Experimental investigations on alkali activated foam concrete with impure kaolin

Abstract. The main goal of this thesis was to produce foam concrete by using impure kaolinite coming from the mining industry of Finland. The purpose of making foam concrete was to use as light weight concrete in engineering applications such as thermal/ acoustical insulations and building blocks. The experimental part consists of two different sets of experiments. The first set of experiments involve fresh properties to determine fresh density, viscosity, yield stress and aeration rate and to find the behavior of sample in the fresh state before curing. The second set of experiments was the harden properties including the compressive strength and water absorption. The purpose for testing was to find the effect of H2O2, molarity of NaOH and the effect of surfactants. The purpose of our study was to check the application of impure kaolinite in the production of light weight foam concrete. Furthermore, XRD and FTIR analysis were carried out to determine the crystalline structure and the chemical properties of the Alkali activated kaolinite. Polarized microscope was used to get insight about the pore structure and the effect of different parameters on the pores structure and size. The main findings from the study is the possibility to use kaolinite without any processing and production of low temperature (400 ˚C) ceramic like concrete foam. The dosage of H2O2 was varied from 0.5 to 2%, it effected the hardened properties such as compressive strength as it goes from 20 MPa to 15 MPa. Furthermore, it effected the fresh properties of the material, especially the aeration rate. The aeration rate was increasing for all samples when the percentage of H2O2 was increased. The molarity of NaOH was an important factor that affected the water absorption. Microscopic studies showed that the pore structure varied between samples made without surfactants and those with surfactants, that explains the hardened properties of the aerated foam with impure kaolinite

Functional properties of enzymatically modified protein from fish waste

Fish flour from dried waste consisting of head, tail, fins and entrails was enzimatically hydrolysed using various proteases and the hydrolysate was spray dried. The functional properties such as water-fat absorption ratio, foaming and solubility index of the hydrolysates and fish flour revealed that some of the products might find significant uses in the food and/or cosmetics industry. Electrophoretic separation of the proteins from the fish flour and of the hydrolysates indicated that almost all the flour proteins are susceptible to proteolytic cleavage with the exception of one or two. The extent of degree of hydrolysis from 43-70.3% with a simultaneous decrease in unpleasant smell suggest an economical tool for minimizing odour pollution due to fish industry waste deterioration

Fiscal Policy and Its Role in Reducing Income Inequality: A CGE Analysis for Pakistan

Income inequality is one of the critical barriers to growth and development in most of the developing countries including Pakistan. Every third man in Pakistan falls below the poverty line1. Moreover, the budget deficit has also been a serious issue throughout the history of Pakistan‟s economy. The persistent budget deficit is the constant source of increasing poverty and deterioration of income distribution. Since deficit is financed by increasing indirect taxes and money supply, it causes the reduction in purchasing power and leads the masses towards poverty [Arif and Farooq (2011)]. Therefore, it is a dire need of the economy to have a good public policy such that it could reduce budget deficit, alleviate poverty and redistribute income. Malik and Saqib (1985) suggest that the resources of the economy can be distributed equally only through appropriate changes in the tax system. Fiscal policy can have a significant influence on removing the gap between haves and havenots both directly and indirectly. It directly affects the disposable income of individuals, whereas affecting their future earning capacities indirectl

High CD44 immunoexpression correlates with poor overall survival: Assessing the role of cancer stem cell markers in oral squamous cell carcinoma patients from the high-risk population of Pakistan

