate whether these variants affect the bladder tumor stage and grade.</p> <p>Methods</p> <p>The patients group was constituted of 193 newly diagnosed cases of bladder tumors. The controls group was constituted of non-related healthy subjects. The rs2228001, rs13181 and rs17655 polymorphisms were genotyped using a polymerase chain reaction-restriction fragment length polymorphism technique.</p> <p>Results</p> <p>Our data have reported that non smoker and light smoker patients (1-19PY) are protected against bladder cancer development. Moreover, light smokers have less risk for developing advanced tumors stage. When we investigated the effect of genetic polymorphisms in bladder cancer development we have found that ERCC2 and ERCC5 variants were not implicated in the bladder cancer occurrence. However, the mutated homozygous genotype for XPC gene was associated with 2.09-fold increased risk of developing bladder cancer compared to the control carrying the wild genotype (p = 0.03, OR = 2.09, CI 95% 1.09-3.99). Finally, we have found that the XPC, ERCC2 and ERCC5 variants don't affect the tumors stage and grade.</p> <p>Conclusion</p> <p>These results suggest that the mutated homozygous genotype for XPC gene was associated with increased risk of developing bladder. However we have found no association between rs2228001, rs13181 and rs17655 polymorphisms and tumors stage and grade.</p

The effect of Opuntia ficus‐indica juice supplementation on oxidative stress, cardiovascular parameters, and biochemical markers following yo‐yo Intermittent recovery test

The aim of the study was to investigate the effect of a flavonoid‐rich fresh fruit juice on cardiovascular, oxidative stress, and biochemical parameters during the yo‐yo intermittent recovery test (YYIRT). Twenty‐two healthy males subjects participated in this study divided into two groups: An experimental group (EG: n = 11) who consumed the antioxidant supplement and a control group (CG: n = 11). All participants performed two test sessions at 07:00 hr before and after 2 weeks of supplementation with Opuntia ficus‐indica juice. Blood samples were taken before (P1) and immediately (P2) after the YYIRT. Our results showed that following the 2,2‐diphenyl‐1‐ picrylhydrazyl (DPPH●) test, the Opuntia ficus‐indica juice has an antioxidant capacity for capturing free radicals (p &lt; .05) and reducing oxidative stress related to exercise. Concerning biochemical and cardiovascular parameters, our results showed a significant increase on total cholesterol (TC) (p &lt; .01), triglycerides (TG) (p &lt; .05), high‐density lipoprotein (HDL) (p &lt; .01), low‐density lipoprotein (LDL) (p &lt; .01), creatine kinase (CK) (p &lt; .01), lactate deshydrogenase (LDH) (p &lt; .01), glucose (GLC) (p &lt; .01), systolic (SBP), and diastolic blood pressure (DBP) (p &lt; .01) immediately after exercise. However, TC (p &lt; .05), TG (p &lt; .05) and LDL (p &lt; .05), the maximal heart rate (HRmax), the CK (p &lt; .05), and LDH (p &lt; .01) as well as the malondialdehyde (MDA) (p &lt; .01) demonstrated a significant decrease after supplementation of Opuntia ficus‐indica juice before and immediately after YYIRT. However, no significant effect on HDL (p &gt; .05), GLC (p &gt; .05) levels nor the SBP and DBP (p &gt; .05) was observed after supplementation with Opuntia ficus‐indica juice. The supplementation leads to an improvement on YYIRT performance (The total distance covered during the YYIRT, VO2max, VMA) and the rating of perceived exertion (RPE). Opuntia ficus‐indica juice has a potent antioxidant activity that reduces total and LDL‐cholesterol with only a moderate lowering of HDL‐cholesterol and oxidative stress. Moreover, supplementation decreases muscle damage caused by the endurance exercise

Web services synchronization in composition scenarios: The centralized view

This paper discusses Web services synchronization at the composition level. Synchronization aims at assisting independent parties coordinate their actions and thus, avoid conflicts. Our previous work on synchronization primarily focussed on the component level and shed the light on two types of behaviors related to specifying Web services. The operational behavior defines the business logic that underpins the functioning of a Web service, and the control behavior regulates the execution progress of this operational behavior by stating the actions to carry out and the constraints to put on this progress. Operational and control behaviors continue to be used to specify composite Web services with respect to the orchestration schemas that these composite Web services have to comply with whether centralized or peer-to-peer. As a result, various types of messages to achieve synchronization are developed per type of orchestration schema. Experiments showing the use of these messages are reported in this paper as well. Copyright 2009 ACM

Does Opuntia ficus-indica Juice Supplementation Improve Biochemical and Cardiovascular Response to a 6-Minute Walk Test in Type 2 Diabetic Patients?

Background and objectives: The purpose of this study was to evaluate the effect of Opuntia ficus-indica juice (OFIJ) on performance and biochemical and physiological responses to a 6 min walking test (6MWT) in diabetic patients. Materials and Methods: Twenty diabetic patients performed a 6MWT at 07:00 h. During each test session, they were asked to drink 70 mL/day of natural OFIJ or placebo (PLA) for 4 days. Results: the results showed that cardiovascular parameters increased significantly after the 6MWT under both conditions. While, cortisol, HbA1c, cholesterol total (CT), triglycerides (TG), as well as low-density lipoprotein (LDL) were not modified between without and with supplementation. Likewise, no significant variation in performance was observed for PLA and OFIJ (p &gt; 0.05). The cardiovascular parameters (heart rate max (HRmax), diastolic blood pressure (DBP), and systolic blood pressure (SBP)), lipid profile (CT, TG, LDL, and high-density lipoprotein HDL), hormonal parameters (insulin and glucagon), HbA1c and lactate ([La]) did not present any significant modification either between PLA or OFIJ (p &gt; 0.05). Muscle-damage markers (creatine kinase (CK) and lactate dehydrogenase (LDH)], cortisol, and liver parameters (i.e., oxidative stress marker, &gamma;GT, and total bilirubin) as well as glucose (GLC) were affected by supplementation (p &lt; 0.05) before and after the 6MWT, but this change was significant only for OFIJ (p &lt; 0.05). Conclusion: OFIJ had an antioxidant capacity, improved performance of the 6MWT, and reduced muscle-damage markers and glucose level in type 2 diabetic patients