10,406 research outputs found

    ENDOGENOUS QUALITY AND AGRICULTURAL POLICY ANALYSIS

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    The typical analysis of agricultural policy assumes that the commodity of interest is homogeneous, and that it does not change as a result of policy implementation. This paper develops a model of agricultural policy analysis when the restriction of product homogeneity is relaxed and policy-induced quality responses are incorporated.agricultural policy analysis, quality variation, Agricultural and Food Policy,

    Bargaining rationale for cooperative generic advertising

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    The beggar-thy-neighbour aspect of commodity advertising means that benefits to one commodity from advertising come at the expense of other commodities. The effect can be mitigated by cooperation among groups as shown by Alston, Freebairn and James (AFJ). A drawback to AFJ’s analysis is that some cooperative outcomes require side payments from one producer group to another. This paper offers a bargaining solution as an alternative to cooperation in the case where cooperative side payments would be needed. We show that while bargaining without side payments is not as effective as cooperation at reducing beggar-thy-neighbour effects, it is a welfare improving alternative to non-cooperation and is likely more practical in many situations.Marketing,

    Taxes and quality: A market-level analysis

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    Aconventional assumption of product homogeneity when the commodity of interest is actually heterogeneous will lead to errors in an analysis of the incidence of policies, such as taxes. In this article, an equilibrium displacement model is used to derive analytical solutions for price, quantity, and quality effects of ad valorem and per unit taxes. The results show how parameters determine the effects of tax policies on quality. The potential for tax-induced distortions in quality, and the distributive consequences of those distortions, are illustrated in a case study of the market for Australian wine.Resource /Energy Economics and Policy,

    Levy-funded research choices by producers and society

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    Commodity levies are used increasingly to fund producer collective goods such as research and promotion. In the present paper we examine theoretical relationships between producer and national benefits from levy‐funded research, and consider the implications for the appropriate rates of matching government grants, applied with a view to achieving a closer match between producer and national interests. In many cases the producer and national optima coincide. First, regardless of the form of the supply shift, when product demand is perfectly elastic, or all the product is exported, domestic benefits and costs of levy‐funded research all go to producers and they have appropriate incentives. Second, if research causes a parallel supply shift, the producer share of research benefits is the same as their share of costs of a levy, and their incentives are compatible with national interests. In such cases, a matching grant would cause an over‐investment in research from a national perspective. However, if demand is less than perfectly elastic, and research causes a pivotal supply shift, the producer share of benefits is smaller than their share of costs of the levy, and they will under‐invest in research from a national point of view. A matching grant can be justified in such cases, however the magnitude of the optimal grant is sensitive to market conditions.Research and Development/Tech Change/Emerging Technologies,

    Surgical Management of Massive Labial Edema in a Gravid Preeclamptic Diabetic

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    Background. Massive labial edema is a rare complication during pregnancy that can jeopardize vaginal delivery, as well as leading to maternal and fetal morbidity. It can be related to systemic pathologies, but has been commonly associated with preeclampsia and diabetes. This increased and sometimes longstanding pressure may result in a “labial compartment syndrome� leading to microvascular damage and tissue necrosis if not resolved in a timely fashion. Case. Massive labial edema was treated first conservatively and then surgically in a gravid diabetic patient with severe preeclampsia. Immediately after Cesarean section, the labial compartment syndrome was relieved surgically and resolved rapidly. Conclusion. When conservative attempts at management of labial edema fail, or rapid resolution is critical to maternal and fetal outcome, surgical alternatives should be considered

    Simplifying Satellite and Ground Data Validation with Level-2 Subsetting

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    We demonstrate that scientists can simplify their satellite data validation workflow with the use of NASA Godddard Earth Sciences Data and Information Services Center (GES DISC) subsetting services. We perform a sample validation of Aura ozone products collocated with ground-based ozone measurements using subsetting services to trim satellite data to only the relevant user-defined variables and spatio-temporal region. Because the subsetting service automatically returns only relevant data granules that adhere to a set of user-defined coincidence criteria, user workload is greatly reduced. Moreover, the resultant data files are substantially smaller than full data granules due to the subsetting service further culling the data to the relevant geospatio-temporal coincidence criteria, user-defined variables, and user-defined dimensions of variables. This decreases data download throughput and file storage requirements. The validation presented here quantifies the time and file size savings that can be achieved by utilizing subsetting services within the satellite data validation workflow

