43 research outputs found
LANTHANIDE-DOPED UPCONVERSION NANOCRYSTALS: SYNTHESIS, OPTICAL TUNING AND BIOAPPLICATIONS
Ph.DDOCTOR OF PHILOSOPH
Ladder-like energy-relaying exciplex enables 100% internal quantum efficiency of white TADF-based diodes in a single emissive layer.
Development of white organic light-emitting diodes based on purely thermally activated delayed fluorescence with a single-emissive-layer configuration has been a formidable challenge. Here, we report the rational design of a donor-acceptor energy-relaying exciplex and its utility in fabricating single-emissive-layer, thermally activated delayed fluorescence-based white organic light-emitting diodes that exhibit 100% internal quantum efficiency, 108.2 lm W-1 power efficiency, and 32.7% external quantum efficiency. This strategy enables thin-film fabrication of an 8 cm × 8 cm thermally activated delayed fluorescence white organic light-emitting diodes (10 inch2) prototype with 82.7 lm W-1 power efficiency and 25.0% external quantum efficiency. Introduction of a phosphine oxide-based acceptor with a steric group to the exciplex limits donor-acceptor triplet coupling, providing dual levels of high-lying and low-lying triplet energy. Transient spectroscopic characterizations confirm that a ladder-like energy relaying occurs from the high-lying triplet level of the exciplex to a blue emitter, then to the low-lying triplet level of the phosphine oxide acceptor, and ultimately to the yellow emitter. Our results demonstrate the broad applicability of energy relaying in multicomponent systems for exciton harvesting, providing opportunities for the development of third-generation white organic light-emitting diode light sources
Prompt-enhanced Hierarchical Transformer Elevating Cardiopulmonary Resuscitation Instruction via Temporal Action Segmentation
The vast majority of people who suffer unexpected cardiac arrest are
performed cardiopulmonary resuscitation (CPR) by passersby in a desperate
attempt to restore life, but endeavors turn out to be fruitless on account of
disqualification. Fortunately, many pieces of research manifest that
disciplined training will help to elevate the success rate of resuscitation,
which constantly desires a seamless combination of novel techniques to yield
further advancement. To this end, we collect a custom CPR video dataset in
which trainees make efforts to behave resuscitation on mannequins independently
in adherence to approved guidelines, thereby devising an auxiliary toolbox to
assist supervision and rectification of intermediate potential issues via
modern deep learning methodologies. Our research empirically views this problem
as a temporal action segmentation (TAS) task in computer vision, which aims to
segment an untrimmed video at a frame-wise level. Here, we propose a
Prompt-enhanced hierarchical Transformer (PhiTrans) that integrates three
indispensable modules, including a textual prompt-based Video Features
Extractor (VFE), a transformer-based Action Segmentation Executor (ASE), and a
regression-based Prediction Refinement Calibrator (PRC). The backbone of the
model preferentially derives from applications in three approved public
datasets (GTEA, 50Salads, and Breakfast) collected for TAS tasks, which
accounts for the excavation of the segmentation pipeline on the CPR dataset. In
general, we unprecedentedly probe into a feasible pipeline that genuinely
elevates the CPR instruction qualification via action segmentation in
conjunction with cutting-edge deep learning techniques. Associated experiments
advocate our implementation with multiple metrics surpassing 91.0%.Comment: Transformer for Cardiopulmonary Resuscitatio
Photon upconversion through triplet exciton-mediated energy relay.
Exploration of upconversion luminescence from lanthanide emitters through energy migration has profound implications for fundamental research and technology development. However, energy migration-mediated upconversion requires stringent experimental conditions, such as high power excitation and special migratory ions in the host lattice, imposing selection constraints on lanthanide emitters. Here we demonstrate photon upconversion of diverse lanthanide emitters by harnessing triplet exciton-mediated energy relay. Compared with gadolinium-based systems, this energy relay is less dependent on excitation power and enhances the emission intensity of Tb3+ by 158-fold. Mechanistic investigations reveal that emission enhancement is attributable to strong coupling between lanthanides and surface molecules, which enables fast triplet generation (<100 ps) and subsequent near-unity triplet transfer efficiency from surface ligands to lanthanides. Moreover, the energy relay approach supports long-distance energy transfer and allows upconversion modulation in microstructures. These findings enhance fundamental understanding of energy transfer at molecule-nanoparticle interfaces and open exciting avenues for developing hybrid, high-performance optical materials
Object Detection for Caries or Pit and Fissure Sealing Requirement in Children's First Permanent Molars
Dental caries is one of the most common oral diseases that, if left
untreated, can lead to a variety of oral problems. It mainly occurs inside the
pits and fissures on the occlusal/buccal/palatal surfaces of molars and
children are a high-risk group for pit and fissure caries in permanent molars.
