51 research outputs found

    TO THE PROBLEM OF STUDYING THE ETHICAL CHARACTERISTICS OF THE PERSON

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    Purposes: The crisis in modern humanitarian science testifies to the need to search for a new approach that goes beyond the boundaries of the natural-science approach, which in its turn involves addressing to the origins of our culture, expanding the categorical apparatus and methodological basis of psychology. In individual consciousness, the spiritual crisis is expressed in the loss of the ideals of life. Therefore, at the present stage of the development of society, the need for a philosophical and psychological analysis of spiritual and moral ideas and their role in the formation of the individual is felt with particular severity. Methodology: In the framework of the activity approach embodied in the works of S. L. Rubinstein, the main provisions were formulated, which are of special methodological importance for the solution of this problem. In particular, these are provisions on the study of the human psyche through its manifestations in the main types of activity and the influence on the activities of external causes, not directly, but indirectly, through its internal, psychological conditions. Results: This article is devoted to the description of the results of an empirical study carried out from the position of the activity approach and aimed at revealing the level of ethical behavior of adolescence and youth ages. The urgency of the study is due to the fact that the tendency of the transition from the theoretical-descriptive to the experimental-developing technology of research of ethical characteristics is clearly manifested in the work. Implications/Applications: This article could be practical in predicting the problems regarding the study of Ethical Characteristics of person and help the audience to broaden their information in this vein. Novelty/Originality: In one case, the individual in the process of communicating with other people, assimilates universal values, the experience of moral relations, develops beliefs and moral ideals, in the other can under the influence of communication become attached to completely opposite values, degrade morall

    Adequate hemodynamic response threshold in athletes at graduated physical loads

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    Objective of the study was to identify the adequate hemodynamic response threshold in athletes grouped by different cardiorespiratory system adaptation types and exposed to graduated physical loads. Graduated intensity (50 W to 200 W) cycle ergometer tests were used to apply the varying physical loads, with no rest breaks in the process. The subject athletes were grouped by different cardiorespiratory adaptation types, with the loads up to 200 W in the cycle ergometer step tests being applied for the above athletes' grouping. Based on the tests, the subjects were grouped into 5 groups based on the following cardiorespiratory system adaptation types: chronotopic, inotropic, respiratory, chronotropicrespiratory and the inotropic-respiratory type. Subject to the study were 18-35 years old men athletes (n=59) engaged in different sports and having a variety of sport qualifications from Sport Masters down to mass Class Athletes. The adequate hemodynamic response threshold was found to depend on the cardiorespiratory system adaptation types and load intensities. The higher was the adequate hemodynamic response threshold, the higher were the functional and reserve capacities of the athletes as verified by the SBV (specific blood volume) rate variations under the graduated loads. Therefore, the adequate hemodynamic response threshold may be applied as a body functional and reserve capacity indicator

    ЙСмСнский ΠΎΠΏΡ‹Ρ‚ Π΄Π΅Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ исламизма

