Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Praying Grounds: African American Faith Communities

More than a century after the publication of The Souls of Black Folk...the church remains at the center of African American social life. However, like other aspects of social history, much of the history of religious institutions is “disappearing beneath our feet,” because not enough is being done to collect and preserve the primary evidence of the work of the church and to make this archival information available to established and budding 21st-century scholars. Praying Grounds: African American Faith Communities promises to help address this problem through the collection and preservation of archival material related to the history of these institutions in Greater Cleveland... — Dr. Regennia N. Williamshttps://engagedscholarship.csuohio.edu/cmpex/1020/thumbnail.jp

Praying Grounds: African American Faith Communities

More than a century after the publication of The Souls of Black Folk...the church remains at the center of African American social life. However, like other aspects of social history, much of the history of religious institutions is “disappearing beneath our feet,” because not enough is being done to collect and preserve the primary evidence of the work of the church and to make this archival information available to established and budding 21st-century scholars. Praying Grounds: African American Faith Communities promises to help address this problem through the collection and preservation of archival material related to the history of these institutions in Greater Cleveland... — Dr. Regennia N. Williamshttps://engagedscholarship.csuohio.edu/cmpex/1020/thumbnail.jp