23 research outputs found

    Study of the influence of the resonance changer on the longitudinal vibration of marine propulsion shafting system

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    For investigating the characteristics of the resonance changer and its influence on the longitudinal vibration of marine propulsion shafting system, by the transfer matrix method, the model of the shafting system, including the resonance changer is established. The influences of the resonance changer with various designing parameters on the force transmissibility through the thrust bearing foundation are evaluated. The results show that, the introduction of the resonance changer eliminates the resonance at original 1st natural frequency and introduces another two resonance peaks, as well as significantly lowering the maximum response compared with the original peak. The right one is attributed to the resonance changer, while the other is due to excitation of the other shafting system components. The 2nd natural frequency moves towards the high frequency direction and the peak value nearly stay invariable. If the designing parameters of the resonance changer are well optimized, the objective of reducing the longitudinal vibration transmission through the shafting system to the hull could be achieved

    Association between Tumor necrosis factor-alpha gene polymorphisms and prostate cancer risk: a meta-analysis

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    BACKGROUND: Tumor necrosis factor-alpha (TNF-α) is an important inflammatory cytokine that may play a role in controlling the progression of prostate cancer. Two common polymorphisms in the TNF-α gene, −308G/A and −238C/T, have been suggested to alter the risk for prostate cancer, but the results have been inconclusive so far. In order to obtain a better understanding of the effects of these two polymorphisms on prostate cancer risk, all available studies were considered in a meta-analysis. METHODS: We conducted a comprehensive literature search in the Cochrane Library, PubMed, EMBASE, Chinese Biomedical Literature database (CBM), and the China National Knowledge Infrastructure (CNKI). The associations were evaluated by calculating the pooled odds ratio (OR) with 95% confidence interval (95% CI). RESULTS: In this meta-analysis, we included 14 studies with 5,757 patients and 6,137 control subjects for the TNF-α-308G/A polymorphism and 1,967 patients and 2,004 control subjects for the TNF-α-238C/T polymorphism. A significantly increased prostate cancer risk was found to be associated with the TNF-α-308C/T polymorphism in studies with healthy volunteers (AA + AG vs. GG: OR = 1.531, 95% CI = 1.093–2.145; P = 0.013; AG vs. GG: OR = 1.477, 95% CI = 1.047–2.085; P = 0.026). No significant association was found between the TNF-α-238G/A polymorphism and prostate cancer risk in the overall or subgroup analyses. There was no risk of publication bias in this meta-analysis. CONCLUSIONS: Our results suggest that while the TNF-α-238G/A polymorphism may not be associated with prostate cancer the TNF-α-308C/T polymorphism may significantly contribute to prostate cancer susceptibility in healthy volunteers. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/162928812011630

    Case-based power transformer diagnose model using nonlinear mapping of oil chromatography

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    In this study, a case-based diagnostic model of a power transformer for oil chromatography is proposed. A nonlinear normalised mapping method is proposed for achieving ideal distribution characteristics of oil chromatogram gas in the case base. A similarity degree algorithm is proposed to calculate the similarity degree in the target spatial domain between the case to be diagnosed and the cases in the case base. A threshold method is proposed to determine the number of similar cases. Also, a method for calculating the weight of the diagnosis result according to the case distribution in the case base is proposed. The diagnostic method proposed is used to deploy the diagnostic system on the Internet. Defeat diagnosis conclusions of two transformers by the method and system in this paper are consistent with the disintegration results. It can be concluded that the proposed method has important practical application value in engineering

    Metal–Organic Frameworks with Phosphotungstate Incorporated for Hydrolytic Cleavage of a DNA-Model Phosphodiester

