3,900 research outputs found
Electroweak Symmetry Breaking by Strong Dynamics and the Collider Phenomenology
We discuss the possible signatures in the electroweak symmetry breaking
sector by new strong dynamics at future hadron colliders such as the Tevatron
upgrade, the LHC and VLHC, and linear colliders. Examples include a
heavy Higgs-like scalar resonance, a heavy Technicolor-like vector resonance
and pseudo-Goldstone states, non-resonance signatures via enhanced gauge-boson
scattering and fermion compositeness.Comment: Summary report of the Strong Electroweak Symmetry Breaking Working
Group at 2001 Snowmass Summer Studie
Modeling Mg II h, k and Triplet Lines at Solar Flare Ribbons
Observations from the \textit{Interface Region Imaging Spectrograph}
(\textsl{IRIS}) often reveal significantly broadened and non-reversed profiles
of the Mg II h, k and triplet lines at flare ribbons. To understand the
formation of these optically thick Mg II lines, we perform plane parallel
radiative hydrodynamics modeling with the RADYN code, and then recalculate the
Mg II line profiles from RADYN atmosphere snapshots using the radiative
transfer code RH. We find that the current RH code significantly underestimates
the Mg II h \& k Stark widths. By implementing semi-classical perturbation
approximation results of quadratic Stark broadening from the STARK-B database
in the RH code, the Stark broadenings are found to be one order of magnitude
larger than those calculated from the current RH code. However, the improved
Stark widths are still too small, and another factor of 30 has to be multiplied
to reproduce the significantly broadened lines and adjacent continuum seen in
observations. Non-thermal electrons, magnetic fields, three-dimensional effects
or electron density effect may account for this factor. Without modifying the
RADYN atmosphere, we have also reproduced non-reversed Mg II h \& k profiles,
which appear when the electron beam energy flux is decreasing. These profiles
are formed at an electron density of
and a temperature of K, where the source function slightly
deviates from the Planck function. Our investigation also demonstrates that at
flare ribbons the triplet lines are formed in the upper chromosphere, close to
the formation heights of the h \& k lines
The Stability of Double White Dwarf Binaries Undergoing Direct Impact Accretion
We present numerical simulations of dynamically unstable mass transfer in a
double white dwarf binary with initial mass ratio, q = 0.4. The binary
components are approximated as polytropes of index n = 3/2 and the initially
synchronously rotating, semi-detached equilibrium binary is evolved
hydrodynamically with the gravitational potential being computed through the
solution of Poisson's equation. Upon initiating deep contact in our baseline
simulation, the mass transfer rate grows by more than an order of magnitude
over approximately ten orbits, as would be expected for dynamically unstable
mass transfer. However, the mass transfer rate then reaches a peak value, the
binary expands and the mass transfer event subsides. The binary must therefore
have crossed the critical mass ratio for stability against dynamical mass
transfer. Despite the initial loss of orbital angular momentum into the spin of
the accreting star, we find that the accretor's spin saturates and angular
momentum is returned to the orbit more efficiently than has been previously
suspected for binaries in the direct impact accretion mode. To explore this
surprising result, we directly measure the critical mass ratio for stability by
imposing artificial angular momentum loss at various rates to drive the binary
to an equilibrium mass transfer rate. For one of these driven evolutions, we
attain equilibrium mass transfer and deduce that effectively q_crit has evolved
to approximately 2/3. Despite the absence of a fully developed disk, tidal
interactions appear effective in returning excess spin angular momentum to the
orbit.Comment: 27 pages, 6 figures. Please see
http://www.phys.lsu.edu/faculty/tohline/astroph/mftd07/ for animations and
full resolution figures. Accepted for publication in the Astrophysical
Journa
Comparison of [11C]TZ1964B and [18F]MNI659 for PET imaging brain PDE10A in nonhuman primates
Phosphodiesterase 10A (PDE10A) inhibitors show therapeutic effects for diseases with striatal pathology. PET radiotracers have been developed to quantify in vivo PDE10A levels and target engagement for therapeutic interventions. The aim of this study was to compare two potent and selective PDE10A radiotracers, [(11)C]TZ1964B and [(18)F]MNI659 in the nonhuman primate (NHP) brain. Double scans in the same cynomolgus monkey on the same day were performed after injection of [(11)C]TZ1964B and [(18)F]MNI659. Specific uptake was determined in two ways: nondisplaceable binding potential (BP(ND)) was calculated using cerebellum as the reference region and the PDEâ10A enriched striatum as the target region of interest (ROI); the area under the timeâactivity curve (AUC) for the striatum to cerebellum ratio was also calculated. Highâperformance liquid chromatography (HPLC) analysis of solventâextracted NHP plasma identified the percentage of intact tracer versus radiolabeled metabolites samples post injection of each radiotracer. Both radiotracers showed high specific accumulation in NHP striatum. [(11)C]TZ1964B has higher striatal retention and lower specific striatal uptake than [(18)F]MNI659. The BP(ND) estimates of [(11)C]TZ1964B were 3.72 by Logan Reference model (LoganREF) and 4.39 by simplified reference tissue model (SRTM); the BP(ND) estimates for [(18)F]MNI659 were 5.08 (LoganREF) and 5.33 (SRTM). AUC ratios were 5.87 for [(11)C]TZ1964B and 7.60 for [(18)F]MNI659. Based on BP(ND) values in NHP striatum, coefficients of variation were ~10% for [(11)C]TZ1964B and ~30% for [(18)F]MNI659. Moreover, the metabolism study showed the percentage of parent compounds were ~70% for [(11)C]TZ1964B and ~50% for [(18)F]MNI659 60 min post injection. These data indicate that either [(11)C]TZ1964B or [(18)F]MNI659 could serve as suitable PDE10A PET radiotracers with distinguishing features for particular clinical application
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