9 research outputs found
Revealing the metabonomic variation of esophageal cancer using 1H-NMR spectroscopy and its association with the clinic pathological characteristics.
No full textMultiple Structural and Epigenetic Defects in the Human Leukocyte Antigen Class I Antigen Presentation Pathway in a Recurrent Metastatic Melanoma Following Immunotherapy
No full textHLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma
No full textTumour cells can evade the immune system by dysregulation of human leukocyte antigens (HLA-I). Low quantity and/or altered quality of HLA-I cell surface expression is the result of either HLA-I alterations or dysregulations of proteins of the antigen-processing machinery (APM). Tapasin is an APM protein dedicated to the maturation of HLA-I and dysregulation of tapasin has been linked to higher malignancy in several different tumours
β-Catenin and NF-κB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer
No full textHLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma
No full textBrucella spp. Lumazine Synthase Induces a TLR4-Mediated Protective Response against B16 Melanoma in Mice
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