19,498 research outputs found
A study of charge storage in silicon oxide resulting from non-penetrating electron irradiation
Charge storage in silicon dioxide resulting from electron irradiatio
Charge storage effects in Mylar resulting from electron irradiation, June 1965 - June 1966
Charge storage effects in Mylar from electron irradiatio
1.0 Mm Maps and Radial Density Distributions of Southern Hii/molecular Cloud Complexes
Several 1.0 continuum mapping observations were made of seven southern hemisphere h12/molecular cloud complexes with 65 arcsec resolution. The radial density distribution of the clouds with central luminosity sources was determined observationally. Strong similarities in morphology and general physical conditions were found to exist among all of the southern clouds in the sample
Measurements of elastohydrodynamic film thickness, wear and tempering behavior of high pressure oxygen turbopump bearings
The reusable design of the Space Shuttle requires a target life of 7.5 hours for the turbopumps of the Space Shuttle main engine (SSME). This large increase from the few hundred seconds required in single-use rockets has caused various problems with the bearings of the turbopumps. The berings of the high pressure oxygen turbopump (HPOTP) were of particular concern because of wear, spalling, and cage failures at service time well below the required 7.5 hours. Lubrication and wear data were developed for the bearings. Since the HPOTP bearings operate in liquid oxygen, conventional liquid lubricants cannot be applied. Therefore, solid lubricant coatings and lubricant transfer from the polytetrafluorethylene (FTFE) cage were the primary lubrication approaches for the bearings. Measurements were made using liquid nitrogen in a rolling disk machine to determine whether usable elastohydrodynamic films could be generated to assist in the bearing lubrication
Electromagnetic interferences from plasmas generated in meteoroids impacts
It is shown that the plasma, generated during an impact of a meteoroid with
an artificial satellite, can produce electromagnetic radiation below the
microwave frequency range. This interference is shown to exceed local noise
sources and might disturb regular satellite operations.Comment: 6 pages, no figures. This version macthes the published versio
Place Cell Networks in Pre-weanling Rats Show Associative Memory Properties from the Onset of Exploratory Behavior
Place cells are hippocampal pyramidal cells that are active when an animal visits a restricted area of the environment, and collectively their activity constitutes a neural representation of space. Place cell populations in the adult rat hippocampus display fundamental properties consistent with an associative memory network: the ability to 1) generate new and distinct spatial firing patterns when encountering novel spatial contexts or changes in sensory input ("remapping") and 2) reinstate previously stored firing patterns when encountering a familiar context, including on the basis of an incomplete/degraded set of sensory cues ("pattern completion"). To date, it is unknown when these spatial memory responses emerge during brain development. Here, we show that, from the age of first exploration (postnatal day 16) onwards, place cell populations already exhibit these key features: they generate new representations upon exposure to a novel context and can reactivate familiar representations on the basis of an incomplete set of sensory cues. These results demonstrate that, as early as exploratory behaviors emerge, and despite the absence of an adult-like grid cell network, the developing hippocampus processes incoming sensory information as an associative memory network
Growth control of GaAs nanowires using pulsed laser deposition with arsenic over pressure
Using pulsed laser ablation with arsenic over pressure, the growth conditions
for GaAs nanowires have been systematically investigated and optimized. Arsenic
over pressure with As molecules was introduced to the system by thermal
decomposition of polycrystalline GaAs to control the stoichiometry and shape of
the nanowires during growth. GaAs nanowires exhibit a variety of geometries
under varying arsenic over pressure, which can be understood by different
growth processes via vapor-liquid-solid mechanism. Single-crystal GaAs
nanowires with uniform diameter, lengths over 20 m, and thin surface oxide
layer were obtained and can potentially be used for further electronic
characterization
Anti-CD20 therapy depletes activated myelin-specific CD8+ T cells in multiple sclerosis.
CD8+ T cells are believed to play an important role in multiple sclerosis (MS), yet their role in MS pathogenesis remains poorly defined. Although myelin proteins are considered potential autoantigenic targets, prior studies of myelin-reactive CD8+ T cells in MS have relied on in vitro stimulation, thereby limiting accurate measurement of their ex vivo precursor frequencies and phenotypes. Peptide:MHC I tetramers were used to identify and validate 5 myelin CD8+ T cell epitopes, including 2 newly described determinants in humans. The validated tetramers were used to measure the ex vivo precursor frequencies and phenotypes of myelin-specific CD8+ T cells in the peripheral blood of untreated MS patients and HLA allele-matched healthy controls. In parallel, CD8+ T cell responses against immunodominant influenza epitopes were also measured. There were no differences in ex vivo frequencies of tetramer-positive myelin-specific CD8+ T cells between MS patients and control subjects. An increased proportion of myelin-specific CD8+ T cells in MS patients exhibited a memory phenotype and expressed CD20 compared to control subjects, while there were no phenotypic differences observed among influenza-specific CD8+ T cells. Longitudinal assessments were also measured in a subset of MS patients subsequently treated with anti-CD20 monoclonal antibody therapy. The proportion of memory and CD20+ CD8+ T cells specific for certain myelin but not influenza epitopes was significantly reduced following anti-CD20 treatment. This study, representing a characterization of unmanipulated myelin-reactive CD8+ T cells in MS, indicates these cells may be attractive targets in MS therapy
Determination of the Far-Infrared Cosmic Background Using COBE/DIRBE and WHAM Data
Determination of the cosmic infrared background (CIB) at far infrared
wavelengths using COBE/DIRBE data is limited by the accuracy to which
foreground interplanetary and Galactic dust emission can be modeled and
subtracted. Previous determinations of the far infrared CIB (e.g., Hauser et
al. 1998) were based on the detection of residual isotropic emission in skymaps
from which the emission from interplanetary dust and the neutral interstellar
medium were removed. In this paper we use the Wisconsin H-alpha Mapper (WHAM)
Northern Sky Survey as a tracer of the ionized medium to examine the effect of
this foreground component on determination of the CIB. We decompose the DIRBE
far infrared data for five high Galactic latitude regions into H I and H-alpha
correlated components and a residual component. We find the H-alpha correlated
component to be consistent with zero for each region, and we find that addition
of an H-alpha correlated component in modeling the foreground emission has
negligible effect on derived CIB results. Our CIB detections and 2 sigma upper
limits are essentially the same as those derived by Hauser et al. and are given
by nu I_nu (nW m-2 sr-1) < 75, < 32, 25 +- 8, and 13 +- 3 at 60, 100, 140, and
240 microns, respectively. Our residuals have not been subjected to a detailed
anisotropy test, so our CIB results do not supersede those of Hauser et al. We
derive upper limits on the 100 micron emissivity of the ionized medium that are
typically about 40% of the 100 micron emissivity of the neutral atomic medium.
This low value may be caused in part by a lower dust-to-gas mass ratio in the
ionized medium than in the neutral medium, and in part by a shortcoming of
using H-alpha intensity as a tracer of far infrared emission.Comment: 38 pages, 8 figures. Accepted for publication in Ap
An Unsettling Outcome: Why the Florida Supreme Court was Wrong to Ban all Settlement Evidence in Saleeby v. Rocky Elson Construction, Inc., 3 So. 3d 1078 (Fla. 2009)
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