486 research outputs found
The stabilization of thiepin by substitution
Resonance energies of 430 substituted thiepins have been calculated using a simple HĂŒckel method described before. The results predict that thiepins substituted with electron-withdrawing groups (methoxycarbonyl and fluorine) will be less antiaromatic than the parent thiepin. Thus the calculated REPE of the only known type of monocyclic thiepin viz. 3,4 - bis(methoxycarbonyl) - 5 pyrrolidinothiepin (-0.007ÎČ) is less negative than that of the parent thiepin
Systems of Hess-Appel'rot type
We construct higher-dimensional generalizations of the classical
Hess-Appel'rot rigid body system. We give a Lax pair with a spectral parameter
leading to an algebro-geometric integration of this new class of systems, which
is closely related to the integration of the Lagrange bitop performed by us
recently and uses Mumford relation for theta divisors of double unramified
coverings. Based on the basic properties satisfied by such a class of systems
related to bi-Poisson structure, quasi-homogeneity, and conditions on the
Kowalevski exponents, we suggest an axiomatic approach leading to what we call
the "class of systems of Hess-Appel'rot type".Comment: 40 pages. Comm. Math. Phys. (to appear
A Full Shell Model Study of a~=~48 Nuclei
Exact diagonalizations with a minimally modified realistic force lead to
detailed agreement with measured level schemes and electromagnetic transitions
in Ca, Sc, Ti, V, Cr and Mn.
Gamow-Teller strength functions are systematically calculated and reproduce the
data to within the standard quenching factor. Their fine structure indicates
that fragmentation makes much strength unobservable. As a by-product, the
calculations suggest a microscopic description of the onset of rotational
motion. The spectroscopic quality of the results provides strong arguments in
favour of the general validity of monopole corrected realistic forces, which is
discussed.Comment: 30 pages, LaTeX with epsf.sty, 14 Postscript figures included and
compressed using uufiles. Completely new version of previous preprint
nucl-th/9307001. FTUAM-93/01, CRN/PT 93-3
High School Exit Examinations: When Do Learning Effects Generalize?
This paper reviews international and domestic evidence on the effects of three types of high school exit exam systems: voluntary curriculum-based external exit exams, universal curriculum-based external exit exam systems and minimum competency tests that must be passed to receive a regular high school diploma. The nations and provinces that use Universal CBEEES (and typically teacher grades as well) to signal student achievement have significantly higher achievement levels and smaller differentials by family background than otherwise comparable jurisdictions that base high stakes decisions on voluntary college admissions tests and/or teacher grades. The introduction of Universal CBEEES in New York and North Carolina during the 1990s was associated with large increases in math achievement on NAEP tests. Research on MCTs and high school accountability tests is less conclusive because these systems are new and have only been implemented in one country. Cross-section studies using a comprehensive set of controls for family background have not found that students in MCT states score higher on audit tests like the NAEP that carry no stakes for the test taker. The analysis reported in table 1 tells us that the five states that introduced MCTs during the 1990s had significantly larger improvements on NAEP tests than states that made no change in their student accountability regime. The gains, however, are smaller than for the states introducing Universal CBEEES. New York and North Carolina. The most positive finding about MCTs is that students in MCT states earn significantly more during the first eight years after graduation than comparable students in other states suggesting that MCTs improve employer perceptions of the quality of the recent graduates of local high schools
The RNA workbench: best practices for RNA and high-throughput sequencing bioinformatics in Galaxy
RNA-based regulation has become a major research topic in molecular biology. The analysis of epigenetic and expression data is therefore incomplete if RNA-based regulation is not taken into account. Thus, it is increasingly important but not yet standard to combine RNA-centric data and analysis tools with other types of experimental data such as RNA-seq or ChIP-seq. Here, we present the RNA workbench, a comprehensive set of analysis tools and consolidated workflows that enable the researcher to combine these two worlds. Based on the Galaxy framework the workbench guarantees simple access, easy extension, flexible adaption to personal and security needs, and sophisticated analyses that are independent of command-line knowledge. Currently, it includes more than 50 bioinformatics tools that are dedicated to different research areas of RNA biology including RNA structure analysis, RNA alignment, RNA annotation, RNA-protein interaction, ribosome profiling, RNA-seq analysis and RNA target prediction. The workbench is developed and maintained by experts in RNA bioinformatics and the Galaxy framework. Together with the growing community evolving around this workbench, we are committed to keep the workbench up-to-date for future standards and needs, providing researchers with a reliable and robust framework for RNA data analysis. Availability: The RNA workbench is available at https://github.com/bgruening/galaxy-rna-workbench