Oral squamous cell carcinoma (OSCC) is a top-ranked cancer in the Pakistani population, and patient survival has remained unchanged at ∼50% for several decades. Recent advances have claimed that a subset of tumour cells, called cancer stem cells (CSCs), are responsible for tumour progression, treatment resistance, and metastasis, which leads to a poor prognosis. This study investigated the impact of CSC markers expression on overall survival (OS) and disease-free survival (DFS) of OSCC patients. Materials and Methods. Immunohistochemistry was used to evaluate CD44, CD133, L1CAM, and SOX2 expression in a well-characterized cohort of 100 Pakistani patients with primary treatment naïve OSCC. The immunoreactivity for each marker was correlated with patient clinicopathologic characteristics, oral cancer risk chewing habits, and survival. The minimum follow-up time for all patients was five years, and survival estimates were calculated using the Kaplan-Meier method and Cox proportional hazards model. Results. In this cohort of 100 patients, there were 57 males and 43 females. The median OS and DFS time durations observed were 64 and 52.5 months, respectively. Positive expression for CD44, CD133, L1CAM, and SOX2 was observed in 33%, 23%, 41%, and 63% of patients. High CD44 expression correlated with decreased OS (P=0.047) but did not influence DFS. However, CD133, L1CAM, and SOX2 had no effect on either OS or DFS. Tonsils, nodal involvement, and AJCC stage were independent predictors of worse OS and DFS both. Conclusion. Of the CSC markers investigated here, only CD44 was a predictor for poor OS. CD44 was also associated with advanced AJCC and T stages. Interestingly, CD133 was significantly lower in patients who habitually consumed oral cancer risk factors

Nutritional status in patients with Hepatitis C

OBJECTIVE: To assess the nutritional status via the SGA (subjective global assessment) screening tool of patients at all stages of hepatitis C virus (HCV) liver disease. STUDY DESIGN: Descriptive study. PLACE AND DURATION OF STUDY: Out-patient Clinics of the Aga Khan University Hospital, Karachi, conducted from October 2009 to January 2011. METHODOLOGY: Patients with hepatitis C virus infection and their HCV-negative attendants were enrolled from the outpatient clinics, and categorized into 4 groups of 100 patients each: healthy controls (HC), those with chronic hepatitis C infection (CHC), compensated cirrhotics (CC) and decompensated cirrhotics (DC). The validated subjective global assessment (SGA) tool was used to assess nutritional status. RESULTS: A total of 400 patients were enrolled. Most of the patients in the HC group were class \u27A\u27 (best nutritional status). In contrast, the majority (64%) in the DC group were in the class \u27C\u27 (worst status). The compensated cirrhosis (CC) group showed that 90% of patients were malnourished, while 98% of all patients were malnourished in the DC group, predominantly class \u27C\u27. Most importantly, 14% of patients with chronic hepatitis C (CHC) also scored a \u27B\u27 on the SGA; which when compared to HC was statistically significant (p=0.005). As the groups progressed in their disease from CHC to DC, the transition in nutritional status from \u27A\u27 to \u27C\u27 between groups was statistically significant. CONCLUSION: Malnutrition occurs early in the course of HCV, and progresses relentlessly throughout the spectrum of HCVdisease

Application of algal nanotechnology for leather wastewater treatment and heavy metal removal efficiency

Wastewater from tanneries may ruin agricultural fields by polluting them with trace metals. The synthesis of nanoparticles (NPs) from algal sources and their application could help in decreasing hazardous materials, for environmental safety. The potential of zinc oxide nanoparticles made from Oedogonium sp. was evaluated for removal of heavy metals from leather industrial wastewater. Synthesized algal nanoparticles (0 (control), 0.1, 0.5, and 1 mg) were applied to treat wastewater by using different concentrations of leather industrial effluents (0%, 5%, 10%, 15%, and 100%) for 15, 30, and 45 d. The wastewater collected was dark brown to black in color with very high pH (8.21), EC (23.08 μs/cm), and TDS, (11.54 mg/L), while the chloride content was 6750 mg/L. The values of biological oxygen demand (BOD) and chemical oxygen demand (COD) ranged between 420 mg/L and 1123 mg/L in the current study. Prior to the application of nanoparticles, Cr (310.1), Cd (210.5), and Pb (75.5 mg/L) contents were higher in the leather effluents. The removal efficiency of TDS, chlorides, Cr, Cd, and Pb was improved by 46.5%, 43.5%, 54%, 57.6%, and 59.3%, respectively, following treatment with 1 mg of nanoparticles after 45 d. Our results suggested that the green synthesis of ZnO nanoparticles is a useful and ecofriendly biotechnological tool for treating tannery effluents, before they are discharged into water bodies, thus making the soil environment clean.Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia | Ref. PNURSP2022R7

