Dopamine: A Marker of Psychosis and Final Common Driver of Schizophrenia Psychosis

Our attempt to understand schizophrenia in neurochemical terms began with the landmark studies of Carlsson and Lindqvist (1) in the 1960s. The results of these studies, based on the action of chlorpromazine, were strengthened by the binding studies carried out in both Seeman's (2) and Synder's (3) laboratories, which showed that antipsychotic potency was correlated with dopamine D2 receptor binding. The one major exception to this correlation is clozapine, which appears to be the most effective available drug for treating schizophrenia symptoms. The most recent version of the resulting dopamine hypothesis suggests that genetic, environmental, and developmental variables play major etiological roles in schizophrenia, but that striatal dopamine presynaptic overactivity remains the final trigger resulting in psychosis.....

Scattering into the fifth dimension of N=4 super Yang-Mills

We study an alternative to dimensional regularisation of planar scattering amplitudes in N=4 super Yang-Mills theory by going to the Coulomb phase of the theory. The infrared divergences are regulated by masses obtained from a Higgs mechanism, allowing us to work in four dimensions. The corresponding string theory set-up suggests that the amplitudes have an exact dual conformal symmetry. The latter acts on the kinematical variables of the amplitudes as well as on the Higgs masses in an effectively five dimensional space. We confirm this expectation by an explicit calculation in the gauge theory. A consequence of this exact dual conformal symmetry is a significantly reduced set of scalar basis integrals that are allowed to appear in an amplitude. For example, triangle sub-graphs are ruled out. We argue that the study of exponentiation of amplitudes is simpler in the Higgsed theory because evanescent terms in the mass regulator can be consistently dropped. We illustrate this by showing the exponentiation of a four-point amplitude to two loops. Finally, we also analytically compute the small mass expansion of a two-loop master integral with an internal mass.Comment: 35 pages, many figures. v2: typos and references fixed. v3: minor changes, version to be published in JHE

Emergence of turbulence in an oscillating Bose-Einstein condensate

We report on the experimental observation of vortices tangle in an atomic BEC of Rb-87 atoms when an external oscillatory perturbation is introduced in the trap. The vortices tangle configuration is a signature of the presence of a turbulent regime in the cloud. We also show that this turbulent cloud has suppression of the aspect ratio inversion typically observed in quantum degenerate bosonic gases during free expansion. Instead, the cloud expands keeping the ratio between their axis constant. Turbulence in atomic superfluids may constitute an alternative system to investigate decay mechanisms as well as to test fundamental theoretical aspects in this field.Comment: accepted for Phys. Rev. Let

Polls and the political process: the use of opinion polls by political parties and mass media organizations in European post‐communist societies (1990–95)

Opinion polling occupies a significant role within the political process of most liberal-capitalist societies, where it is used by governments, parties and the mass media alike. This paper examines the extent to which polls are used for the same purposes in the post-communist countries of Central and Eastern Europe, and in particular, for bringing political elites and citizens together. It argues that these political elites are more concerned with using opinion polls for gaining competitive advantage over their rivals and for reaffirming their political power, than for devolving political power to citizens and improving the general processes of democratization

Generation of vortices and observation of Quantum Turbulence in an oscillating Bose-Einstein Condensate

We report on the experimental observation of vortex formation and production of tangled vortex distribution in an atomic BEC of Rb-87 atoms submitted to an external oscillatory perturbation. The oscillatory perturbations start by exciting quadrupolar and scissors modes of the condensate. Then regular vortices are observed finally evolving to a vortex tangle configuration. The vortex tangle is a signature of the presence of a turbulent regime in the cloud. We also show that this turbulent cloud has suppression of the aspect ratio inversion typically observed in quantum degenerate bosonic gases during free expansion.Comment: to appear in JLTP - QFS 200