What I believe about leadership and education : reflective research

In the field of education, having a great leader is very important. The principal is like a captain of a ship. He can lead that ship right down the middle so that his students and staff can see things from both sides or he can run aground and really cause some problems. Leadership is something that must come from within. You can definitely tell when you are around someone that is a natural leader and someone who is trying their hardest. A leader is someone who is well read on the new and innovative changes in education. They are caring, organized, always ready to listen, good communicators, visible in the community as well as the hallways, and they are in this profession for the students that they are working with

Magnetized black holes and black rings in the higher dimensional dilaton gravity

In this paper we consider magnetized black holes and black rings in the higher dimensional dilaton gravity. Our study is based on exact solutions generated by applying a Harrison transformation to known asymptotically flat black hole and black ring solutions in higher dimensional spacetimes. The explicit solutions include the magnetized version of the higher dimensional Schwarzschild-Tangherlini black holes, Myers-Perry black holes and five dimensional (dipole) black rings. The basic physical quantities of the magnetized objects are calculated. We also discuss some properties of the solutions and their thermodynamics. The ultrarelativistic limits of the magnetized solutions are briefly discussed and an explicit example is given for the $D$-dimensional magnetized Schwarzschild-Tangherlini black holes.Comment: LaTeX, 23 pages; v2 references and comments added, some typos corrected;v3 minor change

Who Are Today’s Farmers and What are Their Educational Needs?

Labor and Human Capital, Teaching/Communication/Extension/Profession,

Effects of a supplement designed to increase ATP levels on muscle strength, power output, and endurance

<p>Abstract</p> <p>Background</p> <p>The present study examined the acute effects of a nutritional supplement intended to improve adenosine triphosphate (ATP) concentrations on vertical jump height, isometric strength of the leg extensors, leg extension endurance, and forearm flexion endurance.</p> <p>Methods</p> <p>Twenty-four healthy men (mean age ± SD = 23 ± 4 yrs, stature = 181 ± 7 cm, and body mass = 82 ± 12 kg) volunteered to complete a familiarization trial plus 2 randomly-ordered experimental trials separated by a 7-day washout period. Participants received either 6 (body mass < 91 kg) or 8 (body mass ≥ 91 kg) tablets of the treatment (TR; 625 mg of adenylpyrophosphoric acid and calcium pyruvate, 350.8 mg of cordyceps sinensis extract and yohimbine hydrochloride) or placebo (PL; 980 mg of microcrystalline cellulose) 1 hour prior to the following tests: countermovement vertical jump (CVJ), forearm flexion repetitions to exhaustion, isometric maximal voluntary contractions (MVCs) of the leg extensors, and a 50-repetition maximal concentric isokinetic leg extension endurance test.</p> <p>Results</p> <p>There were no differences between the TR and PL trials for CVJ height (<it>P </it>> 0.05), isometric MVC peak torque (<it>P </it>> 0.05), maximal concentric isokinetic peak torque (<it>P </it>> 0.05), percent decline during the leg extension endurance tests (<it>P </it>> 0.05), or repetitions to exhaustion during the forearm flexion endurance tests (<it>P </it>> 0.05).</p> <p>Conclusion</p> <p>These findings indicated no improvements in the measured variables as a result of ingesting this nutritional supplement. Future studies should examine whether chronic supplementation or a loading period is necessary to observe any ergogenic effects of this supplement.</p

Analysis of Expression Patterns: The Scope of the Problem, the Problem of Scope

Studies of the expression patterns of many genes simultaneously lead to the observation that even in closely related pathologies, there are numerous genes that are differentially expressed in consistent patterns correlated to each sample type. The early uses of the enabling technology, microarrays, was focused on gathering mechanistic biological insights. The early findings now pose another clear challenge, finding ways to effectively use this kind of information to develop diagnostics

Mapping of the gene encoding the [alpha]-subunit of the human H+, K+-ATPase to chromosome 19q13.1 by fluorescent in Situ hybridization

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/29823/1/0000169.pd

Evidence for linear extrachromosomal elements mediating gene amplification in the multidrug-resistant J774.2 murine cell line

Previous studies from our laboratory have demonstrated specific cytogenetic alterations accompanying development of colchicine resistance in the J774.2 murine cell line and in two sublines (J7.Cl-30 and J7.Cl-100) [1]. Although gene amplification is not observed in the parental J774.2 cell line, a ~35-fold amplification of the gene for p-glycoprotein (mdr) was noted in the J7.Cl-30 subline (770-fold CLCR) and a ~70-fold amplification in the J7.Cl-100 subline (2500-fold CLCR). In this study, we analyzed the localization and organization of the mdr gene. In the colchicine-resistant (CLCR) J7.Cl-30 subline, the p-glycoprotein domain was observed to reside on differently sized extrachromosomal elements. Our results indicate not only circular extrachromosomal elements but also linear extrachromosomal elements. By means of pulsed-field gel electrophoresis (PFGE), the sizes of the extrachromosomal elements were shown to be &gt;2,500 kilobasepairs (kb), 800 kb, and 400 kb. In contrast, the J7.Cl-100 subline was characterized by the presence of homogeneously staining regions (HSRs). We have noted that with increasing colchicine resistance the extrachromosomal elements are replaced by HSRs. Our findings of linear elements that appear to be precursors of HSRs may offer a new way to interpret different theories of extrachromosomal gene amplification. The J7.Cl-30 cell line presents a unique system to analyze further the formation and structure of extrachromosomal elements.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/30158/1/0000541.pd

GeneLink: a database to facilitate genetic studies of complex traits

BACKGROUND: In contrast to gene-mapping studies of simple Mendelian disorders, genetic analyses of complex traits are far more challenging, and high quality data management systems are often critical to the success of these projects. To minimize the difficulties inherent in complex trait studies, we have developed GeneLink, a Web-accessible, password-protected Sybase database. RESULTS: GeneLink is a powerful tool for complex trait mapping, enabling genotypic data to be easily merged with pedigree and extensive phenotypic data. Specifically designed to facilitate large-scale (multi-center) genetic linkage or association studies, GeneLink securely and efficiently handles large amounts of data and provides additional features to facilitate data analysis by existing software packages and quality control. These include the ability to download chromosome-specific data files containing marker data in map order in various formats appropriate for downstream analyses (e.g., GAS and LINKAGE). Furthermore, an unlimited number of phenotypes (either qualitative or quantitative) can be stored and analyzed. Finally, GeneLink generates several quality assurance reports, including genotyping success rates of specified DNA samples or success and heterozygosity rates for specified markers. CONCLUSIONS: GeneLink has already proven an invaluable tool for complex trait mapping studies and is discussed primarily in the context of our large, multi-center study of hereditary prostate cancer (HPC). GeneLink is freely available at