6,282 research outputs found
Plasmon dispersion in quasi-one and one-dimensional systems with non-magnetic impurities
We calculate the plasmon dispersion in quasi-one-dimensional quantum wires,
in the presence of non-magnetic impurities, taking into consideration the
memory function formalism and the role of the forward scattering. The plasma
frequency is reduced by the presence of impurities. We also calculate,
analytically, the plasmon dispersion in the Born approximation, for the
scattering of the electrons by the non-magnetic impurities. We compare our
result with the numerical results of Sarma and Hwang.Comment: 12 pages, no figures, Physica E, 40, 474, (2008
In vivo investigation of the tissue response to commercial Teflon insulin infusion sets in large swine for 14 days: the effect of angle of insertion on tissue histology and insulin spread within the subcutaneous tissue.
Objective: This study investigated the effects of the inflammatory tissue response (ITR) to an insulin infusion set (IIS) on insulin bolus spread over wear time, as well as the effect of cannula insertion angle on the ITR, bolus shape, and pump tubing pressure.
Research design and methods: Angled or straight IISs were inserted every other day for 14 days into the subcutaneous tissue of 11 swine and insulin was delivered continuously. Prior to euthanasia, a 70 µL bolus of insulin/X-ray contrast agent was infused while recording a pressure profile (peak tubing pressure, pmax; area under the pressure curve, AUC), followed by the excision of the tissue-catheter specimen. Bolus surface area (SA) and volume (V) were assessed via micro-CT. Tissue was stained to analyze total area of inflammation (TAI) and inflammatory layer thickness (ILT) surrounding the cannula.
Results: A bolus delivered through an angled IIS had a larger mean SA than a bolus delivered through a straight cannula (314.0±84.2 mm2 vs 229.0±99.7 mm2, p\u3c0.001) and a larger volume (198.7±66.9 mm3 vs 145.0±65.9 mm3, p=0.001). Both decreased significantly over wear time, independent of angle. There was a significant difference in TAI (angled, 9.1±4.0 mm2 vs straight, 14.3±8.6 mm2, p\u3c0.001) and ILT (angled, 0.7±0.4 vs straight, 1.2±0.7 mm, p\u3c0.001). pmax (p=0.005) and AUC (p=0.014) were lower using angled IIS. As ILT increased, pmax increased, while SA and V decreased.
Conclusions: The progression of the ITR directly affected bolus shape and tubing pressure. Although straight insertion is clinically preferred, our data suggest that an angled IIS elicits lower grades of ITR and delivers a bolus with lower tubing pressure and greater SA and V. The subcutaneous environment plays a crucial role in IIS longevity, and the insertion angle needs to be considered in future IIS designs and clinical trials
Herding predators using swarm intelligence
Swarm intelligence, a nature-inspired concept that includes multiplicity, stochasticity, randomness, and messiness is emergent in most real-life problem-solving. The concept of swarming can be integrated with herding predators in an ecological system. This paper presents the development of stabilizing velocity-based controllers for a Lagrangian swarm of n∈N individuals, which are supposed to capture a moving target (intruder). The controllers are developed from a Lyapunov function, total potentials, designed via Lyapunov-based control scheme (LbCS) falling under the classical approach of artificial potential fields method. The interplay of the three central pillars of LbCS, which are safety, shortness, and smoothest course for motion planning, results in cost and time effectiveness and efficiency of velocity controllers. Computer simulations illustrate the effectiveness of control laws
Magnetization hysteresis and time decay measurements in FeSeTe : Evidence for fluctuation in mean free path induced pinning
We present results of magnetic measurements relating to vortex phase diagram
in a single crystal of FeSeTe which displays second
magnetization peak anomaly for . The possible role of the
crystalline anisotropy on vortex pinning is explored via magnetic torque
magnetometry. We present evidence in favor of pinning related to spatial
variations of the charge carrier mean free path leading to small bundle vortex
pinning by randomly distributed (weak) pinning centers for both
and . This is further corroborated using magnetization data for in a single crystal of FeSeTe. Dynamical
response across second magnetization peak (SMP) anomaly in
FeSeTe has been compared with that across the well researched
phenomenon of peak effect (PE) in a single crystal of CeRu.Comment: 11 figures, provided additional data in another sample, added Fig.