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    The ongoing armed conflict in Yemen between the forces of ousted President M. Hadi, supported by the coalition units of the Gulf monarchies led by Saudi Arabia and the Houthi group Ansar Allah, has a destabilizing effect on the entire Arabian Peninsula as a whole. In this regard, the creation of a deradicalization program and its implementation will help to solve several main tasks. First, to change the worldview of members of Islamist groups and movements from radical to moderate. Secondly, it will significantly reduce the level of instability in the Middle East region, where the majority of armed conflicts is conducted under religious slogans. The main focus of this study is on measures to counter radical Islamism, which were taken by the Yemeni authorities before and after the events of the Arab Spring. At the initial stage, the Yemeni administration’s use of the de-radicalization program showed impressive results. However, the ongoing fighting, as well as the reluctance of the Yemeni elite to Fund the deradicalization programme, led to its closure. The subsequent events of the Arab Spring brought additional instability to the domestic political situation in Yemen. Attempts to revive the program of deradicalization by the new Yemeni administration have failed. In general, the work done by the Yemeni authorities to deradicalize Islamism has demonstrated the ability to use non-violent methods of struggle, but their use is associated with serious financial investments, which the Yemeni state is not yet able to make due to the difficult financial situation caused by the prolonged armed conflict.Π Π°Π±ΠΎΡ‚Π° посвящСна ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΠ΅ Π΄Π΅Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ исламизма Π² Π™Π΅ΠΌΠ΅Π½Π΅ Π΄ΠΎ ΠΈ послС событий «арабской вСсны». На Π½Π°Ρ‡Π°Π»ΡŒΠ½ΠΎΠΌ этапС ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΠ° Π΄Π΅Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ, проводимая йСмСнской администрациСй, ΠΏΠΎΠΊΠ°Π·Π°Π»Π° Π²ΠΏΠ΅Ρ‡Π°Ρ‚Π»ΡΡŽΡ‰ΠΈΠ΅ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. Однако Π½Π΅ΡΡ‚Π°Π±ΠΈΠ»ΡŒΠ½ΠΎΡΡ‚ΡŒ Π²Π½ΡƒΡ‚Ρ€Π΅Π½Π½Π΅ΠΉ ситуации, Π° Ρ‚Π°ΠΊΠΆΠ΅ Π½Π΅ΠΆΠ΅Π»Π°Π½ΠΈΠ΅ йСмСнской элиты Ρ„ΠΈΠ½Π°Π½ΡΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΡƒ ΠΏΡ€ΠΈΠ²Π΅Π»ΠΈ ΠΊ Π΅Π΅ Π·Π°ΠΊΡ€Ρ‹Ρ‚ΠΈΡŽ. Π­Ρ‚ΠΎΠΌΡƒ ΠΎΠ±ΡΡ‚ΠΎΡΡ‚Π΅Π»ΡŒΡΡ‚Π²Ρƒ способствовало ΠΈ Ρ‚ΠΎ, Ρ‡Ρ‚ΠΎ Π² ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠ΅ администрации ΠΏΠΎ Π±ΠΎΡ€ΡŒΠ±Π΅ с Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΡŒΠ½Ρ‹ΠΌΠΈ Π³Ρ€ΡƒΠΏΠΏΠΈΡ€ΠΎΠ²ΠΊΠ°ΠΌΠΈ ΠΏΡ€ΠΈΠΎΡ€ΠΈΡ‚Π΅Ρ‚Π½Ρ‹ΠΌ Π±Ρ‹Π»ΠΎ ΡΠΎΠ²Π΅Ρ€ΡˆΠ΅Π½ΡΡ‚Π²ΠΎΠ²Π°Π½ΠΈΠ΅ силового Π°ΠΏΠΏΠ°Ρ€Π°Ρ‚Π°. ΠŸΠΎΠΏΡ‹Ρ‚ΠΊΠΈ Π½ΠΎΠ²ΠΎΠΉ йСмСнской власти Π²ΠΎΠ·Ρ€ΠΎΠ΄ΠΈΡ‚ΡŒ ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΡƒ Π΄Π΅Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ послС событий «арабской вСсны» ΠΎΠ±Π΅Ρ€Π½ΡƒΠ»ΠΈΡΡŒ ΠΏΡ€ΠΎΠ²Π°Π»ΠΎΠΌ. Π’ Ρ†Π΅Π»ΠΎΠΌ продСланная йСмСнскими властями Ρ€Π°Π±ΠΎΡ‚Π° ΠΏΠΎ Π΄Π΅Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ исламизма продСмонстрировала ΡƒΠΌΠ΅Π½ΠΈΠ΅ ΠΏΡ€ΠΈΠΌΠ΅Π½ΡΡ‚ΡŒ нСсиловыС ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹ Π±ΠΎΡ€ΡŒΠ±Ρ‹, ΠΎΠ΄Π½Π°ΠΊΠΎ ΠΈΡ… использованиС связано с ΡΠ΅Ρ€ΡŒΠ΅Π·Π½Ρ‹ΠΌΠΈ финансовыми влоТСниями, Π½Π° ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ йСмСнскоС государство ΠΏΠΎΠΉΡ‚ΠΈ ΠΏΠΎΠΊΠ° Π½Π΅ ΠΌΠΎΠΆΠ΅Ρ‚ ΠΈΠ·-Π·Π° тяТСлой финансовой ситуации, Π²Ρ‹Π·Π²Π°Π½Π½ΠΎΠΉ Π·Π°Ρ‚ΡΠ½ΡƒΠ²ΡˆΠΈΠΌΡΡ Π²ΠΎΠΎΡ€ΡƒΠΆΠ΅Π½Π½Ρ‹ΠΌ ΠΊΠΎΠ½Ρ„Π»ΠΈΠΊΡ‚ΠΎΠΌ

    «Арабская вСсна» ΠΊΠ°ΠΊ Ρ„Π°ΠΊΡ‚ΠΎΡ€ возникновСния салафитских ΠΏΠ°Ρ€Ρ‚ΠΈΠΉ Π½Π° Π‘Π»ΠΈΠΆΠ½Π΅ΠΌ ВостокС ΠΈ Π² Π‘Π΅Π²Π΅Ρ€Π½ΠΎΠΉ АфрикС

