Optometry in multiphasic screening: Curry County

Optometry in multiphasic screening: Curry Count

Locally deforming continuation method based on a shooting method for a class of optimal control problems

This paper proposes a new continuation method for solving optimal control problems. The proposed method is based on a shooting method. In the proposed method, a cost function of an optimal control problem is locally deformed to find the solution of the problem in a stable way. This paper also analyses a relationship between the variation of the continuation parameter and the proximity of the solutions before and after a deformation in the proposed method. The obtained relation provides guidance on how to deform the continuation parameter. The effectiveness of this method is confirmed through numerical examples

Enhancer of zeste plays an important role in photoperiodic modulation of locomotor rhythm in the cricket, Gryllus bimaculatus

Introduction: Insects show daily behavioral rhythms controlled by an endogenous oscillator, the circadian clock. The rhythm synchronizes to daily light–dark cycles (LD) and changes waveform in association with seasonal change in photoperiod. Results: To explore the molecular basis of the photoperiod-dependent changes in circadian locomotor rhythm, we investigated the role of a chromatin modifier, Enhancer of zeste (Gb’E(z)), in the cricket, Gryllus bimaculatus. Under a 12 h:12 h LD (LD 12:12), Gb’E(z) was constitutively expressed in the optic lobe, the site of the biological clock; active phase (α) and rest phase (ρ) were approximately 12 h in duration, and α/ρ ratio was approximately 1.0. When transferred to LD 20:4, the α/ρ ratio decreased significantly, and the Gb’E(z) expression level was significantly reduced at 6 h and 10 h after light-on, as was reflected in the reduced level of trimethylation of histone H3 lysine 27. This change was associated with change in clock gene expression profiles. The photoperiod-dependent changes in α/ρ ratio and clock gene expression profiles were prevented by knocking down Gb’E(z) by RNAi. Conclusions: These results suggest that histone modification by Gb’E(z) is involved in photoperiodic modulation of the G. bimaculatus circadian rhythm

A Case of Abdominal Abscess in Crohn's Disease: Successful Endoscopic Demonstration of an Obscure Enteric Fistula by Dye Injection via a Percutaneous Drainage Catheter

Abdominal and pelvic abscesses occur in approximately 10–30% of Crohn's disease patients during the course of the disease; most of these abscesses have an enteric communication. For this condition, percutaneous abscess drainage (PAD) rather than emergency surgery has recently been recognized as a valuable procedure for initial treatment. However, in cases wherein the abscess is accompanied by an enteric fistula, the recurrence of abscess might be inevitable without the management of the enteric fistula. Therefore, demonstration and evaluation of the enteric fistula is essential to prevent abscess recurrence; however, this is not necessarily a simple procedure. Here, we report abdominal abscess accompanied by a rectal fistula in a patient with Crohn's disease; this condition was successfully treated by PAD. Furthermore, PAD was also useful in identifying the fistula by colonoscopy involving dye injection via the drainage catheter. To our knowledge, no previous literature has reported the use of dye injection via the drainage catheter for identifying a fistula during endoscopic examination. We present here the radiographic, sonographic, and endoscopic findings of this case

キャピラリー電気泳動法による温泉水の分析

The aim of this study was to develop a new method for determination of inorganic cations and anions in hot spring water with capillary electrophoresis and indirect UV detection. Separations were performed with fused-silica capillary (92cm (80cm to the detector) × 50μm I.D.). Sodium, magnesium, potassium, calcium, lithium and barium as cation sample, and fluoride, chloride, bromide, nitrate, sulfate and phosphate as anions were examined. Background electrolyte solution for cations was solution containing copper (II) acetate and ethylenediamine, and background electrolyte solution for anions was solution of benzoic acid, Tris, and hexadecyltrimethylammoniumhydroxide. Concentrations, pH of background electrolyte solution and capillary temperature, applied voltage, and so on were examined. Electropherograms were obtained by means of indirect UV detection at 220nm. Separation of six cations and six anions were achieved. The detection limits for cations and anions ranged from 0.12 to 1.6ppm. The relative standard deviations (RSDs) of migration times ranged from 0.10 to 1.3%, and the RSDs of peak areas ranged from 0.99 to 2.5%. This method was applied to determine these species in different samples of hot spring water at city of Kobe in Japan. This study was reported at MSB 2006 (20th International Symposium on Microscale Bioseparations)