127 research outputs found

    Severe Dyspnea due to Pulmonary Metastasis of Renal Cell Carcinoma: Is Cytoreductive Surgery of Value?

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    Here, we present a case in which cytoreductive surgery, like left radical nephrectomy, was effective in the treatment of pulmonary metastases and para-aortic metastases from renal cell carcinoma. A 28-year-old man underwent left radical nephrectomy with pulmonary metastasectomy for the diagnosis of metastatic left renal cell carcinoma. The histologic diagnosis was clear cell carcinoma G2, pT3N1M1. He subsequently underwent i.m. administration of IFN-α, 5 million units per day for 30 days. The nasal oxygen mask was weaned gradually, and the chest tube was removable due to cessation of the continuous production of pleural fluid. The patient was well until one year after operation

    The potential use of organosilane water soluble nanomaterials as water vapor diffusion retarders for wood

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    The retarding effect of organosilane water soluble nanomaterials (nano-zycosil and nano-zycofil) on water vapor diffusion through poplar wood (P.nigra) was evaluated in comparison with that of clear coatings (sealer and nitrocellulose lacquer and polyester lacquer) using cup and sorption methods.  Two drying methods were applied to dry the nanomaterials -coated substrates: oven drying at temperature of 103 ± 2 °C for 24 h. and climatically drying at temperature of 25 °C and relative humidity of 65% for 20 minutes. The results showed that both coating materials decreased the water vapor diffusion rate through the wood. The sealer and nitrocellulose lacquer coating represented a stronger effect on the diffusion coefficient of wood compared to the other coatings. In this case, the nano-zycosil represented a better performance compared to the nano-zycofil. Furthermore, the drying method of the nanomaterials -coated substrates can impact the nanomaterials performance. The water vapor diffusion through the oven-dried substrates was faster than that through the climatically dried ones

    The hypoglycemic effect of Juglans regia leaves aqueous extract in diabetic patients: A first human trial

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    BACKGROUND: Juglans regia L. (J. regia ) is one of the medicinal plants traditionally used for treatment of diabetes in Iranian medicine. The effect of this plant has already been investigated on animal models; however, this is the first study conducted on human subjects. The aim of this study is to investigate the hypoglycemic effect of J. regia leaves aqueous extract in type 2 diabetes patients. Fifty eight Iranian male and female patients with type 2 diabetes were enrolled. The patients were randomly allocated into two groups. One group (n = 30) received J. regia leaves extract while the other group (n = 28) received placebo. Fasting blood samples were collected at the beginning of the study and after two months for determination of HbA1c and blood glucose level as a main outcome and insulin, SGOT, SGPT, and ALP level as secondary outcome. RESULTS: Our analysis showed that serum fasting HbA1C and blood glucose levels were significantly decreased and the insulin level was increased in patients in the J. regia arm. CONCLUSIONS: The results indicate that J. regia aqueous extract favorably affects blood levels of glucose, insulin and HbA1C in type 2 diabetic patients

    Investigation of Adhesion Behavior of Aluminum Laminates /Carbon Fiber/ High Silica Fiber by Phenol Resins

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    Fiber‐metal laminate is a material constituted of composite laminate and metal sheets, whose mechanical properties can be tailored by varying the thickness, the number of layers and bonding type. For this reason, in this research, strength test, adhesion test and flux test for a sandblasted and etched aluminum sheet that contained a seven-layer composite with 2 types of adhesion treatment (phenol adhesive/resin of composite material) and front side composite layup (High-silica/High-silica+Carbon) were investigated. It was found that the above-mentioned factors influenced the flexural strength of FML; precisely, the presence of an adhesive layer between the composite plies and the metal sheet made the flexural strength decrease, while this mechanical parameter increased passing from two metal sheets to only one. The results show that the presence of carbon layer has led to the greatest increase in strength due to strong bonding. Also, the results of the flux test show that the behavior of the two samples is very close to each other

    Amniotic Membrane Transplantation for Persistent Epithelial Defects and Ulceration due to Pseudomonas Keratitis in a Rabbit Model

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    Purpose: The use of amniotic membrane has been suggested in the treatment ofinfectious keratitis for its intrinsic anti-infective properties probably mediated by its antiinflammatory effects. The aim of this study was to investigate the effect of amniotic membrane transplantation (AMT) along with ciprofloxacin to cure the primary stages of Pseudomonas keratitis. Methods: In total, 28 rabbits were selected and divided in four groups as follows: group 1 as control, group 2 with amniotic membrane, group 3 with ciprofloxacin, and group 4 with amniotic membrane combined with ciprofloxacin. About 0.05 cc suspension of Pseudomonas aeruginosa, 27853 ATCC was injected into corneal stroma. Results: The results showed groups of AMT, AMT + ciprofloxacin, and ciprofloxacin had 0% perforation while the control group had 85.6%. Average infiltration of 5.5 mm was observed in ciprofloxacin group, 5 mm in AMT + ciprofloxacin group, 24 mm in AMT group, and finally 23.75 mm for control. Amniotic membrane showed to be effective in prevention of cornea perforation as well as remission of Pseudomonas keratitis. There was no significant difference between ciprofloxacin groups in comparison with ciprofloxacin + AMT group. However, regarding the anti-inflammatory effect, the process of improvement of inflammation in ciprofloxacin + AMT group was faster. Conclusion: Transplantation of amniotic membrane in the primary stages of Pseudomonas keratitis treatment remarkably prevents the disease and it can be used to control its process

    Amniotic Membrane Transplantation for Persistent Epithelial Defects and Ulceration due to Pseudomonas Keratitis in a Rabbit Model

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    Purpose: The use of amniotic membrane has been suggested in the treatment of infectious keratitis for its intrinsic anti-infective properties probably mediated by its antiinflammatory effects. The aim of this study was to investigate the effect of amniotic membrane transplantation (AMT) along with ciprofloxacin to cure the primary stages of Pseudomonas keratitis. Methods: In total, 28 rabbits were selected and divided in four groups as follows: group 1 as control, group 2 with amniotic membrane, group 3 with ciprofloxacin, and group 4 with amniotic membrane combined with ciprofloxacin. About 0.05 cc suspension of Pseudomonas aeruginosa, 27853 ATCC was injected into corneal stroma. Results: The results showed groups of AMT, AMT + ciprofloxacin, and ciprofloxacin had 0% perforation while the control group had 85.6%. Average infiltration of 5.5 mm was observed in ciprofloxacin group, 5 mm in AMT + ciprofloxacin group, 24 mm in AMT group, and finally 23.75 mm for control. Amniotic membrane showed to be effective in prevention of cornea perforation as well as remission of Pseudomonas keratitis. There was no significant difference between ciprofloxacin groups in comparison with ciprofloxacin + AMT group. However, regarding the anti-inflammatory effect, the process of improvement of inflammation in ciprofloxacin + AMT group was faster. Conclusion: Transplantation of amniotic membrane in the primary stages of Pseudomonas keratitis treatment remarkably prevents the disease and it can be used to control its process. Keywords: Ciprofloxacin; Human Amniotic Membrane; Keratitis; Pseudomonas aeruginosa; Rabbi
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