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    The article is devoted to the analysis of Salafi Islamism. Conservative Salafi Islamism during the events of the Arab spring received a new development. In particular, the fall of authoritarian regimes and the beginning of the democratic process in the Middle East and North Africa led to the creation of Salafi political parties. The Salafi sts believed, that in a favorable political environment, they would be able to defend their legal status and gain some privileges through participating in parliamentary elections. However, the creation of parties has deepened internal divisions within the Salafi movements. In particular, there were supporters among the Salafi sts, who defended the combination of student and political activities against those who considered participation in the political struggle as a temporary tactical action. The result of the disagreement was the emergence of a reformist movement, that began to see participation in politics as a tool for strengthening the position of the Salafi st movement.Π‘Ρ‚Π°Ρ‚ΡŒΡ посвящСна ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΠ΅ ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠ·Π°Ρ†ΠΈΠΈ салафизма. ΠšΠΎΠ½ΡΠ΅Ρ€Π²Π°Ρ‚ΠΈΠ²Π½Ρ‹ΠΉ салафитский исламизм Π²Β ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ событий «арабской вСсны» ΠΏΠΎΠ»ΡƒΡ‡ΠΈΠ» Π½ΠΎΠ²ΠΎΠ΅ Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅. В частности, ΠΏΠ°Π΄Π΅Π½ΠΈΠ΅ Π°Π²Ρ‚ΠΎΡ€ΠΈΡ‚Π°Ρ€Π½Ρ‹Ρ… Ρ€Π΅ΠΆΠΈΠΌΠΎΠ² ΠΈΒ Π½Π°Ρ‡Π°Π²ΡˆΠΈΠΉΡΡ дСмократичСский процСсс в странах Π‘Π»ΠΈΠΆΠ½Π΅Π³ΠΎ Востока ΠΈΒ Π‘Π΅Π²Π΅Ρ€Π½ΠΎΠΉ Африки ΠΏΡ€ΠΈΠ²Π΅Π»ΠΈ ΠΊΒ Ρ‚ΠΎΠΌΡƒ, Ρ‡Ρ‚ΠΎ салафитскиС двиТСния стали ΡΠΎΠ·Π΄Π°Π²Π°Ρ‚ΡŒ политичСскиС ΠΏΠ°Ρ€Ρ‚ΠΈΠΈ. Π‘Π°Π»Π°Ρ„ΠΈΡ‚Ρ‹ считали, Ρ‡Ρ‚ΠΎ в условиях благоприятной политичСской ΠΊΠΎΠ½ΡŠΡŽΠ½ΠΊΡ‚ΡƒΡ€Ρ‹ ΠΈΠΌ удастся ΠΎΡ‚ΡΡ‚ΠΎΡΡ‚ΡŒ свой ΠΏΡ€Π°Π²ΠΎΠ²ΠΎΠΉ статус ΠΈΒ ΠΏΠΎΠ»ΡƒΡ‡ΠΈΡ‚ΡŒ Π½Π΅ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ ΠΏΡ€ΠΈΠ²ΠΈΠ»Π΅Π³ΠΈΠΈ Ρ‡Π΅Ρ€Π΅Π· участиС в парламСнтских Π²Ρ‹Π±ΠΎΡ€Π°Ρ…. Однако созданиС ΠΏΠ°Ρ€Ρ‚ΠΈΠΉ ΠΏΡ€ΠΈΠ²Π΅Π»ΠΎ ΠΊΒ ΡƒΠ³Π»ΡƒΠ±Π»Π΅Π½ΠΈΡŽ разногласий Π²Π½ΡƒΡ‚Ρ€ΠΈ самих салафитских Π΄Π²ΠΈΠΆΠ΅Π½ΠΈΠΉ. В частности, салафиты Ρ€Π°Π·Π΄Π΅Π»ΠΈΠ»ΠΈΡΡŒ Π½Π° Ρ‚Π΅Ρ…, ΠΊΡ‚ΠΎ отстаивал совмСщСниС проповСдничСской и политичСской Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ, ΠΈΒ Ρ‚Π΅Ρ…, кто рассматривал участиС в политичСской Π±ΠΎΡ€ΡŒΠ±Π΅ в качСствС Π²Ρ€Π΅ΠΌΠ΅Π½Π½ΠΎΠΉ тактичСской Π°ΠΊΡ†ΠΈΠΈ. Π˜Ρ‚ΠΎΠ³ΠΎΠΌ разногласий стало появлСниС рСформистского направлСния, Ρ€Π°ΡΡΠΌΠ°Ρ‚Ρ€ΠΈΠ²Π°ΡŽΡ‰Π΅Π³ΠΎ участиС Π²Β ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠ΅ ΠΊΠ°ΠΊ инструмСнт для укрСплСния ΠΏΠΎΠ·ΠΈΡ†ΠΈΠΉ салафитского двиТСния

