Donald Jongeward interview

Donald Jongeward served as Superintendent of Buildings and Grounds and Purchasing Agent at Central Washington College of Education (predecessor to Central Washington University) between 1946 and 1974. He passed away in 2000.https://digitalcommons.cwu.edu/cwura_interviews/1120/thumbnail.jp

Generative AI in Medical Laboratory Science

This assignment is part of MLS 339 Introduction to Evidence-Based Practice. Students are introduced to Generative AI concepts, including ChatGPT, and then complete a related assignment. To complete the assignment, students generate a simple essay using ChatGPT and analyze the passage generated

Modeling and analysis tools

The topics covered are presented in viewgraph form and include the following: the effect of the Mars environment on systems; the design of models and modeling tools; space environment interaction information dissemination; tools used in the development and validation of models; Space Exploration Initiative planning; and systems integration

Some effects of the anisotropy in a simple lattice gauge model at finite temperature

Monte Carlo simulations are carried out on the (3+1)-dimensional Z(2) anisotropic lattice model, and a new method to simulate extremely anisotropic lattice systems with discrete symmetries is proposed. Dependence of the temporal and spatial average plaquette, Wilson loops on the anisotropy parameter is presented.Comment: talk given by L.A.Averchenkova at LATTICE'99 (Finite Temperature and Density), Pisa, Italy, 3 pages, Latex, 3 pictures as a ps-fil

Spacecraft-plasma interaction codes: NASCAP/GEO, NASCAP/LEO, POLAR, DynaPAC, and EPSAT

Development of a computer code to simulate interactions between the surfaces of a geometrically complex spacecraft and the space plasma environment involves: (1) defining the relevant physical phenomena and formulating them in appropriate levels of approximation; (2) defining a representation for the 3-D space external to the spacecraft and a means for defining the spacecraft surface geometry and embedding it in the surrounding space; (3) packaging the code so that it is easy and practical to use, interpret, and present the results; and (4) validating the code by continual comparison with theoretical models, ground test data, and spaceflight experiments. The physical content, geometrical capabilities, and application of five S-CUBED developed spacecraft plasma interaction codes are discussed. The NASA Charging Analyzer Program/geosynchronous earth orbit (NASCAP/GEO) is used to illustrate the role of electrostatic barrier formation in daylight spacecraft charging. NASCAP/low Earth orbit (LEO) applications to the CHARGE-2 and Space Power Experiment Aboard Rockets (SPEAR)-1 rocket payloads are shown. DynaPAC application to the SPEAR-2 rocket payloads is described. Environment Power System Analysis Tool (EPSAT) is illustrated by application to Tethered Satellite System 1 (TSS-1), SPEAR-3, and Sundance. A detailed description and application of the Potentials of Large Objects in the Auroral Region (POLAR) Code are presented

The George Washington University Budgetation, A Group Thesis Prepared by the Following Members of the 1962 Class of the Navy Graduate Financial Management Program

Were the reader to search for a definition of the term BUDGETATION in any conventional reference, the odds of his success would be indeed remote. It is a term that is offered for purposes of development as a function of Imagination, and expressed by the formula: BUDGEIATION equals BUDGET plus IMAGINATIONhttp://archive.org/details/thegeorgewashing109453879

Identification and Quantification of Regional Aerosol Trends and Impact on Clouds over the North Atlantic Ocean