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    Five phosphotungstate-incorporated metal–organic frameworks {[Eu<sub>4</sub>(dpdo)<sub>9</sub>(H<sub>2</sub>O)<sub>16</sub>PW<sub>12</sub>O<sub>40</sub>]}­(PW<sub>12</sub>O<sub>40</sub>)<sub>2</sub>·(dpdo)<sub>3</sub>·Cl<sub>3</sub> (<b>1</b>); {ZnNa<sub>2</sub>(μ-OH)­(dpdo)<sub>4</sub>(H<sub>2</sub>O)<sub>4</sub>[PW<sub>12</sub>O<sub>40</sub>]}·3H<sub>2</sub>O (<b>2</b>); {Zn<sub>3</sub>(dpdo)<sub>7</sub>}­[PW<sub>12</sub>O<sub>40</sub>]<sub>2</sub>·3H<sub>2</sub>O (3); and [Ln<sub>2</sub>H­(μ-O)<sub>2</sub>(dpdo)<sub>4</sub>(H<sub>2</sub>O)<sub>2</sub>]­[PW<sub>12</sub>O<sub>40</sub>]·3H<sub>2</sub>O (Ln = Ho for <b>4</b> and Yb for <b>5</b>) (dpdo = 4,4′-bipyridine-<i>N</i>,<i>N</i>′-dioxide) have been synthesized through a one-step hydrothermal reaction and characterized by elemental analyses, infrared (IR) spectroscopy, photoluminescence, and single-crystal X-ray diffraction (XRD). The structural analyses indicate that <b>1</b>–<b>5</b> display diversity structure from one-dimensional (1D) to three-dimensional (3D) series of hybrids. Kinetic experiments for the hydrolytic cleavage of DNA-model phosphodiester BNPP (bis­(<i>p</i>-nitrophenyl)­phosphate) were followed spectrophotometrically for the absorbance increase at 400 nm in EPPS (4-(2-hydroxyethyl)­piperazine-1-propane sulfonic acid) buffer solution, because of the formation of <i>p</i>-nitrophenoxide with <b>1</b>–<b>5</b> under conditions of pH 4.0 and 50 °C. Ultraviolet (UV) spectroscopy indicate that the cleavage of the phosphodiester bond proceeds with the pseudo-first-order rate constant in the range of 10<sup>–7</sup>–10<sup>–6</sup> s<sup>–1</sup>, giving an inorganic phosphate and <i>p</i>-nitrophenol as the final products of hydrolysis. The results demonstrate that <b>1</b>–<b>5</b> have good catalytic activity and reusability for hydrolytic cleavage of BNPP

    Metal–Organic Frameworks with Phosphotungstate Incorporated for Hydrolytic Cleavage of a DNA-Model Phosphodiester

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    Five phosphotungstate-incorporated metal–organic frameworks {[Eu<sub>4</sub>(dpdo)<sub>9</sub>(H<sub>2</sub>O)<sub>16</sub>PW<sub>12</sub>O<sub>40</sub>]}­(PW<sub>12</sub>O<sub>40</sub>)<sub>2</sub>·(dpdo)<sub>3</sub>·Cl<sub>3</sub> (<b>1</b>); {ZnNa<sub>2</sub>(μ-OH)­(dpdo)<sub>4</sub>(H<sub>2</sub>O)<sub>4</sub>[PW<sub>12</sub>O<sub>40</sub>]}·3H<sub>2</sub>O (<b>2</b>); {Zn<sub>3</sub>(dpdo)<sub>7</sub>}­[PW<sub>12</sub>O<sub>40</sub>]<sub>2</sub>·3H<sub>2</sub>O (3); and [Ln<sub>2</sub>H­(μ-O)<sub>2</sub>(dpdo)<sub>4</sub>(H<sub>2</sub>O)<sub>2</sub>]­[PW<sub>12</sub>O<sub>40</sub>]·3H<sub>2</sub>O (Ln = Ho for <b>4</b> and Yb for <b>5</b>) (dpdo = 4,4′-bipyridine-<i>N</i>,<i>N</i>′-dioxide) have been synthesized through a one-step hydrothermal reaction and characterized by elemental analyses, infrared (IR) spectroscopy, photoluminescence, and single-crystal X-ray diffraction (XRD). The structural analyses indicate that <b>1</b>–<b>5</b> display diversity structure from one-dimensional (1D) to three-dimensional (3D) series of hybrids. Kinetic experiments for the hydrolytic cleavage of DNA-model phosphodiester BNPP (bis­(<i>p</i>-nitrophenyl)­phosphate) were followed spectrophotometrically for the absorbance increase at 400 nm in EPPS (4-(2-hydroxyethyl)­piperazine-1-propane sulfonic acid) buffer solution, because of the formation of <i>p</i>-nitrophenoxide with <b>1</b>–<b>5</b> under conditions of pH 4.0 and 50 °C. Ultraviolet (UV) spectroscopy indicate that the cleavage of the phosphodiester bond proceeds with the pseudo-first-order rate constant in the range of 10<sup>–7</sup>–10<sup>–6</sup> s<sup>–1</sup>, giving an inorganic phosphate and <i>p</i>-nitrophenol as the final products of hydrolysis. The results demonstrate that <b>1</b>–<b>5</b> have good catalytic activity and reusability for hydrolytic cleavage of BNPP