    Qatar and Turkey in the Struggle for Influence in the Republic of Sudan

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    ΠšΠ°Ρ‚Π°Ρ€ΡΠΊΠΎ-Ρ‚ΡƒΡ€Π΅Ρ†ΠΊΠΈΠΉ альянс Π² ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ событий «арабской вСсны» бросил бСспрСцСдСнтный Π²Ρ‹Π·ΠΎΠ² ΡƒΡΠΈΠ»ΠΈΠ²Π°ΡŽΡ‰Π΅ΠΉΡΡ ΠΌΠΎΡ‰ΠΈ Баудовской Аравии Π² арабском Ρ€Π΅Π³ΠΈΠΎΠ½Π΅. Π­Ρ‚ΠΎ ΠΏΡ€ΠΎΡΠ²ΠΈΠ»ΠΎΡΡŒ Π²ΠΎ Π²ΠΌΠ΅ΡˆΠ°Ρ‚Π΅Π»ΡŒΡΡ‚Π²Π΅ Анкары ΠΈ Π”ΠΎΡ…ΠΈ Π²ΠΎ внутриполитичСскиС Π΄Π΅Π»Π° Π±ΠΎΠ»ΡŒΡˆΠΈΠ½ΡΡ‚Π²Π° государств рассматриваСмого Ρ€Π΅Π³ΠΈΠΎΠ½Π°. Однако эта Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ Π²Ρ‹Π·Π²Π°Π»Π° ΠΎΡ‚Π²Π΅Ρ‚Π½Ρ‹Π΅ дСйствия со стороны Π­Ρ€-Рияда, ΡΡ‚Ρ€Π΅ΠΌΠΈΠ²ΡˆΠ΅Π³ΠΎΡΡ Π½ΠΈΠ²Π΅Π»ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ Π½ΠΎΠ²ΡƒΡŽ ΡƒΠ³Ρ€ΠΎΠ·Ρƒ Π² Π»ΠΈΡ†Π΅ ΠšΠ°Ρ‚Π°Ρ€Π° ΠΈ Π’ΡƒΡ€Ρ†ΠΈΠΈ.During the Arab Spring, Qatari-Turkish alliance threw an unprecedented challenge to the growing power of Saudi Arabia in the Arab region. This was manifested in the intervention of Ankara and Doha in the internal political affairs of most States of the Arab region. However, such activity caused retaliatory actions on the part of Riyadh, which sought to neutralize the new threat in the face of Qatar and Turkey

    The disorders of verbal communication in patients with diabetes mellitus type 2: Causes and treatment

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    Β© Medwell Journals, 2015. The study describes the decline of verbal and communicative functions in patients with diabetes mellitus type 2. The researchers reveal the causes of verbal communication impairment and describe some methods of its estimation (baseline neurocognitive tests, Mini-Mental State Examination and Montreal Cognitive Assessment) as well as the research outcomes. We discuss certain problems of verbal contact in these patients from neurological, neurolinguistic and neuropsychological points of view. Verbal communication disorders evidently declare themselves through short and long-term verbal memory impairments and language attention decline. They negatively affect cognitive functions, significantly reducing the patient’s capability for adequate communication. The researchers suggest some ways of medical and linguistic assistance to patients with diabetes mellitus type 2 in clinical practice. They accentuate the need for timely diagnostics and help for these patients. The research was conducted at Department of Neurology No. 1, Republic Clinical Hospital No. 2 (Kazan, Russia), the clinical base of Kazan Federal University

    ΠšΠ°Ρ‚Π°Ρ€ΡΠΊΠΎ-Ρ‚ΡƒΡ€Π΅Ρ†ΠΊΠΈΠΉ альянс Π² Π±ΠΎΡ€ΡŒΠ±Π΅ Π·Π° лидСрство Π² Π‘ΠΎΠΌΠ°Π»ΠΈ