MRI of Breast Lesions
In Magnetic Resonance Mammography (MRM) high spatial as well as temporal resolution is of utmost importance for differentiating between malignant and benign lesions. Therefore, a soâcalled dynamic technique (i.e., the repetitive imaging of the same slices before and in short time intervals after the injection of contrast medium) is essential to detect the differences in initial enhancements between malignant and benign lesions which are reflected by the tumorangiogenetic vascular network of malignant lesions. This unit presents a basic protocol and several alternate protocols for dynamic MRM.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/145284/1/cpmia2101.pd
A scale-based framework to understand the promises, pitfalls and paradoxes of irrigation efficiency to meet major water challenges
An effective placement of irrigation efficiency in water management will contribute towards meeting the pre-eminent global water challenges of our time such as addressing water scarcity, boosting crop water productivity and reconciling competing water needs between sectors. However, although irrigation efficiency may appear to be a simple measure of performance and imply dramatic positive benefits, it is not straightforward to understand, measure or apply. For example, hydrological understanding that irrigation losses recycle back to surface and groundwater in river basins attempts to account for scale, but this generalisation cannot be readily translated from one location to another or be considered neutral for farmers sharing local irrigation networks. Because irrigation efficiency (IE) motives, measures, effects and technologies play out at different scales for different people, organisations and purposes, and losses differ from place to place and over time, IE is a contested term, highly changeable and subjective. This makes generalisations for science, management and policy difficult. Accordingly, we propose new definitions for IE and irrigation hydrology and introduce a framework, termed an âirrigation efficiency matrixâ, comprising five spatial scales and ten dimensions to understand and critique the promises, pitfalls and paradoxes of IE and to unlock its utility for addressing contemporary water challenges
The RNA workbench: Best practices for RNA and high-throughput sequencing bioinformatics in Galaxy
RNA-based regulation has become a major research topic in molecular biology. The analysis of epigenetic and expression data is therefore incomplete if RNA-based regulation is not taken into account. Thus, it is increasingly important but not yet standard to combine RNA-centric data and analysis tools with other types of experimental data such as RNA-seq or ChIP-seq. Here, we present the RNA workbench, a comprehensive set of analysis tools and consolidated workflows that enable the researcher to combine these two worlds. Based on the Galaxy framework the workbench guarantees simple access, easy extension, flexible adaption to personal and security needs, and sophisticated analyses that are independent of command-line knowledge. Currently, it includes more than 50 bioinformatics tools that are dedicated to different research areas of RNA biology including RNA structure analysis, RNA alignment, RNA annotation, RNA-protein interaction, ribosome profiling, RNA-seq analysis and RNA target prediction. The workbench is developed and maintained by experts in RNA bioinformatics and the Galaxy framework. Together with the growing community evolving around this workbench, we are committed to keep the workbench up-to-date for future standards and needs, providing researchers with a reliable and robust framework for RNA data analysis
Colossal dielectric constants in transition-metal oxides
Many transition-metal oxides show very large ("colossal") magnitudes of the
dielectric constant and thus have immense potential for applications in modern
microelectronics and for the development of new capacitance-based
energy-storage devices. In the present work, we thoroughly discuss the
mechanisms that can lead to colossal values of the dielectric constant,
especially emphasising effects generated by external and internal interfaces,
including electronic phase separation. In addition, we provide a detailed
overview and discussion of the dielectric properties of CaCu3Ti4O12 and related
systems, which is today's most investigated material with colossal dielectric
constant. Also a variety of further transition-metal oxides with large
dielectric constants are treated in detail, among them the system La2-xSrxNiO4
where electronic phase separation may play a role in the generation of a
colossal dielectric constant.Comment: 31 pages, 18 figures, submitted to Eur. Phys. J. for publication in
the Special Topics volume "Cooperative Phenomena in Solids: Metal-Insulator
Transitions and Ordering of Microscopic Degrees of Freedom
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