Effect of a selective IKK2 inhibitor on markers of inflammation both in vitro and in vivo

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Using the consensus development conference method in healthcare research

Consensus methods are increasingly being used in healthcare research, particularly for formulating policy and strategic directions. This paper by Elizabeth Halcomb, Patricia Davidson and Laura Hardaker discusses the issues central to the planning and conduct of the consensus development conference, and offers practical recommendations to researchers intending to use this approach

Making sense of uncertainty: why uncertainty is part of science

Scientific uncertainty is prominent in research that has big implications for our society: could the Arctic be ice-free in summer by 2080? Will a new cancer drug be worth its side effects? Is this strain of ‘flu going to be a dangerous epidemic? Uncertainty is normal currency in scientific research. Research goes on because we don’t know everything. Researchers then have to estimate how much of the picture is known and how confident we can all be that their findings tell us what’s happening or what’s going to happen. This is uncertainty

Anatomic pathology

The purpose of this study was to describe the demographic and employment characteristics of Australian occupational therapists working in youth mental health and explore the relationship between these characteristics and the occupational therapist's role. Sixty-three occupational therapists completed a postal survey during 2006-2007. Numerical data were analyzed using descriptive statistics and qualitative data were analyzed using thematic analysis. The majority (86%) of participants were female, with a mean age of 31.8 years. Over half of the participants were employed as occupational therapists (60%). While most participants reported less than five years’ experience working with young people (92.5%), thirty-nine participants (61.9%) expressed optimism about the future of occupational therapy in youth mental health. Factors such as funding, staff retention, support, training, and attitudes surrounding professional roles were identified as barriers to role expansion. Occupational therapists work in a range of mental health settings that provide services to young people. Data suggest that occupational therapists are optimistic about working in this field; however, they have limited resources to guide their practice and assist in developing and maintaining professional identity. Study data reveal a need to overcome the funding and professional barriers that currently affect the role of the occupational therapist in youth mental health. Expansion of the occupational therapist's role in youth mental health would be advantageous to both the profession of occupational therapy and the multidisciplinary team

The role of the occupational therapist in adolescent mental health : a critical review of the literature

There are substantial bodies of literature focusing on mental health and the mental health of young people. There is also a growing body of knowledge relating to the professional role of the occupational therapists in mental health. However, there is a marked gap that brings these areas together. Adolescence is a time of heightened stress, with as many as one in four young people experiencing a mental health problem; appropriate care is required to reduce the impact of mental illness on their transition into adulthood and subsequent adult life. Whilst the effectiveness of the multidisciplinary team in providing interventions has been well demonstrated in this client group, the roles and impact of the individual health professionals are less well understood. A review of the literature was conducted to better understand the current and potential role for occupational therapists working with young people with mental health issues