Investigation and Characterization of Nitrazapropane‐, Oxapropane‐ and Trinitrazaheptane‐Bridged Nitro Esters

In this work, 1,3-dinitroxy-2-nitrazapropane and 1,7-dinitroxy-2,4,6-trinitrazaheptane were synthesized and investigated. Starting from hexamine, the open-chain compounds were prepared by a modified Bachmann procedure which is commonly used for the synthesis of hexogen (RDX) and octogen (HMX). All new compounds were characterized by NMR spectroscopy, X-ray diffraction, vibrational analysis and elemental analysis. Their thermal behavior was studied by differential thermal analysis (DTA) and thermogravimetric analysis (TGA). The sensitivities towards impact (IS) and friction (FS) were determined according to the BAM (Bundesanstalt für Materialforschung und -prüfung) standard method. Their energetic properties, which were determined from the energies of formation at the CBS-4 M level, were calculated using the EXPLO5 computer code. Moreover, 1,3-dinitroxy-2-oxapropane was synthesized and investigated. The various compounds were compared with each other and with the commonly used explosives in terms of their physicochemical properties and detonation behavior

Synthesis of Bridged Tetrazoles with Promising Properties and Potential Applications by a One‐Step Finkelstein Reaction

Numerous nitramine bridged compounds which show promising combinations of properties have already been identified in the area of energetic materials. In this work, four new nitrazapropane bridged tetrazoles, as well as four new trinitrazaheptane tetrazoles and three oxapropane bridged tetrazoles were synthesized and fully characterized. These new compounds can all be synthesized by a simple, one-step synthesis using Finkelstein conditions. All of these new energetic materials were characterized using NMR spectroscopy, single crystal X-ray diffraction, vibrational analysis and elemental analysis. The thermal behaviour of these compounds was studied by differential thermal analysis (DTA) and partly by thermogravimetric analysis (TGA). The BAM standard method was used to determine the sensitivities towards impact (IS) and friction (FS). The enthalpies of formation were calculated at the CBS-4M level, and the energetic performances were calculated using the EXPLO5 (V6.06.01) computer code. The properties of the new compounds were compared to each other as well as to the known energetic material RDX. Moreover, the iron(II) and copper(II) perchlorate complexes with 1,3-bis-1,1-tetrazolylnitrazapropane as ligand were prepared and investigated

A Microring Resonator Sensor for Sensitive Detection of 1,3,5-Trinitrotoluene (TNT)

A microring resonator sensor device for sensitive detection of the explosive 1,3,5-trinitrotoluene (TNT) is presented. It is based on the combination of a silicon microring resonator and tailored receptor molecules

Dynamic building stock modelling: Application to 11 European countries to support the energy efficiency and retrofit ambitions of the EU

A dynamic building stock model is applied to simulate the development of dwelling stocks in 11 European countries, over half of all European dwellings, between 1900 and 2050. The model uses time series of population and number of persons per dwelling, as well as demolition and renovation probability functions that have been derived for each country. The model performs well at simulating the long-term changes in dwelling stock composition and expected annual renovation activities. Despite differences in data collection and reporting, the modelled future trends for construction, demolition and renovation activities lead to similar patterns emerging in all countries. The model estimates future renovation activity due to the stock's need for maintenance as a result of ageing. The simulations show only minor future increases in the renovation rates across all 11 countries to between 0.6–1.6%, falling short of the 2.5–3.0% renovation rates that are assumed in many decarbonisation scenarios. Despite this, 78% of all dwellings could benefit from energy efficiency measures by 2050, either as they are constructed (31%) or undergo deep renovation (47%). However, as no more than one deep renovation cycle is likely on this timeframe, it is crucial to install the most energy efficient measures available at these opportunities.publishedVersio

Conducting intervention research through the Cancer Information Service: a feasibility study

PURPOSE/OBJECTIVES: To determine the feasibility of conducting trials of educational interventions regarding pain and quality of life (QOL) with people who call the National Cancer Institute's Cancer Information Service (CIS). DESIGN: Descriptive. SETTING: North Central CIS, located at the University of Wisconsin Comprehensive Cancer Center in Madison. SAMPLE: Callers to the North Central CIS who self-identified as people diagnosed with cancer or as family members or friends of people diagnosed with cancer were eligible. 102 people with cancer and 103 significant others answered questions concerning the feasibility of a pain study, and 101 significant others completed questions about the feasibility of a QOL study. METHODS: Eligible CIS callers were invited at the end of usual service to participate in a research study. Those who agreed were asked structured questions regarding pain or QOL. MAIN RESEARCH VARIABLES: Response rate, length of time to complete recruitment, concerns about reporting pain and using analgesics, concerns about QOL, demographic variables, and willingness to join a hypothetical study. FINDINGS: The majority of callers had concerns about pain and QOL, and the vast majority (78%-89%) of participants indicated a willingness to join a future educational intervention study. CONCLUSIONS: Using subjects recruited through CIS, conducting trials of brief telephone interventions designed to help patients overcome barriers to pain management or assist families in addressing QOL concerns may be feasible. IMPLICATIONS FOR NURSING: Researchers may wish to consider the opportunities afforded by collaborating with CIS colleagues in planning and conducting studies of educational interventions