843 research outputs found
Tableau Formulas for One-Row Macdonald Polynomials of Types and
We present explicit formulas for the Macdonald polynomials of types and
in the one-row case. In view of the combinatorial structure, we call them
"tableau formulas". For the construction of the tableau formulas, we apply some
transformation formulas for the basic hypergeometric series involving very
well-poised balanced series. We remark that the correlation
functions of the deformed algebra generators automatically give
rise to the tableau formulas when we principally specialize the coordinate
variables
Superradiance around Rotating Dilatonic Black Hole
We consider a superradiance effect around rotating dilatonic black holes. We
analyze two cases: one is an exact solution with the coupling constant
, which effective action is reduced from the 5-dimensional
Kaluza-Klein theory, and the other is a slowly rotating dilatonic black holes
with arbitrary coupling constant. We find that there exists a critical value
(), which is predicted from a superstring model, and the
superradiant emission rate with coupling larger than the critical value becomes
much higher than the Kerr-Newman case () in the maximally charged
limit. Consequently, 4-dimensional primordial black holes in higher dimensional
unified theories are either rotating but almost neutral or charged but
effectively non-rotating.Comment: 12 pages, Latex, three figures, WU-AP/43/9
てんかん原性獲得過程におけるセロトニン受容体の関与: ラット扁桃核キンドリングモデルによる研究
取得学位:博士(医学), 学位番号:医博甲第1389号,学位授与年月日:平成12年1月19日,学位授与年:200
Cancer/Testis antigens as potential predictors of biochemical recurrence of prostate cancer following radical prostatectomy
<p>Abstract</p> <p>Background</p> <p>The Cancer/Testis Antigens (CTAs) are an important group of proteins that are typically restricted to the testis in the normal adult but are aberrantly expressed in several types of cancers. As a result of their restricted expression patterns, the CTAs could serve as unique biomarkers for cancer diagnosis/prognosis. The aim of this study was to identify promising CTAs that are associated with prostate cancer (PCa) recurrence following radical prostatectomy (RP).</p> <p>Methods</p> <p>The expression of 5 CTAs was measured by quantitative multiplex real-time PCR using prostate tissue samples obtained from 72 patients with apparently clinically localized PCa with a median of two years follow-up (range, 1 to 14 years).</p> <p>Results</p> <p>The expression of CTAs namely, CEP55, NUF2, PBK and TTK were significantly higher while PAGE4 was significantly lower in patients with recurrent disease. All CTAs with the exception of TTK were significantly correlated with the prostatectomy Gleason score, but none were correlated with age, stage, or preoperative PSA levels. In univariate proportional hazards models, CEP55 (HR = 3.59, 95% CI: 1.50-8.60), p = 0.004; NUF2 (HR = 2.28, 95% CI: 1.11-4.67), p = 0.024; and PAGE4 (HR = 0.44, 95% CI: 0.21-0.93), p = 0.031 were significantly associated with the risk of PCa recurrence. However, the results were no longer significant after adjustment for prostatectomy Gleason score.</p> <p>Conclusions</p> <p>To our knowledge, this is the first study to identify CTAs as biomarkers that can differentiate patients with recurrent and non-recurrent disease following RP and underscores its potential impact on PCa prognosis and treatment.</p
- …