The study of parameter optimization in vehicle-borne tracking systems Final technical report

Data smoothing technique for parameter optimization in free flight orbit vehicle-borne tracking system

A mathematical model of tumor self-seeding reveals secondary metastatic deposits as drivers of primary tumor growth

Two models of circulating tumor cell (CTC) dynamics have been proposed to explain the phenomenon of tumor 'self-seeding', whereby CTCs repopulate the primary tumor and accelerate growth: Primary Seeding, where cells from a primary tumor shed into the vasculature and return back to the primary themselves; and Secondary Seeding, where cells from the primary first metastasize in a secondary tissue and form microscopic secondary deposits, which then shed cells into the vasculature returning to the primary. These two models are difficult to distinguish experimentally, yet the differences between them is of great importance to both our understanding of the metastatic process and also for designing methods of intervention. Therefore we developed a mathematical model to test the relative likelihood of these two phenomena in the subset of tumours whose shed CTCs first encounter the lung capillary bed, and show that Secondary Seeding is several orders of magnitude more likely than Primary seeding. We suggest how this difference could affect tumour evolution, progression and therapy, and propose several possible methods of experimental validation.Comment: 20 pages, 4 figure

Multi-wavelength visibility measurements of the red giant R Doradus

We present visibility measurements of the nearby Mira-like star R Doradus taken over a wide range of wavelengths (650--990 nm). The observations were made using MAPPIT (Masked APerture-Plane Interference Telescope), an interferometer operating at the 3.9-m Anglo-Australian Telescope. We used a slit to mask the telescope aperture and prism to disperse the interference pattern in wavelength. We observed in R Dor strong decreases in visibility within the TiO absorption bands. The results are in general agreement with theory but differ in detail, suggesting that further work is needed to refine the theoretical models.Comment: 8 pages; SPIE Conf. 4006 "Interferometry in Optical Astronomy

Hyperatlas: A New Framework for Image Federation

Hyperatlas is an open standard intended to facilitate the large-scale federation of image-based data. The subject of hyperatlas is the space of sphere-to-plane projection mappings (the FITS-WCS information), and the standard consists of coherent collections of these on which data can be resampled and thereby federated with other image data. We hope for a distributed effort that will produce a multi-faceted image atlas of the sky, made by federating many different surveys at different wavelengths and different times. We expect that hyperatlas-compliant imagery will be published and discovered through an International Virtual Observatory Alliance (IVOA) registry, and that grid-based services will emerge for the required resampling and mosaicking.Comment: Published in ADASS XIII proceeding