183 research outputs found
Temporal pixel multiplexing for simultaneous high-speed, high-resolution imaging
We introduce an imaging modality that, by offsetting pixel-exposure times during capture of a single image frame, embeds temporal information in each frame. This allows simultaneous acquisition of full-resolution images at native detector frame rates and high-speed image sequences at reduced resolution, without increasing bandwidth requirements. We demonstrate this method using macroscopic and microscopic examples, including imaging calcium transients in heart cells at 250 Hz using a 10-Hz megapixel camera
First Physics Results at the Physical Pion Mass from Wilson Twisted Mass Fermions at Maximal Twist
We present physics results from simulations of QCD using dynamical
Wilson twisted mass fermions at the physical value of the pion mass. These
simulations were enabled by the addition of the clover term to the twisted mass
quark action. We show evidence that compared to previous simulations without
this term, the pion mass splitting due to isospin breaking is almost completely
eliminated. Using this new action, we compute the masses and decay constants of
pseudoscalar mesons involving the dynamical up and down as well as valence
strange and charm quarks at one value of the lattice spacing,
fm. Further, we determine renormalized quark masses as well as their
scale-independent ratios, in excellent agreement with other lattice
determinations in the continuum limit. In the baryon sector, we show that the
nucleon mass is compatible with its physical value and that the masses of the
baryons do not show any sign of isospin breaking. Finally, we compute
the electron, muon and tau lepton anomalous magnetic moments and show the
results to be consistent with extrapolations of older ETMC data to the
continuum and physical pion mass limits. We mostly find remarkably good
agreement with phenomenology, even though we cannot take the continuum and
thermodynamic limits.Comment: 45 pages, 15 figure
The Euler-Maruyama approximation for the absorption time of the CEV diffusion
A standard convergence analysis of the simulation schemes for the hitting
times of diffusions typically requires non-degeneracy of their coefficients on
the boundary, which excludes the possibility of absorption. In this paper we
consider the CEV diffusion from the mathematical finance and show how a weakly
consistent approximation for the absorption time can be constructed, using the
Euler-Maruyama scheme
Dynamical Mean-Field Theory
The dynamical mean-field theory (DMFT) is a widely applicable approximation
scheme for the investigation of correlated quantum many-particle systems on a
lattice, e.g., electrons in solids and cold atoms in optical lattices. In
particular, the combination of the DMFT with conventional methods for the
calculation of electronic band structures has led to a powerful numerical
approach which allows one to explore the properties of correlated materials. In
this introductory article we discuss the foundations of the DMFT, derive the
underlying self-consistency equations, and present several applications which
have provided important insights into the properties of correlated matter.Comment: Chapter in "Theoretical Methods for Strongly Correlated Systems",
edited by A. Avella and F. Mancini, Springer (2011), 31 pages, 5 figure
Supersolid state of ultracold fermions in an optical lattice
We study ultracold fermionic atoms trapped in an optical lattice with
harmonic confinement by means of the dynamical mean-field approximation. It is
demonstrated that a supersolid state, where an s-wave superfluid coexists with
a density-wave state with a checkerboard pattern, is stabilized by attractive
onsite interactions on a square lattice. Our new finding here is that a
confining potential plays an invaluable role in stabilizing the supersolid
state. We establish a rich phase diagram at low temperatures, which clearly
shows how the insulator, the density wave and the superfluid compete with each
other to produce an intriguing domain structure. Our results shed light on the
possibility of the supersolid state in fermionic optical lattice systems.Comment: 5 pages, 4 figure
Communication in cancer genetic counselling: does it reflect counselees' previsit needs and preferences?
This study sought to describe counsellorācounselee interaction during initial cancer genetic counselling consultations and to examine whether the communication reflects counselees' previsit needs. A total of 130 consecutive counselees, referred mainly for breast or colon cancer, completed a questionnaire before their first appointment at a genetic clinic. Their visit was videotaped. Counselee and counsellor verbal communications were analysed and initiative to discuss 11 genetics-specific conversational topics was assessed. The content of the visit appeared relatively standard. Overall, counselees had a stronger psychosocial focus than counsellors. Counsellors directed the communication more and initiated the discussion of most of the topics assessed. Counselees did not appear to communicate readily in a manner that reflected their previsit needs. Counsellors provided more psychosocial information to counselees in higher need for emotional support, yet did not enquire more about counselees' specific concerns. New counselees may be helped by receiving more information on the counselling procedure prior to their visit, and may be advised to prepare the visit more thoroughly so as to help them verbalise more their queries during the visit
Assessment of contractility in intact ventricular cardiomyocytes using the dimensionless āFrankāStarling Gainā index
This paper briefly recapitulates the FrankāStarling law of the heart, reviews approaches to establishing diastolic and systolic forceālength behaviour in intact isolated cardiomyocytes, and introduces a dimensionless index called āFrankāStarling Gainā, calculated as the ratio of slopes of end-systolic and end-diastolic forceālength relations. The benefits and limitations of this index are illustrated on the example of regional differences in Guinea pig intact ventricular cardiomyocyte mechanics. Potential applicability of the FrankāStarling Gain for the comparison of cell contractility changes upon stretch will be discussed in the context of intra- and inter-individual variability of cardiomyocyte properties
Bounding Mean First Passage Times in Population Continuous-Time Markov Chains
We consider the problem of bounding mean first passage times and reachability probabilities for the class of population continuous-time Markov chains, which capture stochastic interactions between groups of identical agents. The quantitative analysis of such models is notoriously difficult since typically neither state-based numerical approaches nor methods based on stochastic sampling give efficient and accurate results. Here, we propose a novel approach that leverages techniques from martingale theory and stochastic processes to generate constraints on the statistical moments of first passage time distributions. These constraints induce a semi-definite program that can be used to compute exact bounds on reachability probabilities and mean first passage times without numerically solving the transient probability distribution of the process or sampling from it. We showcase the method on some test examples and tailor it to models exhibiting multimodality, a class of particularly challenging scenarios from biology
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