40 research outputs found
Clarifying leadership roles in ERP implementation projects
Existence of an adequate project champion role has been identified as a critical success factor in Enterprise Resource Planning (ERP) implementation projects. However, the figure of the project champion is not yet quite well understood. Some authors relate it with the project sponsor figure while others relate it with the project manager figure. This paper tries to clarify these concepts. Our research framework is based upon an extensive ERP literature review and a web survey. The findings of this web survey suggest that the adequate project champion role is that of the project sponsor, emerging as a dual-role champion.ERP, Leadership , Roles
A goals/questions/metrics plan for monitoring user involvement and participation in ERP (...)
ERP implementation success is influenced by a large number of factors. User involvement and participation is one of the most cited critical success factors in ERP implementation projects, and one of the most critical ones for their satisfactory outcome. This study attempts to define a set of metrics for monitoring user involvement and participation within ERP implementation projects by using the Goals/Questions/Metrics method. First, a literature review is presented. Second, a framework for monitoring user involvement and participation in ERP implementation projects is proposed. And third, a Goals/Questions/Metrics preliminary plan is proposed to monitor and control user involvement.ERP, Involvement, Participation, Metrics, Goals, Questions
Análisis del desarrollo del gobierno electrónico municipal en España
Este estudio se centra en el área de gobierno electrónico a nivel municipal. La investigación realizada ha tenido por objetivo la identificación del nivel de desarrollo de los servicios de gobierno electrónico en el entorno municipal en España. Los resultados muestran que la mayorÃa de las ciudades españolas no tienen un crecimiento sostenible y por fases en el ámbito de estrategia de Gobierno Electrónico. El estudio resalta la necesidad de una estrategia a largo plazo en la implantación del Gobierno Electrónico municipal de forma que se cree una arquitectura digital sostenible.
An Updated ERP Systems Annotated Bibliography: 2001-2005
This study provides an updated annotated bibliography of ERP publications published in the main IS conferences and journals during the period 2001-2005, categorizing them through an ERP lifecycle-based framework that is structured in phases. The first version of this bibliography was published in 2001 (Esteves and Pastor, 2001c). However, so far, we have extended the bibliography with a significant number of new publications in all the categories used in this paper. We also reviewed the categories and some incongruities were eliminated.ERP
Implementing and improving the SEI risk management method in a university software project
Although risk management approaches appeared more than one decade ago, there is the evidence of low penetration rate of their techniques in software projects. One of the most known methods is the SEI Software Continuous Risk Management (SEI-CRM) method. This paper addresses the usage of the SEI-CRM method in a big software development project. The study we carried out suggests that SEI-CRM is limited in terms of the organizational risk perspective. This research is expected to contribute with the knowledge on risk management for software development projects by for which we propose to extend the SEI-CRM method with some organizational risk factors that we have found relevant from our study.Risk, Risk management, SEI-CRM , Organizational risks
The Impact of Individual and Social Attitude in Business Information Technology Knowledge Sharing
This exploratory study attempts to analyze the way women and men perceive talking about information and communication technology, and its impact in knowledge sharing. Based in 14 focus groups we have defined a conceptual model to interpret this impact in ICT knowledge sharing. Our research findings show that there are differences between men and women, thus gender is a critical factor in ICT knowledge sharing. Also, social, cultural and educational factors have a strong negative impact in their behaviour. Furthermore, we posit that the attitude predisposes a favourable (men) and unfavourable (women) reaction to talk about ICT and this affects ICT knowledge sharing.Focus group, Gender, Knowledge
Understanding the ERP Project Champion Role and Its Criticality
Existence of an adequate project champion role has been identified as a critical success factor in ERP implementation projects. However, the figure of the project champion is not yet quite well understood. Some authors relate it with the project sponsor figure while others relate it with the project manager figure. This paper tries to clarify these concepts. Our research framework has been based upon an extensive ERP literature review and a web survey. The findings of this survey show that the adequate project champion role is that of the project sponsor; respondents also think that both project manager and project sponsor are critical to the success of an ERP implementation project and not merely the project champion figure. We also show the interdependence between project sponsor role, project manager role and ERP project success, for which we present an interdependence model
Generation and characterization of monoclonal antibodies against Rift Valley fever virus nucleoprotein
Due to the unpredictable and explosive nature of Rift Valley fever (RVF) outbreaks,
rapid and accurate diagnostic assays for low-resource settings are urgently
needed. To improve existing diagnostic assays, monoclonal antibodies (MAbs)
specific for the nucleocapsid protein of RVF virus (RVFV) were produced and
characterized. Four IgG2a MAbs showed specific binding to denatured nucleocapsid
protein, both from a recombinant source and from inactivated RVFV, in
Western blot analysis and in an enzyme-linked immunosorbent assay (ELISA).
Cross-reactivity with genetically related and non-related arboviruses including
Bunyamwera and Calovo viruses (Bunyaviridae family), West Nile and Dengue-2
viruses (Flaviviridae family), and Sindbis and Chikungunya viruses (Togaviridae
family) was not detected. These MAbs represent a useful tool for the development
of rapid diagnostic assays for early recognition of RVF.SIDA/SAREC –Eduardo Mondlane University; the Utrecht University, The Netherlands and Southern African Centre for Infectious
Disease Surveillance (SACIDS).http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1865-1682hb2014ab201
The germline mutational landscape of BRCA1 and BRCA2 in Brazil
The detection of germline mutations in BRCA1 and BRCA2 is essential to the formulation of clinical management strategies, and in Brazil, there is limited access to these services, mainly due to the costs/availability of genetic testing. Aiming at the identification of recurrent mutations that could be included in a low-cost mutation panel, used as a first screening approach, we compiled the testing reports of 649 probands with pathogenic/likely pathogenic variants referred to 28 public and private health care centers distributed across 11 Brazilian States. Overall, 126 and 103 distinct mutations were identified in BRCA1 and BRCA2, respectively. Twenty-six novel variants were reported from both genes, and BRCA2 showed higher mutational heterogeneity. Some recurrent mutations were reported exclusively in certain geographic regions, suggesting a founder effect. Our findings confirm that there is significant molecular heterogeneity in these genes among Brazilian carriers, while also suggesting that this heterogeneity precludes the use of screening protocols that include recurrent mutation testing only. This is the first study to show that profiles of recurrent mutations may be unique to different Brazilian regions. These data should be explored in larger regional cohorts to determine if screening with a panel of recurrent mutations would be effective.This work was supported in part by grants from Barretos Cancer Hospital (FINEP - CT-INFRA, 02/2010), Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP, 2013/24633-2 and 2103/23277-8), Fundação de Apoio à Pesquisa do Rio Grande do Norte (FAPERN), Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ), Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (FAPERGS), Ministério da Saúde, the Breast Cancer Research Foundation (Avon grant #02-2013-044) and National Institute of Health/National Cancer Institute (grant #RC4 CA153828-01) for the Clinical Cancer Genomics Community Research Network. Support in part was provided by grants from Fundo de Incentivo a Pesquisa e Eventos (FIPE) from Hospital de Clínicas de Porto Alegre, by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES, BioComputacional 3381/2013, Rede de Pesquisa em Genômica Populacional Humana), Secretaria da Saúde do Estado da Bahia (SESAB), Laboratório de Imunologia e Biologia Molecular (UFBA), INCT pra Controle do Câncer and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq). RMR and PAP are recipients of CNPq Productivity Grants, and Bárbara Alemar received a grant from the same agencyinfo:eu-repo/semantics/publishedVersio
The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2
Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age 6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score 652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701