Periodontal Care as a Fundamental Step for an Active and Healthy Ageing

In the industrialized part of the world, an increasing number of people live the old age without too many restrictions due to illness or physiological impairment. This group is known as the young elderly. On the contrary, a consistent part of seniors develops a greater number of medical conditions and become more and more dependent, these are the old elderly. The first cause of tooth lost in industrialized word is periodontitis that generally strikes people older than 40 years and determines serious detriment of the stomatognatic organ. Smoking and stress are risk factors for periodontitis that are common and shared between young, adult, and older age. Diabetes mellitus, obesity, and osteoporosis are very frequent pathological situations in older age. They have been identified as cofactors in the progression of periodontitis. Many dental associations recognize the importance of continued research on oral fluids diagnostics and welcome the development of rapid point-of-care tests providing accurate measurements of clinically validated biomarkers. At present, well-studied molecules associated with host response factors and with derived tissue destruction mediators have been proposed as diagnostic biomarkers for periodontitis detected in the oral fluids

Soft tissues healing at immediate transmucosal implants placed into molar extraction sites associated with buccal self-contained dehiscences. A 12-month controlled clinical trial.

Aim: To assess soft tissues healing at immediate transmucosal implants placed into molar extraction sites associated with buccal self-contained dehiscences. Study design: 12-month controlled clinical trial. Material and methods: Test subjects received immediate transmucosal implants placed in molar extraction sockets displaying a buccal bone dehiscence with a height and width of ≥ 3 mm, respectively. Peri-implant marginal defects were treated according to the principles of Guided Bone Regeneration (GBR) by means of deproteinized bovine bone mineral particles in conjunction with a bioresrobable collagen membrane. Control subjects received implants in healed molar sites with intact buccal bone walls following tooth extraction. Tapered-effect implants with an endosseous diameter of 4.8 mm and a shoulder diameter of 6.5 mm were placed in both groups. Flaps were repositioned and sutured allowing non-submerged, transmucosal soft tissues healing. Pocket probing depths (PPD) and clinical attachment levels (CAL) were compared between test and control implants at the 12-month follow-up. Results: 30 subjects (16 males and 14 females) were enrolled and followed for 12 months. They contributed with 30 tapered-effect implants. All implants healed uneventfully yielding a survival rate of 100%. At the 12-month follow-up, statistically significant higher (p<0.05) PPD and CAL values were recorded around all aspects of test implants compared with those of control implants. Conclusions: The findings of this controlled clinical trial showed that healing following immediate transmucosal implant placement in molar extraction sites with shallow and wide buccal dehiscences was inferior compared with that of control implants placed in healed bone and resulted in lack of complete osseointegration

Clinical Outcomes Following Treatment of Non-contained Intrabony Defects with Enamel Matrix Derivative (EMD) or Guided Tissue Regeneration (GTR). A 12-month Randomized Controlled Clinical trial

The purpose of this study is to compare the healing of deep, non-contained intrabony defects (i.e., with a ?80% 1-wall component and a residual 2- to 3-wall component in the most apical part) treated with either an enamel matrix derivative (EMD) or guided tissue regeneration (GTR) after 12 months

Clinical, radiographic, and esthetic evaluation of immediately loaded laser microtextured implants placed into fresh extraction sockets in the anterior maxilla: a 2-year retrospective multicentric study.