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    The article examines the struggle of the Qatari- Turkish alliance for regional leadership in the Federal Republic of Somalia. The analysis revealed that the foreign policy activity of Turkey and Qatar in Somalia began during the events of the Arab Spring. Ankara and Doha used diplomatic, military and fi nancial instruments to strengthen their infl uence in the country. Moreover, Qatari money played an important role in promoting pro-qatari candidates to power during the 2012 and 2017 presidential elections. However, the eff orts of the Turkish- Qatari alliance to strengthen its position in Somalia have clashed with the interests of the Saudi- Emirati bloc seeking regional dominance. On the other hand, the inability to close the main cooperation with the central government in Somalia forced the UAE to support such autonomous regions as Somaliland, thereby intensifying the destabilization processes in the country.Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ рассматриваСтся Π±ΠΎΡ€ΡŒΠ±Π° катарско- Ρ‚ΡƒΡ€Π΅Ρ†ΠΊΠΎΠ³ΠΎ альянса Π·Π° Ρ€Π΅Π³ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ΅ лидСрство Π² Π€Π΅Π΄Π΅Ρ€Π°Ρ‚ΠΈΠ²Π½ΠΎΠΉ РСспубликС Π‘ΠΎΠΌΠ°Π»ΠΈ. Π’ Ρ…ΠΎΠ΄Π΅ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½Π½ΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π° выясняСтся, Ρ‡Ρ‚ΠΎ Π²Π½Π΅ΡˆΠ½Π΅ΠΏΠΎΠ»ΠΈΡ‚ΠΈΡ‡Π΅ΡΠΊΠ°Ρ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ Π’ΡƒΡ€Ρ†ΠΈΠΈ ΠΈ ΠšΠ°Ρ‚Π°Ρ€Π° Π² Π‘ΠΎΠΌΠ°Π»ΠΈ Π½Π°Ρ‡Π°Π»Π°ΡΡŒ Π² ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ событий «арабской вСсны». Для усилСния своСго влияния Π² странС Анкара ΠΈ Π”ΠΎΡ…Π° использовали дипломатичСский, Π²ΠΎΠ΅Π½Π½Ρ‹ΠΉ ΠΈ финансовый инструмСнты. Π‘ΠΎΠ»Π΅Π΅ Ρ‚ΠΎΠ³ΠΎ, катарскиС дСньги сыграли Π²Π°ΠΆΠ½ΡƒΡŽ Ρ€ΠΎΠ»ΡŒ Π² ΠΏΡ€ΠΎΠ΄Π²ΠΈΠΆΠ΅Π½ΠΈΠΈ ΠΊ власти прокатарских ΠΊΠ°Π½Π΄ΠΈΠ΄Π°Ρ‚ΠΎΠ² Π² ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ прСзидСнтских Π²Ρ‹Π±ΠΎΡ€ΠΎΠ² 2012 ΠΈ 2017 Π³Π³. Однако усилия Ρ‚ΡƒΡ€Π΅Ρ†ΠΊΠΎ- катарского альянса ΠΏΠΎ ΡƒΠΊΡ€Π΅ΠΏΠ»Π΅Π½ΠΈΡŽ своих ΠΏΠΎΠ·ΠΈΡ†ΠΈΠΉ Π² Π‘ΠΎΠΌΠ°Π»ΠΈ ΡΡ‚ΠΎΠ»ΠΊΠ½ΡƒΠ»ΠΈΡΡŒ с интСрСсами саудовско- эмиратского Π±Π»ΠΎΠΊΠ°, стрСмящСгося ΠΊ Ρ€Π΅Π³ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠΌΡƒ Π΄ΠΎΠΌΠΈΠ½ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΡŽ. Но Π½Π΅ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡ‚ΡŒ Π·Π°ΠΌΠΊΠ½ΡƒΡ‚ΡŒ Π½Π° сСбС основноС сотрудничСство с Ρ†Π΅Π½Ρ‚Ρ€Π°Π»ΡŒΠ½Ρ‹ΠΌ ΠΏΡ€Π°Π²ΠΈΡ‚Π΅Π»ΡŒΡΡ‚Π²ΠΎΠΌ Π‘ΠΎΠΌΠ°Π»ΠΈ, Π²Ρ‹Π½ΡƒΠ΄ΠΈΠ»ΠΎ ОАЭ ΠΏΠΎΠ΄Π΄Π΅Ρ€ΠΆΠΈΠ²Π°Ρ‚ΡŒ Ρ‚Π°ΠΊΠΈΠ΅ Π°Π²Ρ‚ΠΎΠ½ΠΎΠΌΠ½Ρ‹Π΅ Ρ€Π°ΠΉΠΎΠ½Ρ‹, ΠΊΠ°ΠΊ Π‘ΠΎΠΌΠ°Π»ΠΈΠ»Π΅Π½Π΄, Ρ‚Π΅ΠΌ самым усиливая дСстабилизационныС процСссы Π² самом Π‘ΠΎΠΌΠ°Π»ΠΈ

    Predictors of In-Hospital Mortality Among Patients with COVID-19 Related Stroke

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    Introduction. COVID-19-related stroke is associated with a significantly higher mortality than COVID-19 or stroke alone. Mechanisms underlying the increased mortality of patients with stroke and COVID-19 should be thoroughly studied. Objective: to analyze predictors of hospital mortality associated with COVID-19-related stroke. Materials and methods. We retrospectively analyzed 1,386 cases of COVID-19-related stroke reported by an infectious diseases inpatient clinic in 2020. We studied clinical, laboratory, and instrumental parameters in patients with different outcomes. Logistic regression was used to identify independent predictors of mortality. Results. 539 (38.9%) patients died during their hospital stay, with 437 (38.0%) deaths from ischemic stroke and 102 (42.7%) deaths from hemorrhagic stroke (p = 0.0001). Independent predictors of mortality associated with COVID-19-related stroke included age, neurological deficit severity measured by NIHSS, COVID-19 severity, and laboratory parameters including white blood cell count, creatinine, glucose, and D-dimer blood levels. Discussion. The results of logistic regression analysis were able to explain only 41% of the variability in hospital deaths among patients with stroke associated with COVID-19. Conclusion. Hospital mortality in patients with COVID-19-related stroke is associated with severity of inflammatory response, impaired coagulation, age, neurological deficit severity, and somatic comorbidities

    Induction of Apoptosis of Tumor Cells by Oligochitosans (Short Chain Chitosans)

