Changing the conversation: Artists\u27 books, zines and broadsides from the Collins Memorial Library Collection

An exhibition catalog for the Collins Memorial Library exhibit, Changing the Conversation. Edited by Jane Carlin with essays by Carletta Carrington Wilson, MalPina Chan, Katy Curtis, Amy E. Ryken, Marshall Weber, Alisa Banks, Jane Carlin, and Sha Towers

Anton Zwemmer: London\u27s Bookseller and Publisher for the Arts

Anton Zwemmer was a Dutch bookseller and publisher who settled in England during the early 1900s, fostering the growth and development of specialized art book selling and publishing

Libraries And Institutional Research

The article explores best practices for establishing collaborations between small liberal arts university libraries and institutional research (IR) professionals. Topics discussed include national surveys commonly used by IR institutions in examining students\u27 attitudes, relevance of the surveys on university libraries and benefits that IR collaborations can bring to libraries. Also described is the collaborative effort between the library and IR departments of the University of Puget Sound

René Lalique: Enchanted by Glass

Review of René Lalique: Enchanted by Glass, Reviewed May 2015 by Jane Carlin, Library Director, Collins Memorial Library, University of Puget Sound, [email protected]

The Art Book Tradition in Twentieth-Century Europe

Review of The Art Book Tradition in Twentieth-Century Europe, Reviewed May 2014 by Jane A. Carlin, Library Director, Collins Memorial Library, University of Puget Sound, [email protected]

Extend Your Experience: The Northwest\u27s Natural and Cultural Landscape

The article provides information on the natural and cultural landscape of the Pacific Northwest, the venue for the Association of the College and Research Libraries (ACRL) 14th National Conference in Seattle, Washington on March 12-15, 2009. It discusses various tourist attractions found within the area, as well as its climate. A recount of various historical events that happened in the place, as well as the culture of the living inhabitants is also presented. Computer information resources of several sceneries found within the area of Washington state is presented

Corrigendum: Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis

B cells are implicated in rheumatoid arthritis (RA) based on the presence of autoantibodies and the therapeutic response to B cell depletion. IL-21 has a significant role in B cell development and function. Here we assess B cell responses to IL-21 and the mechanisms responsible for altered IL-21R expression in RA. Flow cytometry of PBMC and cultured B cells was used to quantify protein and mRNA levels of IL-21R, IL-21 signaling through pSTAT3, specificity protein 1 (SP1) and to determine cytokine production (IL-6) and maturation status of B cells in RA and healthy control subjects. SP1 binding to the IL21R promoter region in B cells was assessed with ChIP-qPCR. We demonstrate an increase in IL-21R expression in total and memory B cells from RA subjects, which correlated with responsiveness to IL-21 stimulation. Stimulation of naïve RA B cells with IL-21 and CD40L resulted in an increase in differentiation into plasmablasts and an increase in IL-6 production in comparison to healthy controls, which was dose dependent on IL-21 stimulation. IL-21R expression on memory B cells in RA synovial fluid was comparable to peripheral blood making our study pertinent to understanding B cell responses in the joint and site of inflammation. We identified an increase in SP1 protein and mRNA in RA B cells and demonstrate an increase in binding of SP1 to the IL21R promoter region, which suggests a mechanism by which IL-21R expression is enhanced on B cells in RA. Taken together, our results indicate a mechanism by which IL-21 enhances B cell development and function in RA through an SP1 mediated increase in IL-21R expression on B cells

Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis

B cells are implicated in rheumatoid arthritis (RA) based on the presence of autoantibodies and the therapeutic response to B cell depletion. IL-21 has a significant role in B cell development and function. Here we assess B cell responses to IL-21 and the mechanisms responsible for altered IL-21R expression in RA. Flow cytometry of PBMC and cultured B cells was used to quantify protein and mRNA levels of IL-21R, IL-21 signaling through pSTAT3, specificity protein 1 (SP1) and to determine cytokine production (IL-6) and maturation status of B cells in RA and healthy control subjects. SP1 binding to the IL21R promoter region in B cells was assessed with ChIP-qPCR. We demonstrate an increase in IL-21R expression in total and memory B cells from RA subjects, which correlated with responsiveness to IL-21 stimulation. Stimulation of naïve RA B cells with IL-21 and CD40L resulted in an increase in differentiation into plasmablasts and an increase in IL-6 production in comparison to healthy controls, which was dose dependent on IL-21 stimulation. IL-21R expression on memory B cells in RA synovial fluid was comparable to peripheral blood making our study pertinent to understanding B cell responses in the joint and site of inflammation. We identified an increase in SP1 protein and mRNA in RA B cells and demonstrate an increase in binding of SP1 to the IL21R promoter region, which suggests a mechanism by which IL-21R expression is enhanced on B cells in RA. Taken together, our results indicate a mechanism by which IL-21 enhances B cell development and function in RA through an SP1 mediated increase in IL-21R expression on B cells

Information Competencies for Students in Design Disciplines

Information Competencies for Students in Design Disciplines, for the first time, compiles a list of core information literacy skills for students. Divided into basic, intermediate, and advanced skills in each design discipline, this set of competencies is an invaluable aid to librarians as they strive to define and delimit information literacy skills for students in design disciplines. These competencies are intended to facilitate a systematic means of integrating information literacy skills into the core curriculum of design students, as well as to open lines of communication with faculty as to how competencies can be integrated into specific course goals. The authors developed Information Competencies for Students in Design Disciplines with previously established information literacy standards at its foundation. The ACRL Information Literacy Competency Standards for Higher Education as well as specific standards in other disciplines such as Information Literacy Standards for Science and Engineering/Technology were consulted in the creation of these standards