The Metaphysics of Mind and the Practical Science of the Law

In “Mind of a Moral Agent,” Susanna Blumenthal elegantly limns the rise and partial fall of the common sense theory of moral responsibility in American law. As Blumenthal convincingly describes it, the problem for early American jurists was nothing less than to solve the paradox of determinism and free will. How can the law declare someone morally culpable unless we are free to choose our own ends? After the Revolution, according to Blumenthal’s account, American doctors and jurists turned to a sunny, Scottish Enlightenment theory of moral responsibility. In place of the tortured moral gymnastics of an older generation of Calvinist-influenced thinkers, men like Benjamin Rush and James Wilson adopted the Scots’ idea of an innate moral faculty — a moral sensibility with which to distinguish right from wrong. The dilemma of responsibility seemed to have been solved. Human beings possessed the equipment with which to determine their fate, and if a person chose to pursue a morally wrong path, legal liability was her just desert

Moment tensor inversions of icequakes on Gornergletscher, Switzerland

We have determined seismic source mechanisms for shallow and intermediate-depth icequake clusters recorded on the glacier Gornergletscher, Switzerland, during the summers of 2004 and 2006. The selected seismic events are part of a large data set of over 80,000 seismic events acquired with a dense seismic network deployed in order to study the yearly rapid drainage of Gornersee lake, a nearby ice-marginal lake. Using simple frequency and distance scaling and Green’s functions for a homogeneous half-space, we calculated moment tensor solutions for icequakes with M_w-1.5 using a full-waveform inversion method usually applied to moderate seismic events (M_w>4) recorded at local to regional distances (≈50–700 km). Inversions from typical shallow events are shown to represent tensile crack openings. This explains well the dominating Rayleigh waves and compressive first motions observed at all recording seismograms. As these characteristics can be observed in most icequake signals, we believe that the vast majority of icequakes recorded in the 2 yr is due to tensile faulting, most likely caused by surface crevasse openings. We also identified a shallow cluster with somewhat atypical waveforms in that they show less dominant Rayleigh waves and quadrantal radiation patterns of first motions. Their moment tensors are dominated by a large double-couple component, which is strong evidence for shear faulting. Although less than a dozen such icequakes have been identified, this is a substantial result as it shows that shear faulting in glacier ice is generally possible even in the absence of extreme flow changes such as during glacier surges. A third source of icequakes was located at 100 m depth. These sources can be represented by tensile crack openings. Because of the high-hydrostatic pressure within the ice at these depths, these events are most likely related to the presence of water lenses that reduce the effective stress to allow for tensile faulting

Effect of Brief Biofeedback via a Smartphone App on Stress Recovery: Randomized Experimental Study.

BACKGROUND:Smartphones are often vilified for negatively influencing well-being and contributing to stress. However, these devices may, in fact, be useful in times of stress and, in particular, aid in stress recovery. Mobile apps that deliver evidence-based techniques for stress reduction, such as heart rate variability biofeedback (HRVB) training, hold promise as convenient, accessible, and effective stress-reducing tools. Numerous mobile health apps that may potentially aid in stress recovery are available, but very few have demonstrated that they can influence health-related physiological stress parameters (eg, salivary biomarkers of stress). The ability to recover swiftly from stress and reduce physiological arousal is particularly important for long-term health, and thus, it is imperative that evidence is provided to demonstrate the effectiveness of stress-reducing mobile health apps in this context. OBJECTIVE:The purpose of this research was to investigate the physiological and psychological effects of using a smartphone app for HRVB training following a stressful experience. The efficacy of the gamified Breather component of the Happify mobile health app was examined in an experimental setting. METHODS:In this study, participants (N=140) underwent a laboratory stressor and were randomly assigned to recover in one of three ways: with no phone present, with a phone present, with the HRBV game. Those in the no phone condition had no access to their phone. Those in the phone present condition had their phone but did not use it. Those in the HRVB game condition used the serious game Breather on the Happify app. Stress recovery was assessed via repeated measures of salivary alpha amylase, cortisol, and self-reported acute stress (on a 1-100 scale). RESULTS:Participants in the HRVB game condition had significantly lower levels of salivary alpha amylase during recovery than participants in the other conditions (F2,133=3.78, P=.03). There were no significant differences among the conditions during recovery for salivary cortisol levels or self-reported stress. CONCLUSIONS:These results show that engaging in a brief HRVB training session on a smartphone reduces levels of salivary alpha amylase following a stressful experience, providing preliminary evidence for the effectiveness of Breather in improving physiological stress recovery. Given the known ties between stress recovery and future well-being, this study provides a possible mechanism by which gamified biofeedback apps may lead to better health