    A Human Torque Teno Virus Encodes a MicroRNA That Inhibits Interferon Signaling

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    Rodney P. Kincaid, James M. Burke, Jennifer C. Cox, Christopher S. Sullivan, The University of Texas at Austin, Molecular Genetics and Microbiology, Austin, Texas, United States of AmericaEthel-Michele de Villiers, Division for the Characterization of Tumorviruses, Deutsches Krebsforschungszentrum, Heidelberg, GermanyTorque teno viruses (TTVs) are a group of viruses with small, circular DNA genomes. Members of this family are thought to ubiquitously infect humans, although causal disease associations are currently lacking. At present, there is no understanding of how infection with this diverse group of viruses is so prevalent. Using a combined computational and synthetic approach, we predict and identify miRNA-coding regions in diverse human TTVs and provide evidence for TTV miRNA production in vivo. The TTV miRNAs are transcribed by RNA polymerase II, processed by Drosha and Dicer, and are active in RISC. A TTV mutant defective for miRNA production replicates as well as wild type virus genome; demonstrating that the TTV miRNA is dispensable for genome replication in a cell culture model. We demonstrate that a recombinant TTV genome is capable of expressing an exogenous miRNA, indicating the potential utility of TTV as a small RNA vector. Gene expression profiling of host cells identifies N-myc (and STAT) interactor (NMI) as a target of a TTV miRNA. NMI transcripts are directly regulated through a binding site in the 3′UTR. SiRNA knockdown of NMI contributes to a decreased response to interferon signaling. Consistent with this, we show that a TTV miRNA mediates a decreased response to IFN and increased cellular proliferation in the presence of IFN. Thus, we add Annelloviridae to the growing list of virus families that encode miRNAs, and suggest that miRNA-mediated immune evasion can contribute to the pervasiveness associated with some of these viruses.This work was supported by grants RO1AI077746 from the National Institutes of Health, RP110098 from the Cancer Prevention and Research Institute of Texas, a Burroughs Wellcome Investigators in Pathogenesis Award to CSS, a UT Austin Powers Graduate Fellowship to RPK, a UT Austin Institute for Cellular and Molecular Biology fellowship, and the DKFZ for EMdV. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Molecular BiosciencesMicrobiologyEmail: [email protected]

    Consumer Purchases of Biotech Sweet Corn: Results from a Market Experiment

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    In the increasingly consumer-driven food system, consumer preferences toward agricultural biotechnology have the potential to influence decisions about development and adoption of biotech crop varieties. Current knowledge about consumer attitudes toward biotech foods is largely based on a number of consumer surveys and a growing body of experimental auctions. This paper reports results of a market experiment designed to isolate the effect of the use of biotechnology on consumer choices between two otherwise identical products. Two related varieties of fresh-market sweet corn were grown, labeled, and sold side-by-side in nine participating grocery stores in the Philadelphia area. Sales data indicate a market share of biotech corn of about 45 percent, with store-specific shares varying between 10 and 80 percent. Over 700 surveys were collected in stores. Surprisingly, only 65 percent of respondents noticed that there were two types of corn for sale despite the labeling and merchandising, and 87 percent of the sample spent one minute or less choosing their corn. About half of the respondents had heard of biotechnology before, and 16 percent volunteered the biotechnology trait as an influence on their purchase decision. Approximately 40 percent of the sample purchased some of the biotech variety, with several respondents purchasing some of each.Institutional and Behavioral Economics,

    BacillOndex: An Integrated Data Resource for Systems and Synthetic Biology

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    BacillOndex is an extension of the Ondex data integration system, providing a semantically annotated, integrated knowledge base for the model Gram-positive bacterium Bacillus subtilis. This application allows a user to mine a variety of B. subtilis data sources, and analyse the resulting integrated dataset, which contains data about genes, gene products and their interactions. The data can be analysed either manually, by browsing using Ondex, or computationally via a Web services interface. We describe the process of creating a BacillOndex instance, and describe the use of the system for the analysis of single nucleotide polymorphisms in B. subtilis Marburg. The Marburg strain is the progenitor of the widely-used laboratory strain B. subtilis 168. We identified 27 SNPs with predictable phenotypic effects, including genetic traits for known phenotypes. We conclude that BacillOndex is a valuable tool for the systems-level investigation of, and hypothesis generation about, this important biotechnology workhorse. Such understanding contributes to our ability to construct synthetic genetic circuits in this organism
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