Koncentracija Сa,P i Mg u krvnom serumu jagnjadi hranjenih smešama sa različitim dodatkom preparata na bazi prirodnog zeolita

This work has an aim to explore the effects of the product based on the natural zeolit during the fattening of the lambs and also the effects on contents of calcium, phosphorus and magnesium in blood serum. The experiment lasted 15 days in the closed area of the Agricultural school in Kraljevo, and the lambs were divided into three groups of 15 lambs ( Control group –C, Experimental group E1 and E2). They were fed with sheep’s milk, concentrate for lambs’ fattening and meadow hay. The lambs in the experimental groups, in contrast to Control group, were fed with the different concentration of the preparation based on the natural zeolit (O1=1%, O2=1.5%), so that the manifested differences would be treated as the resault of the different concentration of the zeolit that was added to the lambs’ food.At the end of the experiment the differences in the parameters of the lambs’ blood serum were distinguished and especially in the concentration of calcium, phosphorus and magnesium.Istraživanja u ovom radu postavljena su sa ciljem da se ispitaju efekti korišćenja preparata na bazi prirodnog zeolita u ishrani jagnjadi u tovu kao i utvrđivanje efekata na sadržaj kalcijuma, fosfora i magnezijuma u krvnom serumu. Ogled je izveden u trajanju od 90 dana, u zatvorenom objektu Poljoprivredne škole u Kraljevu, a eksperimentalne životinje su podeljene u tri grupe po 15. jagnjadi (Kontrolna-K i Ogledne-O1 i O2). Obrok se sastojao od ovčjeg mleka, koncentrata za tov jagnjadi i livadskog sena. Jagnjad oglednih grupa, za razliku od kontrolne, dobijala su različite koncentracije preparata na bazi prorodnog zeolita (O1=1%, O2=1.5%), kako bi se na taj način ispoljene razlike tretirale kao posledica sadržaja različite količine dodatog zeolita u hrani. Na kraju ogleda su utvrđene razlike u ispitivanim parametrima iz krvnog seruma jagnjadi i to u koncentraciji kalcijuma , fosfora i magnezijuma

THE AMOUNT OF SOME MINERAL SUBSTANCES IN COWS ’ BLOOD SERUM FED WITH CORN SILAGE**

Abstract: The amount of calcium, phosphorus and magnesium in milking cows ’ blood was tested and it is one of indicators that cows were fed with these substances. The average amount of calcium in tested cows ’ blood is 11.58mg/100ml serum, the average amount of phosphorus is 5,14mg/100ml and the average amount of magnesium is 3,03/100mg. Key words: cow, calcium, phosphorus and magnesium

A preliminary evaluation of leukocyte phospho-glucocorticoid receptor as a potential biomarker of depressogenic vulnerability in healthy adults

The mechanism of maladaptive chronic stress response involves altered phosphorylation of the glucocorticoid receptor (GR). In this study, we investigated if important depressogenic vulnerability factors, such as neuroticism and self-reports of negative affective states, may be associated with alterations in levels of the GR and GR phosphoisoforms in peripheral blood mononuclear cells (PBMC) of healthy adults. In 21 women and 16 men we evaluated PMBC levels of total GR (tGR), GR phosphorylated at serine 211 (pGR-S211) and serine 226 (pGR-S226) and correlated these data with personality traits and current reports of stress, anxiety and depression. Also, we assessed plasma cortisol levels in all tested subjects. Our results showed that in women nuclear pGR-S226 was positively correlated with neuroticism and current reports of depression, anxiety and stress, while the ratio of nuclear pGR-S211/pGR-S226 was negatively correlated with reports of depression. None of the aforementioned correlations were significant in men. No significant relations between cortisol levels and any of GR parameters were observed. These preliminary findings highlight the value of GR phosphorylation-related research in identifying molecular biomarkers of depressogenic vulnerability, at least in women. (C) 2013 Elsevier Ireland Ltd. All rights reserved

Fetal sex and the circulating renin-angiotensin system during early gestation in women who later develop preeclampsia or gestational hypertension

There are fetal sex-specific differences in the balance between angiotensin (Ang) II and Ang-(1–7) in the maternal circulation during pregnancy. To determine whether at 15 weeks’ gestation plasma levels of Ang II and Ang-(1–7), as well as levels of prorenin and Ang-converting enzyme (ACE), predicted the development of gestational hypertension (GH) or preeclampsia (PreE) and were associated with estimates of fetal and maternal health, women who later developed GH (n=50) or PreE (n=50) were compared with body mass index-matched controls (n=100). Women who subsequently developed PreE or GH had increased Ang-(1–7) levels at 15 weeks’ gestation compared with women with normal pregnancies. When separated by fetal sex, this difference was seen only in women carrying a female fetus. Prorenin and ACE concentrations were not useful biomarkers for the prediction of either PreE or GH at 15 weeks’ gestation. Women with a male fetus who developed PreE and women who subsequently developed GH had increased blood pressures at 15 weeks’ gestation compared with women with normal pregnancies, suggesting that these women were on an early trajectory for the development of hypertension. We propose that measurement of Ang-(1–7) during early gestation could be useful in predicting, those women who will go on to develop new-onset hypertension in pregnancy.SD Sykes, KG Pringle, A Zhou, GA Dekker, CT Roberts and ER Lumber