Objectives:To assess the clinical, radiographic, and esthetic outcomes of implants with a laser microtextured collar placed in the anterior region of the maxilla at the time of tooth extraction and immediately temporized.Methods:Forty-six Tapered Internal Laser-Lok BioHorizons implants were immediately placed and immediately restored with nonfunctional loading in 46 patients (24 men and 22 women) with a thick gingival biotype, ideal gingival level/contour, and postextraction intact walls. Survival rate, cortical bone loss, and periimplant mucosal responses were evaluated at 6, 12, and 24 months.Results:Survival rate was 95.6%. Mean mesial and distal marginal bone loss, 24 months after installation, were 0.58 mm (SD = 0.53; range, 0.17-1.15) and 0.57 mm (SD = 0.70; range, 0.42-1.10), respectively. A mesial and distal papilla regrowth mean of 1.8 and 1.5 mm, respectively, were found. The midfacial soft tissue levels showed 0.12 mm of mean recession after 24 months.Conclusion:Immediate implants with a laser microtextured surface restored at the day of surgery, may be considered as a predictable procedure in terms of implant survival and hard and soft tissue remodeling.OBJECTIVES: To assess the clinical, radiographic, and esthetic outcomes of implants with a laser microtextured collar placed in the anterior region of the maxilla at the time of tooth extraction and immediately temporized. METHODS: Forty-six Tapered Internal Laser-Lok BioHorizons implants were immediately placed and immediately restored with nonfunctional loading in 46 patients (24 men and 22 women) with a thick gingival biotype, ideal gingival level/contour, and postextraction intact walls. Survival rate, cortical bone loss, and periimplant mucosal responses were evaluated at 6, 12, and 24 months. RESULTS: Survival rate was 95.6%. Mean mesial and distal marginal bone loss, 24 months after installation, were 0.58 mm (SD = 0.53; range, 0.17-1.15) and 0.57 mm (SD = 0.70; range, 0.42-1.10), respectively. A mesial and distal papilla regrowth mean of 1.8 and 1.5 mm, respectively, were found. The midfacial soft tissue levels showed 0.12 mm of mean recession after 24 months. CONCLUS

Clinical and radiographic outcomes of a combined resective and regenerative approach in the treatment of peri-implantitis: a prospective case series

AIM To assess the clinical and radiographic outcomes applying a combined resective and regenerative approach in the treatment of peri-implantitis. MATERIALS AND METHODS Subjects with implants diagnosed with peri-implantitis (i.e., pocket probing depth (PPD) ≥5 mm with concomitant bleeding on probing (BoP) and ≥2 mm of marginal bone loss or exposure of ≥1 implant thread) were treated by means of a combined approach including the application of a deproteinized bovine bone mineral and a collagen membrane in the intrabony and implantoplasty in the suprabony component of the peri-implant lesion, respectively. The soft tissues were apically repositioned allowing for a non-submerged healing. Clinical and radiographic parameters were evaluated at baseline and 12 months after treatment. RESULTS Eleven subjects with 11 implants were treated and completed the 12-month follow-up. No implant was lost yielding a 100% survival rate. At baseline, the mean PPD and mean clinical attachment level (CAL) were 8.1 ± 1.8 mm and 9.7 ± 2.5 mm, respectively. After 1 year, a mean PPD of 4.0 ± 1.3 mm and a mean CAL of 6.7 ± 2.5 mm were assessed. The differences between the baseline and the follow-up examinations were statistically significant (P = 0.001). The mucosal recession increased from 1.7 ± 1.5 at baseline to 3.0 ± 1.8 mm at the 12-month follow-up (P = 0.003). The mean% of sites with BoP+ around the selected implants decreased from 19.7 ± 40.1 at baseline to 6.1 ± 24.0 after 12 months (P = 0.032). The radiographic marginal bone level decreased from 8.0 ± 3.7 mm at baseline to 5.2 ± 2.2 mm at the 12-month follow-up (P = 0.000001). The radiographic fill of the intrabony component of the defect amounted to 93.3 ± 13.0%. CONCLUSION Within the limits of this study, a combined regenerative and resective approach for the treatment of peri-implant defects yielded positive outcomes in terms of PPD reduction and radiographic defect fill after 12 months

Soft tissue stability related to mucosal recession at dental implants: a systematic review.