Pit and fissure sealing is one of the most effective methods that is widely
used in prevention of pit and fissure caries. However, current detection of
pits and fissures or caries depends primarily on the experienced dentists,
which ordinary parents do not have, and children may miss the remedial
treatment without timely detection. To address this issue, we present a method
to autodetect caries and pit and fissure sealing requirements using oral photos
taken by smartphones. We use the YOLOv5 and YOLOX models and adopt a tiling
strategy to reduce information loss during image pre-processing. The best
result for YOLOXs model with tiling strategy is 72.3 mAP.5, while the best
result without tiling strategy is 71.2. YOLOv5s6 model with/without tiling
attains 70.9/67.9 mAP.5, respectively. We deploy the pre-trained network to
mobile devices as a WeChat applet, allowing in-home detection by parents or
children guardian
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Photon upconversion through triplet exciton-mediated energy relay
Funder: Innovation programme under the Marie Skłodowska-Curie grant agreement No 797619Funder: China Scholarship Council (CSC); doi: https://doi.org/10.13039/501100004543Funder: RCUK | Engineering and Physical Sciences Research Council (EPSRC); doi: https://doi.org/10.13039/501100000266Abstract: Exploration of upconversion luminescence from lanthanide emitters through energy migration has profound implications for fundamental research and technology development. However, energy migration-mediated upconversion requires stringent experimental conditions, such as high power excitation and special migratory ions in the host lattice, imposing selection constraints on lanthanide emitters. Here we demonstrate photon upconversion of diverse lanthanide emitters by harnessing triplet exciton-mediated energy relay. Compared with gadolinium-based systems, this energy relay is less dependent on excitation power and enhances the emission intensity of Tb3+ by 158-fold. Mechanistic investigations reveal that emission enhancement is attributable to strong coupling between lanthanides and surface molecules, which enables fast triplet generation (<100 ps) and subsequent near-unity triplet transfer efficiency from surface ligands to lanthanides. Moreover, the energy relay approach supports long-distance energy transfer and allows upconversion modulation in microstructures. These findings enhance fundamental understanding of energy transfer at molecule-nanoparticle interfaces and open exciting avenues for developing hybrid, high-performance optical materials
Intracellular Adenosine Triphosphate Deprivation through Lanthanide-Doped Nanoparticles
10.1021/jacs.5b00981Journal of the American Chemical Society137206550-655
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Research data supporting "Photon upconversion through triplet exciton-mediated energy relay"
The data sets stored here accompany the related research article, showing details of spectroscopic investigations. The opj. file contains spectroscopic data for four figures in manuscript. The file can be opened by Origin. Figure 1 contains upconversion emission spectra of NaYF4@NaYbF4:Tm@NaYF4:X(X=Tb3+ or Eu3+) in presence and absence of surface molecules. Figure 2a and 2b are plotted by Tb emission intensity as a function of ligand content and Tb content, respectively. Figure 2c is upconversion emission spectral of CPPOA-coated nanoparticles under different excitation power. Figure 2f is comparative upconversion emission spectra of CPPOA-modified NaYF4@NaYbF4:Tm (1 mol%)@NaYF4:Tb (red) and NaYbF4:Tm (1 mol%)@NaYF4:Tb (black) nanocrystals. Figure 3 contains transient absorption spectra and kinetics analysis of samples. Figure 4 contains upconversion spectra of CPPOA-coated microparticles. The txt file contains the code for Monte Carlo simulatio
Physical, Mechanical, Morphological, and Barrier Properties of Elephant Foot Yam Starch, Whey Protein Concentrate and psyllium
High-Efficiency in Vitro and in Vivo Detection of Zn2+ by Dye-Assembled Upconversion Nanoparticles
Development of highly sensitive and selective sensing systems of divalent zinc ion (Zn2+) in organisms has been a growing interest in the past decades owing to its pivotal role in cellular metabolism, apoptosis, and neurotransmission. Herein, we report the rational design and synthesis of a Zn2+ fluorescent-based probe by assembling lanthanide-doped upconversion nanoparticles (UCNPs) with chromophores. Specifically, upconversion luminescence (UCL) can be effectively quenched by the chromophores on the surface of nanoparticles via a fluorescence resonant energy transfer (FRET) process and subsequently recovered upon the addition of Zn2+, thus allowing for quantitative monitoring of Zn2+. Importantly, the sensing system enables detection of Zn2+ in real biological samples. We demonstrate that this chromophoreUCNP nanosystem is capable of implementing an efficient in vitro and in vivo detection of Zn2+ in mouse brain slice with Alzheimers disease and zebrafish, respectively.11118sciescopu