248 research outputs found

    The Performance of a Diesel Engine Fueled with Diesel Oil, Biodiesel and Preheated Coconut Oil

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    Fossil fuel crisis and depletion, environmental pollution and ever-increase in vehicle and transportation means have renewed the scientist\u27s interest in the world in order to look for potential alternative fuels, which are attractive such as biodiesel, bioethanol, DME and vegetable oils. Inedible vegetable oils such as coconut oil, Jatropha oil, linseed oil or animal fat are full of potential for using directly or manufacturing biodiesel. This work is carried out in order to study the four stroke diesel engine D240 performance characteristics fueled with preheated pure coconut oil (PCO), Jatropha oil methyl ester (JOME) and compare with diesel oil (DO). The test diesel engine performance such as power (Ne), torque (Me), specific fuel consumption (ge) and thermal efficiency (ηe) is determined, calculated and evaluated while using JOME, preheated PCO and compared to DO. The results show that, power (Ne), torque (Me) and thermal efficiency (ηe) while engine is fueled with JOME and PCO are lower, otherwise specific fuel consumption (ge) is higher than those of diesel fuel, the test engine performance are gained the best for JOME and PCO100. Keywords: biofuel, biodiesel, preheated vegetable oils, engine performance, efficiency, specific fuel consumption.Article History: Received Dec 9, 2016; Received in revised form January 28, 2017; Accepted February 4, 2017; Available onlineHow to Cite This Article: Hoang, T.A and Le,V. V. (2017). The Performance of A Diesel Engine Fueled With Diesel Oil, Biodiesel and Preheated Coconut Oil. International Journal of Renewable Energy Development, 6(1), 1-7.http://dx.doi.org/10.14710/ijred.6.1.1-

    Forest plot of MTT on LBP, TNF-α, IL-6 and NO.

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    Forest plot of MTT on LBP, TNF-α, IL-6 and NO.</p

    PRISMA 2009 checklist.

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    (DOC)</p

    Forest plot of MTT on HVPG reduction in cirrhosis patients.

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    Forest plot of MTT on HVPG reduction in cirrhosis patients.</p

    Forest plot according to duration of MTT on HVPG reduction in cirrhosis patients.

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    Forest plot according to duration of MTT on HVPG reduction in cirrhosis patients.</p

    The characteristics of the included studies.

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    The characteristics of the included studies.</p

    Chemical Synthesis of the Repeating Unit of Type V Group B <i>Streptococcus</i> Capsular Polysaccharide

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    The first chemical synthesis of the heptasaccharide repeating unit of type V group B <i>Streptococcus</i> capsular polysaccharide (CPS) by a preactivation-based one-pot [2 + 1 + 4] glycosylation strategy is described. The synthetic efficiency was further improved by using diol glycosyl acceptors for regio-/stereoselective glycosylation reactions. The synthetic target contains a free amino group at the reducing end, facilitating additional regioselective elaboration. The results should be useful for synthetic and biological studies of related CPSs

    Effects of Flanking Loops on Membrane Insertion of Transmembrane Helices: A Role for Peptide Conformational Equilibrium

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    The ability of a transmembrane helix (TMH) to insert into a lipid bilayer has been mainly understood based on the total hydrophobicity of the peptide sequence. Recently, Hedin et al. investigated the influence of flanking loops on membrane insertion of a set of marginally hydrophobic TMHs using translocon-based membrane integration assays. While the flanking loops were found to facilitate the insertion in most cases, counter examples also emerged where the flanking loops hinder membrane insertion and contradict the hydrophobicity and charge distribution analyses. Here, coarse-grained free energy calculations and atomistic simulations were performed to investigate the energetics and conformational details of the membrane insertion of two representative marginally hydrophobic TMHs with (NhaL and EmrL) and without (NhaA and EmrD) the flanking loops. The simulations fail to directly recapitulate the contrasting effects of the flanking loops for these two TMHs, due to systematic overprediction of the stabilities of the transmembrane states that has also been consistently observed in previous studies. Nonetheless, detailed force decomposition and peptide conformation analyses suggest a novel mechanism on how the peptide conformational equilibrium in the aqueous phase may modulate the effects of flanking loops on membrane insertion. Specifically, the flanking loops in peptide EmrL interact strongly with the TMH segment and form stable compact conformations in the aqueous phase, which can hinder membrane absorption and insertion as these processes require extended conformations with minimal interactions between the flanking loops and TMH segment. This work also emphasizes the general importance of considering the peptide conformational equilibrium for understanding the mechanism and energetics of membrane insertion, an aspect that has not yet been sufficiently addressed in the literature

    Synthesis of a Tristearoyl Lipomannan via Preactivation-Based Iterative One-Pot Glycosylation

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    A convergent and efficient strategy was developed for the synthesis of lipomannan (LM), useful for vaccine development. Thioglycosides were employed as glycosyl donors to construct two key pseudotrisaccharide and tetramannose intermediates through preactivation-based glycosylation strategy. These building blocks were then successfully coupled to form the LM core, which was lapidated, phospholipidated, and finally globally deprotected to afford the target molecule. The intermediate LM core involved in this synthesis contained orthogonal protections, which would facilitate its variable modifications for the preparation of other complex LM derivatives and for the synthesis of LM conjugates as LM-based vaccines
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