V-Mail Written by Robert G. Harris to the Bryant College Service Club Dated June 5, 1943

[Transcription begins] Cpl. Robt. Harris 31119022 3406 Ord. MM Co. (Q) APO # 758, c/o Postmaster, N. Y. June 5, 1943 BRYANT SERVICE CLUB c/o BRYANT COLLEGE YOUNG & ORCHARD STS. PROVIDENCE, RHODE ISLAND U. S. A. Dear Bryant Service Club: It was a very pleasant surprise for me to receive a letter from my old Alma Mater. I think the idea of you kids back home keeping in touch with the old grads. is a swell jesture [sic]. Things like that make a fellow over here realize that he as [sic] a few friends in the world after all. Being away from home and in with a group of fellows you never new [sic], gives a soldier the impression he is almost alone in the world. Keep up your good work and let me in the latest news more often if possible. However, I realize that you must have a very difficult time trying to contact all of the boys. I am situated in North Africa, the exact spot can’t be mentioned because of the censor. This is a land of sun, sand and palm trees but mostly sun and sand. It is indeed [sic] a very educational part of the world, but as for myself they can give it back to the Arabs. Speaking of Arabs, there is a subject that [I] could write a book about but I’m afried [sic] it would not be published. I can say though that the movies builds you up for a big let-down, when it shows you some scenes of the country. There is one thing that interests me about these natives, and that is the work that they turn out by hand. They are still using methods that have been in practise [sic] for generation after generation, but the results obtained are wonderful. The difficulty is that a person needs a fortune to buy any of the things that they make. The chief mode of transportation is the burro and the less fortunates walk. It strikes me funny to see them walking down the street with their shoes in their hands. Personally I don’t get the point. Have you any ideas? Perhaps you would like to know my duties as a soldier. Well there isn’t much to write about on that subject. Every Company has an Orderly room in which the administrative work is done, and that is where I work. Being an accountant, they thought I would make a good clerk. Any one who has worked in civilian life as a clerk or accoutant [sic] I’M sure would find the Army administration interesting and amuseing [sic]. That seems to give you a very brief idea of some of the points as seen from a man on overseas duty. If anyone in school would like a little advise [sic] on planning for entrance into the service, I would suggest that they try and get into the Air Corps, either as a flyer or ground man. The Air Corps needs plenty of men for administration and is about the best branch of service in my estimation. Good luck to you in your Bryant Service Club and as I have written before write me a word whenever you can. I was in the class of ’38, and any new [sic] of the boys that were in that class and are now in the army would be of great interest to me. Write and let me know about them. May we all be celebrating a complete victory very soon, Sincerely, Robert G. Harris [Transcription ends

A 10-year Study of Factors Associated with Alcohol Treatment Use and Non-use in a U.S. Population Sample

Background This study seeks to identify changes in perceived barriers to alcohol treatment and predictors of treatment use between 1991–92 and 2001–02, to potentially help understand reported reductions in treatment use at this time. Social, economic, and health trends during these 10 years provide a context for the study. Methods Subjects were Whites, Blacks, and Hispanics. The data were from the National Longitudinal Alcohol Epidemiologic Survey (NLAES) and the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). We conducted two analyses that compared the surveys on: 1) perceived treatment barriers for subjects who thought they should get help for their drinking, and 2) variables predicting past-year treatment use in an alcohol use disorder subsample using a multi-group multivariate regression model. Results In the first analysis, those barriers that reflected negative beliefs and fears about seeking treatment as well as perceptions about the lack of need for treatment were more prevalent in 2001–02. The second analysis showed that survey year moderated the relationship between public insurance coverage and treatment use. This relationship was not statistically significant in 1991–92 but was significant and positive in 2001–02, although the effect of this change on treatment use was small. Conclusions Use of alcohol treatment in the U.S. may be affected by a number of factors, such as trends in public knowledge about treatment, social pressures to reduce drinking, and changes in the public financing of treatment

THE ROLE OF SWITCHING COSTS IN ANTITRUST ANALYSIS: A COMPARISON OF MICROSOFT AND GOOGLE

Recently there has been a chorus of competition complaints asserting that Google\u27s conduct and position today is parallel to Microsoft\u27s position in the “Microsoft case,” the antitrust case brought by the Department of Justice in 1998. Any monopolization case against Google Search would have to be very different from the Microsoft browser case, because the cost for a user switching from Google Search is much lower than was the cost in the 1990s (or today) of switching away from the Microsoft operating system. It would likewise need to be different because Google has not attempted to manipulate the cost of a user switching away from Google Search, at least not to a significant degree. Low switching costs should and likely will have important implications for antitrust analysis of Google

Inclusive Scholarship: Developing Black Studies in the United States

Brings together four reports commissioned between 1982 and 2000 that examine the history of African American Studies, its impact, and its institutionalization. Reviews Ford's grantmaking to African American Studies programs from 1982 to 2007

Optimizing astrophotonic spatial reformatters using simulated on-sky performance

One of the most useful techniques in astronomical instrumentation is image slicing. It enables a spectrograph to have a more compact angular slit, whilst retaining throughput and increasing resolving power. Astrophotonic components like the photonic lanterns and photonic reformatters can be used to replace bulk optics used so far. This study investigates the performance of such devices using end-to-end simulations to approximate realistic on-sky conditions. It investigates existing components, tries to optimize their performance and aims to understand better how best to design instruments to maximize their performance. This work complements the recent work in the field and provides an estimation for the performance of the new components.Comment: Conference proceedings in SPIE 2018 Austin Texa

DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity.

An individual malignant tumor is composed of a heterogeneous collection of single cells with distinct molecular and phenotypic features, a phenomenon termed intratumoral heterogeneity. Intratumoral heterogeneity poses challenges for cancer treatment, motivating the need for combination therapies. Single-cell technologies are now available to guide effective drug combinations by accounting for intratumoral heterogeneity through the analysis of the signaling perturbations of an individual tumor sample screened by a drug panel. In particular, Mass Cytometry Time-of-Flight (CyTOF) is a high-throughput single-cell technology that enables the simultaneous measurements of multiple ([Formula: see text]40) intracellular and surface markers at the level of single cells for hundreds of thousands of cells in a sample. We developed a computational framework, entitled Drug Nested Effects Models (DRUG-NEM), to analyze CyTOF single-drug perturbation data for the purpose of individualizing drug combinations. DRUG-NEM optimizes drug combinations by choosing the minimum number of drugs that produce the maximal desired intracellular effects based on nested effects modeling. We demonstrate the performance of DRUG-NEM using single-cell drug perturbation data from tumor cell lines and primary leukemia samples