OBJECTIVES To assess the stability of soft tissues around implants by comparing mucosal recessions in patients with keratinized mucosa (test) with patients without keratinized mucosa (control) around osseointegrated dental implants. METHOD AND MATERIALS The PICO criteria used were as follows: Population, patients with osseointegrated dental implants; Intervention/exposure, presence of a keratinized mucosa; Comparison/control, absence of keratinized mucosa; Outcome, presence or absence of peri-implant mucosal recessions (mm). DATA SOURCES An electronic search of Medline, Embase, and Cochrane Oral Health Group specialist trials supplemented by manual searching was conducted to identify studies reporting outcomes of at least 5 years on the presence of mucosal recessions at implants with or without attached mucosa. Mucosal recession (MR) was set as primary outcome. Prospective cohort studies published in English language up to October 2018, with a mean follow-up period of at least 5 years, reporting keratinized tissue height ≥ 2 mm and < 2 mm or presence/absence of keratinized tissue, with fixed implant-supported prostheses. The homogeneity of studies was assessed by DerSimonian and Laird test (Q test). The differences in terms of gingival recession around implants reported between test groups (keratinized mucosa ≥ 2 mm) and control (keratinized mucosa < 2 mm or no keratinized mucosa) were compared. Two studies reporting 201 patients with 514 tissue level implants were selected for the final analysis. RESULTS Due to the high heterogeneity between the selected studies, no statistical test could be performed. However, in both studies a deeper mucosal recession occurred when keratinized mucosa was < 2 mm: 0.61 ± 0.10 (-0.90; -0.32) and -1.92 ± 0.12 (-2.16; -1.68), respectively. CONCLUSION Within their limitations, the findings indicate that after a mean observation period of at least 5 years, the presence of keratinized mucosa may lead to less mucosal recession at dental implants

The impact of a laser-microtextured collar on crestal bone level and clinical parameters under various placement and loading protocols

Physical attachment of connective tissue fibers to a laser-microtextured (8- and 12-\u3bcm grooves) surface on the collar of an implant has been demonstrated using human histology. Related clinical research has suggested that this microtextured surface may help to decrease initial bone loss after implant placement. The aim of this retrospective study was to compare crestal bone heights and clinical parameters between implants with laser-microtextured and machined collars placed and loaded with different protocols

The role of surgical flap design (minimally invasive flap vs. extended flap with papilla preservation) on the healing of intrabony defects treated with an enamel matrix derivative: a 12-month two-center randomized controlled clinical trial.

OBJECTIVES Minimally invasive flap designs have been introduced to enhance blood clot stability and support wound healing. Limited data appear to suggest, that in intrabony defects, better clinical outcomes can be achieved by means of minimally invasive flap compared to more extended flaps. The aim of this study was to evaluate the healing of intrabony defects treated with either minimally invasive surgical flaps or with modified or simplified papilla preservation techniques in conjunction with the application of an enamel matrix derivative (EMD). MATERIALS AND METHODS Forty-seven subjects were randomly assigned to either test (N = 23) or control (N = 24) procedures. In the test group, the intrabony defects were accessed by means of either minimally invasive surgical technique (MIST) or modified minimally invasive surgical technique (M-MIST) according to the defect localization while the defects in the control group were treated with either the modified or simplified papilla preservation (MPP) or the simplified papilla preservation technique (SPP). EMD was used as regenerative material in all defects. The following clinical parameters were recorded at baseline and after 12 months: full-mouth plaque score (FMPS), full-mouth bleeding score (FMBS), probing depths (PD), clinical attachment level (CAL), and gingival recession (GR). Early healing index (EHI) score was assessed in both groups 1 week following the surgery. CAL gain was set as primary outcome. RESULTS After 12 months follow-up, the CAL gain was 4.09 ± 1.68 mm in test group and 3.79 ± 1.67 mm in control group, while the PD reduction was 4.52 ± 1.34 mm and 4.04 ± 1.62 mm for test and control sites. In both groups, a minimal GR increase (0.35 ± 1.11 mm and 0.25 ± 1.03 mm) was noted. No residual PDs ≥ 6 mm were recorded in both groups. CAL gains of 4-5 mm were achieved in 30.4% and in 29.2% of test and control group, respectively. Moreover, CAL gains ≥ 6 mm were recorded in 21.7% of experimental sites and in 20.8% of control sites. No statistically significant differences in any of the evaluated parameters were found between the test and control procedures (P > 0.05). After 1 week post-surgery, a statistically significant difference (P < 0.05) between the groups was found in terms of EHI score. CONCLUSIONS Within the limits of this pilot RCT, the results have failed to show any differences in the measured parameters following treatment of intrabony defects with EMD, irrespective of the employed surgical technique. CLINICAL RELEVANCE In intrabony defects, the application of EMD in conjunction with either MIST/M-MIST or M-PPT/SPPT resulted in substantial clinical improvements