Mock Modular Mathieu Moonshine Modules

We construct super vertex operator algebras which lead to modules for moonshine relations connecting the four smaller sporadic simple Mathieu groups with distinguished mock modular forms. Starting with an orbifold of a free fermion theory, any subgroup of Co_0 that fixes a 3-dimensional subspace of its unique non-trivial 24-dimensional representation commutes with a certain N=4 superconformal algebra. Similarly, any subgroup of Co_0 that fixes a 2-dimensional subspace of the 24-dimensional representation commutes with a certain N=2 superconformal algebra. Through the decomposition of the corresponding twined partition functions into characters of the N=4 (resp. N=2) superconformal algebra, we arrive at mock modular forms which coincide with the graded characters of an infinite-dimensional Z-graded module for the corresponding group. The Mathieu groups are singled out amongst various other possibilities by the moonshine property: requiring the corresponding weak Jacobi forms to have certain asymptotic behaviour near cusps. Our constructions constitute the first examples of explicitly realized modules underlying moonshine phenomena relating mock modular forms to sporadic simple groups. Modules for other groups, including the sporadic groups of McLaughlin and Higman--Sims, are also discussed.Comment: 94 pages, including 56 pages of tables; v2: updated references and minor revisions to abstract, introduction and sections 8 and

Future destinations and social inclusion scoping review:how people cured of hepatitis C (HCV) using direct- acting antiviral drugs progress in a new HCV-free world

BACKGROUND: There has been a paradigm shift in the treatment of Hepatitis C (HCV) from the interferon-era to direct-acting antiviral (DAA) drugs. Cure of HCV for the key risk group, those with a history of injecting drug use, may provide a range of benefits to an individual’s quality of life that can be additional to that of a clinical cure. The interferon-era provided evidence that cure of HCV can be a turning point for those who use drugs, supporting a recovery journey. There remains a question if DAAs can provide the same opportunity. METHODS: We employed a scoping review methodology to consider the additional non-clinical benefits that HCV cure may provide. We used the theoretical construct of recovery capital to consider how these benefits may support a recovery journey in the DAA-era. RESULTS: Our search provided 2095 articles, from which 35 were included in the analysis. We developed a thematic synthesis of the non-clinical outcomes identified based on the four over-arching themes of recovery capital: physical, cultural, social and human capital. Our review suggests that identity change is a constituent part of each of the recovery capital domains in relation to HCV treatment. CONCLUSION: We identified Social Identity Model Of Recovery (SIMOR) as a mechanism through which DAAs may provide non-clinical outcomes to increase recovery capital domains. Further research is required to develop an understanding of the impact a cure of HCV with DAAs may have on identity, overall health and wellbeing and social inclusion to support recovery journeys. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13011-022-00475-1

Identifying the Hidden Population:Former Intravenous Drug Users who are no Longer in Contact with Services. “Ask a Friend”

People who, after a period of drug use, have changed their lifestyle and left substance use behind them are a hidden population within our communities. Lack of contact with drug services may mean that they are not tested for hepatitis C (HCV) infection through service-led initiatives and, therefore, may be exposed to the chronic morbidity and risk of death inherent with a legacy of HCV infection. This study utilized respondent-driven sampling (RDS) in a novel fashion to find those at historical risk of HCV. The social networks of people with a history of drug use were mapped, and individuals not currently in contact with services were invited to come forward for testing by members of their social network. The study used a reference group to inform study methodology and communication methods to reach out to this hidden population. One hundred and nine individuals received dry blood spot tests for HCV, 17.4% were antibody positive. Fifty one individuals met the inclusion criteria for this study. One hundred and twenty three invite-to-test coupons were issued; however, only one wave of recruitment consisting of one participant resulted from this method. Using RDS in historical social networks was not effective in this study and did not reach this hidden population and increase testing for HCV. This study is registered with clinicaltrials.gov (Ref NCT03697135)

Attractive Strings and Five-Branes, Skew-Holomorphic Jacobi Forms and Moonshine

We show that certain BPS counting functions for both fundamental strings and strings arising from fivebranes wrapping divisors in Calabi--Yau threefolds naturally give rise to skew-holomorphic Jacobi forms at rational and attractor points in the moduli space of string compactifications. For M5-branes wrapping divisors these are forms of weight negative one, and in the case of multiple M5-branes skew-holomorphic mock Jacobi forms arise. We further find that in simple examples these forms are related to skew-holomorphic (mock) Jacobi forms of weight two that play starring roles in moonshine. We discuss examples involving M5-branes on the complex projective plane, del Pezzo surfaces of degree one, and half-K3 surfaces. For del Pezzo surfaces of degree one and certain half-K3 surfaces we find a corresponding graded (virtual) module for the degree twelve Mathieu group. This suggests a more extensive relationship between Mathieu groups and complex surfaces, and a broader role for M5-branes in the theory of Jacobi forms and moonshine.Comment: 36 pages, LaTeX; minor typos corrected, footnote added at bottom of page 9 to accommodate JHEP editor's suggestio