Aerosols and clouds contribute to atmospheric variability and Earth’s radiative balance across local, regional, and global scales. Originating from both natural and anthropogenic sources, aerosols can cause adverse health effects and can interact directly with solar radiation as well as indirectly through complex interactions with clouds. Aerosol optical depth (AOD) has been observed from satellite platforms for over 30 years. During this time, regional changes in emissions, arising from air quality policies and socioeconomic factors, have been suggested as causes for some observed AOD trends. In the United States, the Clean Air Act and amendments have produced improvements in air quality. In this work the impacts of improved air quality on the aerosol loading and aerosol direct and indirect effects over the North Atlantic Ocean are explored using satellite, ground, and model datasets on the monthly timescale during 2002 to 2012. It is established that two trends exist in the total AOD observed by MODIS over the North Atlantic. A decreasing AOD trend between −0.02 and −0.04 per decade is observed over the mid-latitude region. Using the GOCART aerosol model it is shown that this trend results from decreases in anthropogenic species. Ground based aerosol networks (AERONET and IMPROVE) support a decreasing trend in AOD and further strengthen links to anthropogenic aerosol species, particularly sulfate species. This anthropogenic decrease occurs primarily during spring and summer. During the same time period, MODIS also observes an increasing AOD trend of 0.02 per decade located in the sub-tropical region. This trend is shown to occur during summer and is the result of natural dust aerosol. Changes in the North African environment seen in the MERRA reanalysis suggest an accelerated warming over the Saharan Desert leads to changes in the African Easterly Jet, related Easterly Waves, and baroclinicity playing a role in an increase and northward shift in African dust. Both the direct and indirect impacts of the aerosol trends are investigated. Using the SBDART radiative transfer model, estimates of the shortwave direct radiative forcing are calculated. The decrease in anthropogenic AOD produces an increase of 2.0 ± 0.3 W/m2 per decade in the Earth-system absorbance over the mid-latitude site (37.5ºN, −68.5ºE). The increase in natural AOD results in a decrease of −1.1 ± 0.2 W/m2 per decade in the Earth-system absorbance over the sub-tropical site (23.5ºN, −55.5ºE). Evaluation of the first indirect effect demonstrates agreement with Twomey theory when considering the North Atlantic domain on the whole. A regional analysis reveals the existence of counter-Twomey behavior along the U.S. Atlantic coast. Using a daily dataset during summertime with focus on warm, non-precipitating clouds, it is found that aerosol-cloud interaction in this coastal region is sensitive to vertical velocity and aerosol size. Cases experiencing updrafts (ω < 0 Pa/s) and cases of mainly coarse-mode aerosol demonstrate good agreement with Twomey theory. Additionally, cases with low specific humidity near the cloud base show non-Twomey behavior for clouds with low liquid water path

An Activating Mutation in sos-1 Identifies Its Dbl Domain as a Critical Inhibitor of the Epidermal Growth Factor Receptor Pathway during Caenorhabditis elegans Vulval Development

Proper regulation of receptor tyrosine kinase (RTK)-Ras-mitogen-activated protein kinase (MAPK) signaling pathways is critical for normal development and the prevention of cancer. SOS is a dual-function guanine nucleotide exchange factor (GEF) that catalyzes exchange on Ras and Rac. Although the physiologic role of SOS and its CDC25 domain in RTK-mediated Ras activation is well established, the in vivo function of its Dbl Rac GEF domain is less clear. We have identified a novel gain-of-function missense mutation in the Dbl domain of Caenorhabditis elegans SOS-1 that promotes epidermal growth factor receptor (EGFR) signaling in vivo. Our data indicate that a major developmental function of the Dbl domain is to inhibit EGF-dependent MAPK activation. The amount of inhibition conferred by the Dbl domain is equal to that of established trans-acting inhibitors of the EGFR pathway, including c-Cbl and RasGAP, and more than that of MAPK phosphatase. In conjunction with molecular modeling, our data suggest that the C. elegans mutation, as well as an equivalent mutation in human SOS1, activates the MAPK pathway by disrupting an autoinhibitory function of the Dbl domain on Ras activation. Our work suggests that functionally similar point mutations in humans could directly contribute to disease

Auroral interactions with ISSA

Due to its high inclination orbit, International Space Station Alpha (ISSA) will occasionally experience surface charging by the high energy electrons of the auroral environment. This study looks at the frequency of these occurrences and recapitulates a charging model. ISSA should expect about 80 auoral encounters annually. If the plasma contactor is not run continuously, the vehicle may charge several hundred volts. Charge storage on standard space station coatings should not be a problem, but care must be taken that materials are not introduced inadvertently that cannot bleed off accumulated charge in a reasonable time. A conductivity requirement may be used to ensure surface materials do not charge to high voltages, or store charge for long periods of time

The environment power system analysis tool development program

The Environment Power System Analysis Tool (EPSAT) is being developed to provide space power system design engineers with an analysis tool for determining system performance of power systems in both naturally occurring and self-induced environments. The program is producing an easy to use computer aided engineering (CAE) tool general enough to provide a vehicle for technology transfer from space scientists and engineers to power system design engineers. The results of the project after two years of a three year development program are given. The EPSAT approach separates the CAE tool into three distinct functional units: a modern user interface to present information, a data dictionary interpreter to coordinate analysis; and a data base for storing system designs and results of analysis