    Metal–Organic Frameworks with Phosphotungstate Incorporated for Hydrolytic Cleavage of a DNA-Model Phosphodiester

    No full text
    Five phosphotungstate-incorporated metal–organic frameworks {[Eu<sub>4</sub>(dpdo)<sub>9</sub>(H<sub>2</sub>O)<sub>16</sub>PW<sub>12</sub>O<sub>40</sub>]}­(PW<sub>12</sub>O<sub>40</sub>)<sub>2</sub>·(dpdo)<sub>3</sub>·Cl<sub>3</sub> (<b>1</b>); {ZnNa<sub>2</sub>(μ-OH)­(dpdo)<sub>4</sub>(H<sub>2</sub>O)<sub>4</sub>[PW<sub>12</sub>O<sub>40</sub>]}·3H<sub>2</sub>O (<b>2</b>); {Zn<sub>3</sub>(dpdo)<sub>7</sub>}­[PW<sub>12</sub>O<sub>40</sub>]<sub>2</sub>·3H<sub>2</sub>O (3); and [Ln<sub>2</sub>H­(μ-O)<sub>2</sub>(dpdo)<sub>4</sub>(H<sub>2</sub>O)<sub>2</sub>]­[PW<sub>12</sub>O<sub>40</sub>]·3H<sub>2</sub>O (Ln = Ho for <b>4</b> and Yb for <b>5</b>) (dpdo = 4,4′-bipyridine-<i>N</i>,<i>N</i>′-dioxide) have been synthesized through a one-step hydrothermal reaction and characterized by elemental analyses, infrared (IR) spectroscopy, photoluminescence, and single-crystal X-ray diffraction (XRD). The structural analyses indicate that <b>1</b>–<b>5</b> display diversity structure from one-dimensional (1D) to three-dimensional (3D) series of hybrids. Kinetic experiments for the hydrolytic cleavage of DNA-model phosphodiester BNPP (bis­(<i>p</i>-nitrophenyl)­phosphate) were followed spectrophotometrically for the absorbance increase at 400 nm in EPPS (4-(2-hydroxyethyl)­piperazine-1-propane sulfonic acid) buffer solution, because of the formation of <i>p</i>-nitrophenoxide with <b>1</b>–<b>5</b> under conditions of pH 4.0 and 50 °C. Ultraviolet (UV) spectroscopy indicate that the cleavage of the phosphodiester bond proceeds with the pseudo-first-order rate constant in the range of 10<sup>–7</sup>–10<sup>–6</sup> s<sup>–1</sup>, giving an inorganic phosphate and <i>p</i>-nitrophenol as the final products of hydrolysis. The results demonstrate that <b>1</b>–<b>5</b> have good catalytic activity and reusability for hydrolytic cleavage of BNPP

    REVIEW Open Access Association between Tumor necrosis factor-alpha

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    gene polymorphisms and prostate cancer risk: a meta-analysi

    Face-selective tungstate ions drive zinc oxide nanowire growth direction and dopant incorporation

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    Controlling the growth processes of nanowires is vital for tailoring their properties. Here, the presence of tungstate ions on specific surface planes of zinc oxide nanowires causes nanowire growth and chemical doping along specific crystal planes
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