98 research outputs found
ΠΠ½Π°Π»ΡΠ· ΠΊΡΠ»ΡΠΊΡΡΠ½ΠΈΡ ΡΠ° ΡΠΊΡΡΠ½ΠΈΡ Ρ Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊ Π΄ΠΈΠ½Π°ΠΌΡΠΊΠΈ Π½Π°ΡΠΊΠΎΠ²ΠΈΡ ΠΊΠ°Π΄ΡΡΠ² Π²ΠΈΡΠΎΡ ΠΊΠ²Π°Π»ΡΡΡΠΊΠ°ΡΡΡ Π£ΠΊΡΠ°ΡΠ½ΠΈ
ΠΠ±Π³ΠΎΠ²ΠΎΡΡΡΡΡΡΡ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠ° ΠΊΡΠ»ΡΠΊΡΡΠ½ΠΈΡ
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Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊ ΡΠ° ΡΠ½Π΄ΠΈΠΊΠ°ΡΠΎΡΡΠ² ΡΠΊΠΎΡΡΡ Π½Π°ΡΠΊΠΎΠ²ΠΎ-ΠΊΠ°Π΄ΡΠΎΠ²ΠΎΠ³ΠΎ ΠΏΠΎΡΠ΅Π½ΡΡΠ°Π»Ρ Π½Π°ΡΠΊΠΈ, ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΠΈ ΡΡ
ΠΎΡΡΠ½ΠΊΠΈ. ΠΠ°Π²Π΅Π΄Π΅Π½ΠΎ ΠΊΡΠ»ΡΠΊΡΡΠ½Ρ ΠΎΡΡΠ½ΠΊΡ Π΄ΠΈΠ½Π°ΠΌΡΠΊΠΈ ΡΠ° ΡΡΡΠ°ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°Π½Ρ Π½Π°ΡΠΊΠΎΠ²ΠΎ-ΠΊΠ°Π΄ΡΠΎΠ²ΠΎΠ³ΠΎ ΠΏΠΎΡΠ΅Π½ΡΡΠ°Π»Ρ Π²ΠΈΡΠΎΡ ΠΊΠ²Π°Π»ΡΡΡΠΊΠ°ΡΡΡ Π£ΠΊΡΠ°ΡΠ½ΠΈ, ΠΎΡΡΠ½ΠΊΡ Π΄ΠΈΠ½Π°ΠΌΡΠΊΠΈ ΡΠ° ΡΡΡΠ°ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°Π½Ρ ΠΉΠΎΠ³ΠΎ ΡΠΊΡΡΠ½ΠΈΡ
ΠΏΠΎΠΊΠ°Π·Π½ΠΈΠΊΡΠ².ΠΠ±ΡΡΠΆΠ΄Π°Π΅ΡΡΡ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠ° ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
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Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊ ΠΈ ΠΈΠ½Π΄ΠΈΠΊΠ°ΡΠΎΡΠΎΠ² ΠΊΠ°ΡΠ΅ΡΡΠ²Π° Π½Π°ΡΡΠ½ΠΎ-ΠΊΠ°Π΄ΡΠΎΠ²ΠΎΠ³ΠΎ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»Π° Π½Π°ΡΠΊΠΈ, ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΠΈ ΠΈΡ
ΠΎΡΠ΅Π½ΠΊΠΈ. ΠΡΠΈΠ²Π΅Π΄Π΅Π½Ρ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π΅Π½Π½Π°Ρ ΠΎΡΠ΅Π½ΠΊΠ° Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ ΠΈ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π½Π°ΡΡΠ½ΠΎ -ΠΊΠ°Π΄ΡΠΎΠ²ΠΎΠ³ΠΎ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»Π° Π²ΡΡΡΠ΅ΠΉ ΠΊΠ²Π°Π»ΠΈΡΠΈΠΊΠ°ΡΠΈΠΈ Π£ΠΊΡΠ°ΠΈΠ½Ρ, ΠΎΡΠ΅Π½ΠΊΠ° Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ ΠΈ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π΅Π³ΠΎ ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ.The discussion concerns the problem of quantitative parameters and indicators reflecting the quality of R&D personnel, and their measurement methodology. A quantitative measure is given of the dynamics, current conditions and qualitative indicators of the Ukrainian R&D personnel of the highest qualification
Simulations of the effects of tin composition gradients on the superconducting properties of Nb3Sn conductors
In powder-in-tube (PIT) Nb3Sn composites, the A15 phase forms between a
central tin-rich core and a coaxial Nb tube, thus causing the tin content and
superconducting properties to vary with radius across the A15 layer. Since this
geometry is also ideal for magnetic characterization of the superconducting
properties with the field parallel to the tube axis, a system of concentric
shells with varying tin content was used to simulate the superconducting
properties, the overall severity of the Sn composition gradient being defined
by an index N. Using well-known scaling relationships and property trends
developed in an earlier experimental study, the critical current density for
each shell was calculated, and from this the magnetic moment of each shell was
found. By summing these moments, experimentally measured properties such as
pinning-force curves and Kramer plots could be simulated. We found that
different tin profiles have only a minor effect on the shape of Kramer plots,
but a pronounced effect on the irreversibility fields defined by the
extrapolation of Kramer plots. In fact, these extrapolated values H_K are very
close to a weighted average of the superconducting properties across the layer
for all N. The difference between H_K and the upper critical field commonly
seen in experiments is a direct consequence of the different ways measurements
probe the simulated Sn gradients. Sn gradients were found to be significantly
deleterious to the critical current density Jc, since reductions to both the
elementary pinning force and the flux pinning scaling field H_K compound the
