Spin-dependent empirical formula for the lowest excitation energies of the natural parity states in even-even nuclei

We present an empirical expression which holds for the lowest excitation energy of the natural parity states in even-even nuclei throughout the entire periodic table. This formula contains spin-dependent factors so that it is applied to different multipole states with the same model parameters in contrast to the recently proposed empirical expression where the model parameters had to be fitted for each multipole separately.Comment: 9 pages, 5 figure

Why does the recently proposed simple empirical formula for the lowest excitation energies work so well?

It has recently been shown that a simple empirical formula, in terms of the mass number and the valence nucleon numbers, is able to describe the main trends of the lowest excitation energies of the natural parity even multipole states up to $10^+$ in even-even nuclei throughout the entire periodic table. In an effort to understand why such a simple formula is so capable, we investigate the possibility of associating each term of the empirical formula with the specific part of the measured excitation energy graph.Comment: 9 pages, 3 figure

Cellular Sheaves And Cosheaves For Distributed Topological Data Analysis

This dissertation proposes cellular sheaf theory as a method for decomposing data analysis problems. We present novel approaches to problems in pursuit and evasion games and topological data analysis, where cellular sheaves and cosheaves are used to extract global information from data distributed with respect to time, boolean constraints, spatial location, and density. The main contribution of this dissertation lies in the enrichment of a fundamental tool in topological data analysis, called persistent homology, through cellular sheaf theory. We present a distributed computation mechanism of persistent homology using cellular cosheaves. Our construction is an extension of the generalized Mayer-Vietoris principle to filtered spaces obtained via a sequence of spectral sequences. We discuss a general framework in which the distribution scheme can be adapted according to a user-specific property of interest. The resulting persistent homology reflects properties of the topological features, allowing the user to perform refined data analysis. Finally, we apply our construction to perform a multi-scale analysis to detect features of varying sizes that are overlooked by standard persistent homology

Radiation-induced genomic instability and LINE-1 hypomethylation in radiographers

Genomic instability is an important factor in cancer induced by ionizing radiation. Global DNA hypomethylation has been recently proposed as a potential biomarker for cancer risk through genomic instability. However the association between low-dose ionizing radiation exposure and DNA methylation changes is unclear. This study aimed to understand the epigenetic mechanisms associated with low-level radiation exposure and radiation-induced genomic instability (RIGI) among industrial radiographers

Epigenetic biomarkers for Alzheimer’s disease using a transgenic porcine model

Alzheimer’s disease (AD) is the most common cause of dementia, accounting for approximately 60~70% of dementia cases. AD afflicts more than 35.6 million individuals worldwide and is expected to increase to 65.7 million by 2030 and 115.4 million by 2050 1; AD is a serious public health problem that is causing increased health care costs worldwide. Typically, AD is a relentlessly progressive disorder that initially manifests as severe loss of memory, particularly episodic memory.2 The disorder is not curable at present, and the mechanisms driving development of AD are not fully understood. Therefore, there is an urgent need to develop and characterize relevant AD transgenic animal models to facilitate translational research and preclinical testing of therapeutic agents.3 Furthermore, it is imperative to discover the underlying mechanisms that exacerbate AD, which hinder mitigation efforts to reduce the health burden of this disease

The Meaning of Zenocrate in Tamburlaine, Parts I and II

Christopher Marlowe\u27s Tamburlaine the Great, Parts I and II are built around a single towering superman, Tamburlaine, just as three of his other plays are built around strong protagonists: Barabas, Guise, and Faustus. Most critics have acknowledged that the protagonist, Tamburlaine, is the only unifying factor, or the be-all and end-all of the action. From the beginning to the end, both plays unfold while centering exclusively on the protagonist, and the protagonist powerfully dominates both plays. The other characters of the play are often referred to merely as Tamburlaine\u27s “puppets and serve as his foils. Furthermore, the subsidiary figures, whether miserable or not, are enormously influenced and wholly swayed by Tamburlaine\u27s movements. In turn, Tamburlaine is generous and fair to his loyal friends, while savagely bloody and cruel to his disobedient enemies. Throughout both plays, with the exception of the Soldan and Zenocrate, the other characters never change their attitudes toward Tamburlaine, and Tamburlaine also never changes his attitude toward them. Therefore, Irving Ribner has criticized that all the characters of the Tamburlaine plays are fixed and changeless, and there is no development, and when the play ends, they are no more or no less than they had been at the beginning. C. B. Kuriyama has similarly remarked that Tamburlaine may be fairly described as a play of extremes that tends to represent experience as a continuous oscillation between opposites, \u27 and that no character in these plays possesses strengths and weaknesses in roughly equal proportions. In view of these remarks, there is no middle ground \u27 in Tamburlaine\u27s world. But it is my opinion that there is one exceptional character in Tamburlaine\u27s world--the fair and divine Zenocrate. On the whole, then, Zenocrate seems to be timid and elusive, but her presence in both plays is crucial to understanding Tamburlaine and his world. Apparently, because of Zenocrate\u27s absence, Part· II seems to lose its balance as the play goes on, while Part I remains balanced because of her presence. My aim in this thesis is to study the meaning of Zenocrate in both Tambu rlaine plays. The main focus of this work will be on the relationship of Tamburlaine and Zenocrate: Zenocrate\u27s meaning as conceived by Tamburlaine, her influence (particularly her moderating influence) over Tamburlaine and his reaction to her influence, the meaning of Zenocrate\u27s death and its impact on Tamburlaine, and the outcome of the reciprocal conflicts of both figures