SMART-KG: Hybrid Shipping for SPARQL Querying on the Web

While Linked Data (LD) provides standards for publishing (RDF) and (SPARQL) querying Knowledge Graphs (KGs) on the Web, serving, accessing and processing such open, decentralized KGs is often practically impossible, as query timeouts on publicly available SPARQL endpoints show. Alternative solutions such as Triple Pattern Fragments (TPF) attempt to tackle the problem of availability by pushing query processing workload to the client side, but suffer from unnecessary transfer of irrelevant data on complex queries with large intermediate results. In this paper we present smart-KG, a novel approach to share the load between servers and clients, while significantly reducing data transfer volume, by combining TPF with shipping compressed KG partitions. Our evaluations show that smart-KG outperforms state-of-the-art client-side solutions and increases server-side availability towards more cost-effective and balanced hosting of open and decentralized KGs

Knowledge, perceptions and myths regarding infertility among selected adult population in Pakistan: a cross-sectional study

<p>Abstract</p> <p>Background</p> <p>The reported prevalence of infertility in Pakistan is approximately 22% with 4% primary and 18% secondary infertility. Infertility is not only a medical but also a social problem in our society as cultural customs and perceived religious dictums may equate infertility with failure on a personal, interpersonal, or social level. It is imperative that people have adequate knowledge about infertility so couples can seek timely medical care and misconceptions can be rectified.</p> <p>We aim to assess the knowledge, perception and myths regarding infertility and suggest ways to improve it.</p> <p>Methods</p> <p>A cross-sectional survey was carried out by interviewing a sample of 447 adults who were accompanying the patients at two tertiary care hospitals in Karachi, Pakistan. They were interviewed one-on-one with the help of a pretested questionnaire drafted by the team after a thorough literature review and in consultation with infertility specialists.</p> <p>Results</p> <p>The correct knowledge of infertility was found to be limited amongst the participants. Only 25% correctly identified when infertility is pathological and only 46% knew about the fertile period in women's cycle. People are misinformed that use of IUCD (53%) and OCPs (61%) may cause infertility. Beliefs in evil forces and supernatural powers as a cause of infertility are still prevalent especially amongst people with lower level of education. Seeking alternative treatment for infertility remains a popular option for 28% of the participant as a primary preference and 75% as a secondary preference. IVF remains an unfamiliar (78%) and an unacceptable option (55%).</p> <p>Conclusions</p> <p>Knowledge about infertility is limited in the population and a lot of misconceptions and myths are prevalent in the society. Alternative medicine is a popular option for seeking infertility treatment. The cultural and religious perspective about assisted reproductive technologies is unclear, which has resulted in its reduced acceptability.</p

Clinical practice guidelines on the management of variceal bleeding

Gastroesophageal variceal bleeding occurs in 30 - 50% of patients of liver cirrhosis with portal hypertension, with 20-70% mortality in one year. Therefore, it is essential to screen these patients for varices and prevent first episode of bleeding by treating them with β-blockers or endoscopic variceal band ligation. Ideally, the patients with variceal bleeding should be treated in a unit where the personnel are familiar with the management of such patients and where routine therapeutic interventions can be undertaken. Proper management of such patients include: initial assessment, resuscitation, blood volume replacement, vasoactive agents, prevention of associated complications such as bacterial infections, hepatic encephalopathy, coagulopathy and thrombocytopenia, and specific therapy. Rebleeding occurs in about 60% patients within 2 years of their recovery from first variceal bleeding episode, with 33% mortality. Therefore, it is mandatory that all such patients must be started on combination of β-blockers and band ligation to prevent recurrence of bleeding. Patients who required shunt surgery/TIPSS to control the acute episode do not require further preventive measures. These clinical practice guidelines (CPGs) have been jointly developed by Pakistan Society of Hepatology (PSH) and Pakistan Society of Study of Liver Diseases (PSSLD)