3,693 research outputs found
Accountability of Central Banks: Aspects and Quantification
This paper starts with a discussion of the various aspects of accountability of central banks. On the basis of this discussion we construct an indicator for accountability for 16 central banks, including the European Central Bank. It is shown that the degree of accountability differs considerably and that the ECB has a rather low score. The indicator is used to examine the relationship between central bank independence and accountability. It is concluded that although there appears to be a negative relationship between independence and accountability, this does certainly not imply that a central bank cannot both be independent and accountable.central bank independence;central bank accountability;European central bank
Water scarcity and institutional change: lessons in adaptive governance from the drought experience of Perth, Western Australia
Urban water systems will be increasingly challenged under future climates and global pressures. Meeting challenges by reconfiguring water systems to integrate supplies and deliver multifunctional uses is technically well described. Adjusting the institutions that frame the management of these systems is not well operationalized in practice or conceptualized in theory. This study seeks to address this gap through an institutional analysis of Perth, Australia, a city where drought crisis has put under pressure both management practices and the institutional setting that underlies them. The study found that while trusted practices moderated water scarcity, the stability of the institutional setting may not facilitate a shift toward adaptable institutional configurations suited to future conditions. The results identified three key ingredients for a flexible institutional setting: (i) feedbacks in the system through better information management, (ii) reflexive dialogue and strategic use of projects to generate greater learning opportunities, and (iii) policy level support for sector-wide collaboration through progressive agendas, incentives for innovation and capacity building in stakeholder and community engagement. Further, the results suggest that a deeper understanding of institutional dynamics is needed to enable adaptive governance. The paper provides an analytical framework for diagnosing how greater adaptive capacity might be mobilized through influencing these dynamics
A method for mechanical generation of radio frequency fields in nuclear magnetic resonance force microscopy
We present an innovative method for magnetic resonance force microscopy
(MRFM) with ultra-low dissipation, by using the higher modes of the mechanical
detector as radio frequency (rf) source. This method allows MRFM on samples
without the need to be close to an rf source. Furthermore, since rf sources
require currents that give dissipation, our method enables nuclear magnetic
resonance experiments at ultra-low temperatures. Removing the need for an
on-chip rf source is an important step towards a MRFM which can be widely used
in condensed matter physics.Comment: 7 pages, 5 figures, to be submitted to Physical Review Applie
Correlations of record events as a test for heavy-tailed distributions
A record is an entry in a time series that is larger or smaller than all
previous entries. If the time series consists of independent, identically
distributed random variables with a superimposed linear trend, record events
are positively (negatively) correlated when the tail of the distribution is
heavier (lighter) than exponential. Here we use these correlations to detect
heavy-tailed behavior in small sets of independent random variables. The method
consists of converting random subsets of the data into time series with a
tunable linear drift and computing the resulting record correlations.Comment: Revised version, to appear in Physical Review Letter
Is there Life in the Old Dog Yet? Observations on the Political Economy and Constitutional Viability of Common Debt Issuing in the Euro Area
Departing from a political economy analysis of the benefits of common debt issuance by the Eurozone member states, we examine to what extent the various proposals for Eurobonds may be considered admissible under EU law and exemplary national (constitutional) laws, including those of Germany, Estonia, France, Ireland and Poland, from which one can deduce general national constitutional requirements applicable in all Eurozone member states. The medium and long-Term potential gain
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'
We combined large-scale mRNA expression analysis and gene mapping to identify genes and loci that control hematopoietic stem cell (HSC) function. We measured mRNA expression levels in purified HSCs isolated from a panel of densely genotyped recombinant inbred mouse strains. We mapped quantitative trait loci (QTLs) associated with variation in expression of thousands of transcripts. By comparing the physical transcript position with the location of the controlling QTL, we identified polymorphic cis-acting stem cell genes. We also identified multiple trans-acting control loci that modify expression of large numbers of genes. These groups of coregulated transcripts identify pathways that specify variation in stem cells. We illustrate this concept with the identification of candidate genes involved with HSC turnover. We compared expression QTLs in HSCs and brain from the same mice and identified both shared and tissue-specific QTLs. Our data are accessible through WebQTL, a web-based interface that allows custom genetic linkage analysis and identification of coregulated transcripts.
Functional kernel estimators of conditional extreme quantiles
We address the estimation of "extreme" conditional quantiles i.e. when their
order converges to one as the sample size increases. Conditions on the rate of
convergence of their order to one are provided to obtain asymptotically
Gaussian distributed kernel estimators. A Weissman-type estimator and kernel
estimators of the conditional tail-index are derived, permitting to estimate
extreme conditional quantiles of arbitrary order.Comment: arXiv admin note: text overlap with arXiv:1107.226
Association of cognitive performance with clinical staging in schizophrenia spectrum disorders:a prospective 6-year follow-up study
BACKGROUND: Clinical staging has been developed to capture the large heterogeneity in schizophrenia spectrum disorders. Including cognitive performance in the staging model may improve its clinical validity. Moreover, cognitive functioning could predict transition across stages. However, current evidence of the association between cognition and clinical staging is inconsistent. Therefore, we aim to assess whether cognitive parameters are associated with clinical stages in a large sample of patients with schizophrenia spectrum disorders and to identify cognitive markers at baseline that are associated with stage-transition at three and six-year follow-up. METHODS: We applied the staging model of Fusar-Poli et al. (2017) in 927 patients with non-affective psychotic disorders, assessed at baseline, and after three and six-year follow-up. Cognitive performance was assessed with a standard test battery. Generalized linear mixed models were used to analyze associations of cognitive performance with staging and stage-transition at follow-up. RESULTS: Findings showed that higher stages of illness were significantly associated with lower processing speed (F = 3.688, p = 0.025) and deficits in working memory (F = 6.365, p = 0.002) across assessments. No associations between cognitive parameters at baseline and stage-transition at three- and six-year follow-up were found. CONCLUSION: We conclude that processing speed and working memory were modestly associated with higher stages of illness in schizophrenia spectrum disorders, thereby slightly improving its clinical validity. However, associations were small and we found no evidence for predictive validity
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