reduction in Jc. The simulations show that significant gains in Jc of Nb3Sn
strands might be realized by circumventing strong compositional gradients of
tin.Comment: 10 pages, 8 figures, 2 tables, submitted to J. Appl. Phy
Comparing unilateral and bilateral upper limb training: The ULTRA-stroke program design
<p>Abstract</p> <p>Background</p> <p>About 80% of all stroke survivors have an upper limb paresis immediately after stroke, only about a third of whom (30 to 40%) regain some dexterity within six months following conventional treatment programs. Of late, however, two recently developed interventions - constraint-induced movement therapy (CIMT) and bilateral arm training with rhythmic auditory cueing (BATRAC) - have shown promising results in the treatment of upper limb paresis in chronic stroke patients. The ULTRA-stroke (acronym for Upper Limb TRaining After stroke) program was conceived to assess the effectiveness of these interventions in subacute stroke patients and to examine how the observed changes in sensori-motor functioning relate to changes in stroke recovery mechanisms associated with peripheral stiffness, interlimb interactions, and cortical inter- and intrahemispheric networks. The present paper describes the design of this single-blinded randomized clinical trial (RCT), which has recently started and will take several years to complete.</p> <p>Methods/Design</p> <p>Sixty patients with a first ever stroke will be recruited. Patients will be stratified in terms of their remaining motor ability at the distal part of the arm (i.e., wrist and finger movements) and randomized over three intervention groups receiving modified CIMT, modified BATRAC, or an equally intensive (i.e., dose-matched) conventional treatment program for 6 weeks. Primary outcome variable is the score on the Action Research Arm test (ARAT), which will be assessed before, directly after, and 6 weeks after the intervention. During those test sessions all patients will also undergo measurements aimed at investigating the associated recovery mechanisms using haptic robots and magneto-encephalography (MEG).</p> <p>Discussion</p> <p>ULTRA-stroke is a 3-year translational research program which aims (1) to assess the relative effectiveness of the three interventions, on a group level but also as a function of patient characteristics, and (2) to delineate the functional and neurophysiological changes that are induced by those interventions.</p> <p>The outcome on the ARAT together with information about changes in the associated mechanisms will provide a better understanding of how specific therapies influence neurobiological changes, and which post-stroke conditions lend themselves to specific treatments.</p> <p>Trial Registration</p> <p>The ULTRA-stroke program is registered at the Netherlands Trial Register (NTR, <url>http://www.trialregister.nl</url>, number NTR1665).</p
Impact of early applied upper limb stimulation: The EXPLICIT-stroke programme design
Main claims of the literature are that functional recovery of the paretic upper limb is mainly defined within the first month post stroke and that rehabilitation services should preferably be applied intensively and in a task-oriented way within this particular time window. EXplaining PLastICITy after stroke (acronym EXPLICIT-stroke) aims to explore the underlying mechanisms of post stroke upper limb recovery. Two randomized single blinded trials form the core of the programme, investigating the effects of early modified Constraint-Induced Movement Therapy (modified CIMT) and EMG-triggered Neuro-Muscular Stimulation (EMG-NMS) in patients with respectively a favourable or poor probability for recovery of dexterity.BioMechanical EngineeringMechanical, Maritime and Materials Engineerin
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