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    Β© 2016, Springer Science+Business Media New York.An induction of apoptosis by short chain chitosans in human lung carcinoma A549 cells and cow embryonic lung cells was studied. Seventeen well-defined oligochitosans with wide range of molecular weights, from 5.5 to 46.7Β kDa, were used in this study. The experiments showed that three oligochitosans with molecular weight 6.1, 7.7, and 9.0Β kDa notably induced the high level of apoptosis of human lung carcinoma A549 cells. It presented a dose-dependent manner, and the apoptotic rate amounted to about 29–50Β % after treatment with 200Β ΞΌg/ml oligochitosans for 24Β h for A549 cells and 7–17Β % for LEC cells in the same conditions. The results obtained show that the oligochitosans are more active in inducing apoptosis and in decreasing viability in A549 cells than LEC, which suggests that it could be a potential chemotherapeutic drug

    Π£ΡΡ‚ΠΎΠΉΡ‡ΠΈΠ²ΠΎΡΡ‚ΡŒ яиц Π³Π΅Π»ΡŒΠΌΠΈΠ½Ρ‚ΠΎΠ² ΠΊ нСблагоприятным физичСским, химичСским ΠΈ биологичСским Ρ„Π°ΠΊΡ‚ΠΎΡ€Π°ΠΌ ΠΎΠΊΡ€ΡƒΠΆΠ°ΡŽΡ‰Π΅ΠΉ срСды (ΠΎΠ±Π·ΠΎΡ€ Π»ΠΈΡ‚Π΅Ρ€Π°Ρ‚ΡƒΡ€Ρ‹)