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Strain self-sensing tailoring in functionalised carbon nanotubes/epoxy nanocomposites in response to electrical resistance change measurement
Carbon nanotubes (CNTs) are inherently multifunctional, conductive and possess piezo-resistive characteristics. Aiming at the multi-functionality of materials, nanocomposites made of epoxy resin with embedded CNTs are a promising solution for strain self-sensing applications. A critical parameter to achieve repeatable and reliable measure is the CNTs dispersion state in the resin. This study investigated the effect of CNTs concentration (0.01 wt% and 0.1 wt%), with different loading of surfactant Triton X-100, (0.0%, 0.2%, 0.5% and 1.0%) on strain sensing in terms of sensitivity and linearity based on electrical resistance data. The CNTs were synthesised directly using an injection floating catalyst chemical vapor deposition (ICCVD) process and their quality was characterised by Raman spectroscopy and scanning electron microscopy. Only the epoxy modfied with 0.1 wt% CNTs exhibited sufficient piezo-resistivity for the resistance measurements, and those with 0.01 wt% CNTs did not show sufficiently measurable conductivity so were excluded in our study, since their CNTs were highly entangled, and conductive network failed to be established. It was observed that, with 0.1 wt% CNTs, adding 0.5% content of the surfactant improved gauge factor. With more content of the surfactant (1.0 %), surprisingly, we observed a drop of gauge factor by the order of two. Therefore, by comparing the conductivity change between 1.0% and 0.5% surfactant, we postulated that the relatively high content surfactant has reached critical micelle concentration, and negatively affects CNTs dispersion state. The research presented in this article shows that moderate content of surfactant could improve piezoresistivity gauge factor while excessive surfactant could cause adverse effect
GW627368X inhibits proliferation and induces apoptosis in cervical cancer by interfering with EP4/EGFR interactive signaling
PGE2, the major product of cyclooxygenases implicated in carcinogenesis, is significantly upregulated in cervical cancer. PGE2 via prostanoid receptor EP4 stimulates proliferation and motility while inhibiting apoptosis and immune surveillance. It promotes angiogenesis by stimulating the production of pro-angiogenic factors. The present study demonstrates GW627368X, a highly selective competitive EP4 antagonist, which hinders cervical cancer progression by inhibiting EP4/Epithelial Growth Factor Receptor (EGFR) interactive signaling. GW627368X reduced Protein Kinase A (PKA) phosphorylation which in turn leads to decreased cAMP response element-binding protein (CREB) activation. Decreased PKA phosphorylation also directly enhanced Bax activity and in part reduced glycogen synthase kinase 3 (GSK3)β phosphorylation. Owing to the interactive signaling between EP4 and EGFR, GW627368X lowered EGFR phosphorylation in turn reducing Akt, Mitogen-activated Protein Kinase (MAPK) and GSK3β activity significantly. Sublethal dose of GW627368X was found to reduce the nuclear translocation of β-catenin in a time dependent manner along with time-dependent decrease in cytoplasmic as well as whole-cell β-catenin. Decreased CREB and β-catenin transcriptional activity restricts the aberrant transcription of key genes like EP4, cyclooxygenase (COX)-2, vascular endothelial growth factor and c-myc, which ultimately control cell survival, proliferation and angiogenesis. Reduced activity of EGFR resulted in enhanced expression of 15-hydroxyprostaglandin dehydrogenase increasing PGE2 degradation thereby blocking a positive feedback loop. In xenograft model, dose-dependent decrease in cancer proliferation was observed characterized by reduction in tumor mass and volume and a marked decrease in Ki67 expression. A diminished CD31 specific staining signified decreased tumor angiogenesis. Reduced expression of pAkt, pMAPK, pEGFR and COX-2 validated in vitro results. GW627368X therefore effectively inhibits tumor survival, motility, proliferation and angiogenesis by blocking EP4/EGFR interactive signaling. EP4 is a potent therapeutic target in cervical cancer and can be explored in combination with conventional therapies to attain superior outcomes and to overcome complications associated with organ toxicities, therapeutic resistance and disease relapse
The Effect of Zinc Oxide on DLP Hybrid Composite Manufacturability and Mechanical-Chemical Resistance
The widespread use of epoxy resin (ER) in industry, owing to its excellent properties, aligns with the global shift toward greener resources and energy-efficient solutions, where utilizing metal oxides in 3D printed polymer parts can offer extended functionalities across various industries. ZnO concen-trations in polyurethane acrylate composites impacted adhesion and thickness of DLP samples, with 1 wt.% achieving a thickness of 3.99 ± 0.16 mm, closest to the target thickness of 4 mm, while 0.5 wt.% ZnO samples exhibited the lowest deviation in average thickness (±0.03 mm). Tensile stress in digital light processed (DLP) composites with ZnO remained consistent, ranging from 23.29 MPa (1 wt.%) to 25.93 MPa (0.5 wt.%), with an increase in ZnO concentration causing a reduction in tensile stress to 24.04 MPa and a decrease in the elastic modulus to 2001 MPa at 2 wt.% ZnO. The produced DLP samples, with their good corrosion resistance in alkaline environments, are well-suited for ap-plications as protective coatings on tank walls. Customized DLP techniques can enable their effec-tive use as structural or functional elements, such as in Portland cement concrete walls, floors and ceilings for enhanced durability and performanc
Soil Liquefaction Potential in Different Seismic Zones of Bihar, India
Liquefaction potential analysis for the liquefiable as well as non-liquefiable soils of Bihar state has been performed in this paper based on the actual field data from three seismic zones, i.e. zone III, zone IV, and zone V. The analysis has been performed following the simplified procedure given in [1] and later modified in [2]. The results show that districts under seismic zone III are comparatively more resistant to liquefaction in most cases, districts of zone IV are relatively more prone to liquefaction up to a few depths, and districts of zone V are most liquefiable. Liquefaction resistance is primarily depending upon the fine content of soil and SPT N-values
Smart Face Masks for Covid-19 Pandemic Management: A Concise Review of Emerging Architectures, Challenges and Future Research Directions
Smart sensing technology has been playing tremendous roles in digital healthcare management over time with great impacts. Lately, smart sensing has awoken the world by the advent of Smart Face Masks (SFM) in the global fight against the deadly Coronavirus (Covid-19) pandemic. In turn, a number of research studies on innovative SFM architectures and designs are emerging. However, there is currently no study that has systematically been conducted to identify and comparatively analyze the emerging architectures and designs of SFMs, their contributions, socio-technological implications, and current challenges. In this paper, we investigate the emerging SFMs in response to Covid-19 pandemic and provide a concise review of their key features and characteristics, design, smart technologies, and architectures. We also highlight and discuss the socio-technological opportunities posed by the use of SFMs and finally present directions for future research. Our findings reveal four key features that can be used to evaluate SFMs to include reusability, self-power generation ability, energy awareness and aerosol filtration efficiency. We discover that SFM has potential for effective use in human tracking, contact tracing, disease detection and diagnosis or in monitoring asymptotic populations in future pandemics. Some SFMs have also been carefully designed to provide comfort and safety when used by patients with other respiratory diseases or comorbidities. However, some identified challenges include standards and quality control, ethical, security and privacy concerns
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