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    Objective of research: The purpose of this paper is the analysis of literature sources on the resistance of some helminth species to unfavorable physical, chemical and biological factors of the environment. Materials and methods: Literature sources that describe the resistance of some species of helminth eggs to unfavorable physical, chemical and biological environmental factors were analyzed. Results and discussion: Nematode eggs ( Parascaris equorum and Ascaris suum) die in water at the temperature of 60 Β°Π‘ for 25-30 sec., at 70-80 Β°Π‘ - for 2 sec.; Ascaridia galli eggs at 45 Β°Π‘ - for 2 hr., at 55 Β°Π‘ - for 2 sec.; Ascaris lumbricoides eggs at 50 Β°Π‘ - for 5 min., at 55-60 Β°Π‘ - for 5 sec. and at 65 Β°Π‘ - for 2 sec. Drying of P. equorum eggs at temperature of 30-36 Β°Π‘ leads to their death after 3-5 days. P. equorum and Ascaris eggs die after 15 min. at temperature of 70 Β°Π‘. Low air temperatures have different effects on helminth eggs. At temperatures below zero, the metabolic processes and development of P. equorum eggs stop. Concentrated sulfuric, chlorohydric, nitric, carbolic acids as well as creolin, bleach powder, dichloroethane, cresol are mostly used for elimination of helminth eggs. 3 and 5% solutions of disinfectants Β«Bior-NΒ», Β«VeltorganΒ» and Β«AmocideΒ» can be used for a 100% inhibition of development of ascaris eggs. For the elimination of Ascaris suum eggs, a method of wastewater treatment with the use of phytoplankton Clorella vulgaris and Scenedesmys obliguus has been suggested. Wastewater treated in bioponds is completely cleaned from helminth eggs. Harmful effects of rhizosphere of marigold, pot marigold, barley and millet on helminth eggs were determined. Various protozoa also affect the viability of helminth eggs. So, Amoeba verrucosa can intake ascaris eggs and free larvae released from eggs. Predatory infusoria Bursaria truncatula, Stylonichia mytilus and Stentor sp. intake and ascaris eggs, coracidia of Pseudophyllidea and miracidia of Fasciola hepatica , and completely digest them within 24-72 hrs. Oligochaeta, Bedford’s flatworms (Pseudobiceros bedfordi), aquatic insects, Crustacea and mollusks take part in the elimination of helminth eggs.ЦСль исслСдования - ΡΠ΄Π΅Π»Π°Ρ‚ΡŒ Π°Π½Π°Π»ΠΈΠ· Π»ΠΈΡ‚Π΅Ρ€Π°Ρ‚ΡƒΡ€Π½Ρ‹Ρ… источников ΠΏΠΎ устойчивости яиц Π½Π΅ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… Π²ΠΈΠ΄ΠΎΠ² Π³Π΅Π»ΡŒΠΌΠΈΠ½Ρ‚ΠΎΠ² ΠΊ нСблагоприятным физичСским, химичСским ΠΈ биологичСским Ρ„Π°ΠΊΡ‚ΠΎΡ€Π°ΠΌ ΠΎΠΊΡ€ΡƒΠΆΠ°ΡŽΡ‰Π΅ΠΉ срСды. ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. ΠŸΡ€ΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Π½Ρ‹ Π»ΠΈΡ‚Π΅Ρ€Π°Ρ‚ΡƒΡ€Π½Ρ‹Π΅ источники ΠΏΠΎ ΠΈΠ·ΡƒΡ‡Π΅Π½ΠΈΡŽ устойчивости яиц Π½Π΅ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… Π²ΠΈΠ΄ΠΎΠ² Π³Π΅Π»ΡŒΠΌΠΈΠ½Ρ‚ΠΎΠ² ΠΊ нСблагоприятным физичСским, химичСским ΠΈ биологичСским Ρ„Π°ΠΊΡ‚ΠΎΡ€Π°ΠΌ ΠΎΠΊΡ€ΡƒΠΆΠ°ΡŽΡ‰Π΅ΠΉ срСды. Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΈ обсуТдСниС. Π—Π° 2 с ΠΏΠΎΠ³ΠΈΠ±Π°ΡŽΡ‚ Π² Π²ΠΎΠ΄Π΅ яйца Parascaris equorum ΠΈ Ascaris suum, Ascaridia galli, A. lumbricoides ΠΏΡ€ΠΈ Ρ‚Π΅ΠΌΠΏΠ΅Ρ€Π°Ρ‚ΡƒΡ€Π΅ соотвСтствСнно 70-80 Β°Π‘, 55, 65 Β°Π‘. Π’Ρ‹ΡΡƒΡˆΠΈΠ²Π°Π½ΠΈΠ΅ яиц P. equorum ΠΏΡ€ΠΈ Ρ‚Π΅ΠΌΠΏΠ΅Ρ€Π°Ρ‚ΡƒΡ€Π΅ 30-36 Β°Π‘ ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ ΠΈΡ… ΠΊ Π³ΠΈΠ±Π΅Π»ΠΈ Ρ‡Π΅Ρ€Π΅Π· 3-5 сут. ΠŸΡ€ΠΈ Ρ‚Π΅ΠΌΠΏΠ΅Ρ€Π°Ρ‚ΡƒΡ€Π΅ 70 Β°Π‘ яйца P. equorum ΠΈ аскаридий ΠΏΠΎΠ³ΠΈΠ±Π°ΡŽΡ‚ Ρ‡Π΅Ρ€Π΅Π· 15 ΠΌΠΈΠ½. НизкиС Ρ‚Π΅ΠΌΠΏΠ΅Ρ€Π°Ρ‚ΡƒΡ€Ρ‹ Π²ΠΎΠ·Π΄ΡƒΡ…Π° ΠΏΠΎ-Ρ€Π°Π·Π½ΠΎΠΌΡƒ Π΄Π΅ΠΉΡΡ‚Π²ΡƒΡŽΡ‚ Π½Π° яйца Π³Π΅Π»ΡŒΠΌΠΈΠ½Ρ‚ΠΎΠ². ΠŸΡ€ΠΈ ΠΎΡ‚Ρ€ΠΈΡ†Π°Ρ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… Ρ‚Π΅ΠΌΠΏΠ΅Ρ€Π°Ρ‚ΡƒΡ€Π°Ρ… ΠΏΡ€ΠΈΠΎΡΡ‚Π°Π½Π°Π²Π»ΠΈΠ²Π°ΡŽΡ‚ΡΡ ΠΎΠ±ΠΌΠ΅Π½Π½Ρ‹Π΅ процСссы ΠΈ Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠ΅ яиц P. equorum . НаиболСС часто для уничтоТСния яиц Π³Π΅Π»ΡŒΠΌΠΈΠ½Ρ‚ΠΎΠ² ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΡƒΡŽΡ‚ ΠΊΠΎΠ½Ρ†Π΅Π½Ρ‚Ρ€ΠΈΡ€ΠΎΠ²Π°Π½Π½ΡƒΡŽ ΡΠ΅Ρ€Π½ΡƒΡŽ кислоту, ΡΠΎΠ»ΡΠ½ΡƒΡŽ, Π°Π·ΠΎΡ‚Π½ΡƒΡŽ, ΠΊΠ°Ρ€Π±ΠΎΠ»ΠΎΠ²ΡƒΡŽ кислоты, ΠΊΡ€Π΅ΠΎΠ»ΠΈΠ½, Ρ…Π»ΠΎΡ€Π½ΡƒΡŽ ΠΈΠ·Π²Π΅ΡΡ‚ΡŒ, дихлорэтан, ΠΊΡ€Π΅Π·ΠΎΠ» ΠΈ Ρ‚. Π΄. Для 100%-Π½ΠΎΠ³ΠΎ ингибирования развития яиц аскарид ΠΌΠΎΠΆΠ½ΠΎ ΠΏΡ€ΠΈΠΌΠ΅Π½ΡΡ‚ΡŒ 3 ΠΈ 5%-Π½Ρ‹Π΅ растворы Π΄Π΅Π·ΠΈΠ½Ρ„ΠΈΡ†ΠΈΡ€ΡƒΡŽΡ‰ΠΈΡ… ΠΏΡ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΎΠ² Β«Π‘ΠΈΠΎΡ€-Н», Β«Π’Π΅Π»Ρ‚ΠΎΡ€Π³Π°Π½Β» ΠΈ «Амоцид». Π‘ Ρ†Π΅Π»ΡŒΡŽ уничтоТСния яиц свиной аскариды Π±Ρ‹Π» ΠΏΡ€Π΅Π΄Π»ΠΎΠΆΠ΅Π½ ΠΌΠ΅Ρ‚ΠΎΠ΄ очистки сточных Π²ΠΎΠ΄ с ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ Ρ„ΠΈΡ‚ΠΎΠΏΠ»Π°Π½ΠΊΡ‚ΠΎΠ½Π° Clorella vulgaris ΠΈ Scenedesmys obliguus . ΠžΡ‡ΠΈΡ‰Π΅Π½Π½Π°Ρ Π² Π±ΠΈΠΎΠΏΡ€ΡƒΠ΄Π°Ρ… сточная ΠΆΠΈΠ΄ΠΊΠΎΡΡ‚ΡŒ ΠΏΠΎΠ»Π½ΠΎΡΡ‚ΡŒΡŽ очищаСтся ΠΎΡ‚ яиц Π³Π΅Π»ΡŒΠΌΠΈΠ½Ρ‚ΠΎΠ². УстановлСно Π³ΡƒΠ±ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ΅ влияниС Π½Π° яйца Π³Π΅Π»ΡŒΠΌΠΈΠ½Ρ‚ΠΎΠ² ризосфСры Π±Π°Ρ€Ρ…Π°Ρ‚Ρ†Π΅Π², ΠΊΠ°Π»Π΅Π½Π΄ΡƒΠ»Ρ‹, ячмСня, проса. Π Π°Π·Π»ΠΈΡ‡Π½Ρ‹Π΅ ΠΏΡ€ΠΎΡΡ‚Π΅ΠΉΡˆΠΈΠ΅ ΠΎΡ€Π³Π°Π½ΠΈΠ·ΠΌΡ‹ Ρ‚Π°ΠΊΠΆΠ΅ ΠΎΠΊΠ°Π·Ρ‹Π²Π°ΡŽΡ‚ влияниС Π½Π° Π²Ρ‹ΠΆΠΈΠ²Π°Π΅ΠΌΠΎΡΡ‚ΡŒ яиц Π³Π΅Π»ΡŒΠΌΠΈΠ½Ρ‚ΠΎΠ². Π’Π°ΠΊ, Amoeba verrucosa способна Π·Π°Ρ…Π²Π°Ρ‚Ρ‹Π²Π°Ρ‚ΡŒ яйца аскарид ΠΈ свободныС Π»ΠΈΡ‡ΠΈΠ½ΠΊΠΈ, Π²Ρ‹ΡˆΠ΅Π΄ΡˆΠΈΠ΅ ΠΈΠ· яиц. Π₯ΠΈΡ‰Π½Ρ‹Π΅ ΠΈΠ½Ρ„ΡƒΠ·ΠΎΡ€ΠΈΠΈ Bursaria truncatula, Stylonichia mytilus ΠΈ Stentor sp. ΠΏΠΎΠ³Π»ΠΎΡ‰Π°ΡŽΡ‚ яйца аскарид, ΠΊΠΎΡ€Π°Ρ†ΠΈΠ΄ΠΈΠ΅Π² ΡˆΠΈΡ€ΠΎΠΊΠΎΠ³ΠΎ Π»Π΅Π½Ρ‚Π΅Ρ†Π° ΠΈ ΠΌΠΈΡ€Π°Ρ†ΠΈΠ΄ΠΈΠ΅Π² ΠΏΠ΅Ρ‡Π΅Π½ΠΎΡ‡Π½ΠΎΠΉ двуустки ΠΈ ΠΏΠΎΠ»Π½ΠΎΡΡ‚ΡŒΡŽ ΠΏΠ΅Ρ€Π΅Π²Π°Ρ€ΠΈΠ²Π°ΡŽΡ‚ ΠΈΡ… Π² Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ 24-72 Ρ‡. Π’ элиминации яиц Π³Π΅Π»ΡŒΠΌΠΈΠ½Ρ‚ΠΎΠ² ΠΏΡ€ΠΈΠ½ΠΈΠΌΠ°ΡŽΡ‚ участиС ΠΎΠ»ΠΈΠ³ΠΎΡ…Π΅Ρ‚Ρ‹, рСсничныС Ρ‡Π΅Ρ€Π²ΠΈ, Π²ΠΎΠ΄Π½Ρ‹Π΅ насСкомыС, Ρ€Π°ΠΊΠΎΠΎΠ±Ρ€Π°Π·Π½Ρ‹Π΅ ΠΈ моллюски
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