4 research outputs found

    The primary cancer morphology of fallopian tube

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    Introduction. Despite significant progress in the study of malignant tumors, the primary cancer of the fallopian tubes (PCFT) is not fully studied yet. According to different authors its incidence accounts from 0.14% to 1.8% of all female genital malignancies. The modern oncomorphology is in search of the criteria that will allow to verify the degree of biological malignancy and to predict the course of the disease with maximum objectivity. The study of molecular markers will allow to provide the adequate treatment of the patients with advanced processes and to improve the assessment of vulnerability to certain therapies

    The primary cancer morphology of fallopian tube

    Get PDF
    Introduction. Despite significant progress in the study of malignant tumors, the primary cancer of the fallopian tubes (PCFT) is not fully studied yet. According to different authors its incidence accounts from 0.14% to 1.8% of all female genital malignancies. The modern oncomorphology is in search of the criteria that will allow to verify the degree of biological malignancy and to predict the course of the disease with maximum objectivity. The study of molecular markers will allow to provide the adequate treatment of the patients with advanced processes and to improve the assessment of vulnerability to certain therapies

    Π’ΠΈΠΏΠ°Π΄ΠΎΠΊ синхронного Ρ€Π°ΠΊΡƒ ΠΌΠ°Ρ‚ΠΊΠΎΠ²ΠΎΡ— Ρ‚Ρ€ΡƒΠ±ΠΈ Ρ– СндомСтрія. ΠšΠ»Ρ–Π½Ρ–Ρ‡Π½Π΅ спостСрСТСння

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    Background. The problems of pre-operative cancer diagnosis of the fallopian tube are associated with a rare occurrence of this disease. More rarely, there is a combination of the fallopian tube cancer and other gynecological tumors. Clinical observation of the fallopian tube cancer and endometrial cancer in postmenopausal woman is presented, which demonstrates the difficulty of the pre-operative diagnostics of these pathologies combination.Case presentation. We described a case of uterine tube cancer in Ukrainian woman (77 years), which had been combined with adenocarcinoma of an endometrium.Conclusion. Primary fallopian tubes carcinoma is a rare disease with an insufficiently studied etiology. The clinical manifestations are not always present in full. Diagnosis in pre-operative period is very hard to establish. Only the qualitative morphological investigation allows establishing the primary lesion of the fallopian tube. Introducing immunohistochemical investigations in practice serves as additional methods for correct diseases diagnostic, which allow more fully characterizing the prognosis and suggesting appropriate treatment of the patients.Β ΠŸΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ Π΄ΠΎΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ диагностики Ρ€Π°ΠΊΠ° ΠΌΠ°Ρ‚ΠΎΡ‡Π½ΠΎΠΉ Ρ‚Ρ€ΡƒΠ±Ρ‹ связаны с Ρ€Π΅Π΄ΠΊΠΎΠΉ Π²ΡΡ‚Ρ€Π΅Ρ‡Π°Π΅ΠΌΠΎΡΡ‚ΡŒΡŽ Π΄Π°Π½Π½ΠΎΠ³ΠΎ заболСвания. Π•Ρ‰Π΅ Ρ€Π΅ΠΆΠ΅ ΠΎΡ‚ΠΌΠ΅Ρ‡Π°ΡŽΡ‚ сочСтаниС Ρ€Π°ΠΊΠ° ΠΌΠ°Ρ‚ΠΎΡ‡Π½ΠΎΠΉ Ρ‚Ρ€ΡƒΠ±Ρ‹ ΠΈ Π΄Ρ€ΡƒΠ³ΠΈΡ… гинСкологичСских ΠΎΠΏΡƒΡ…ΠΎΠ»Π΅ΠΉ. ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½ΠΎ клиничСскоС наблюдСниС Ρ€Π°ΠΊΠ° ΠΌΠ°Ρ‚ΠΎΡ‡Π½ΠΎΠΉ Ρ‚Ρ€ΡƒΠ±Ρ‹ ΠΈ Ρ€Π°ΠΊΠ° эндомСтрия Ρƒ ΠΆΠ΅Π½Ρ‰ΠΈΠ½Ρ‹ Π² постмСнопаузС, ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠ΅ дСмонстрируСт слоТности Π΄ΠΎΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ диагностики ΠΊΠΎΠΌΠ±ΠΈΠ½Π°Ρ†ΠΈΠΈ Π΄Π°Π½Π½Ρ‹Ρ… ΠΏΠ°Ρ‚ΠΎΠ»ΠΎΠ³ΠΈΠΉ.ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½ΠΈΠ΅ случая. Описали случай Ρ€Π°ΠΊΠ° ΠΌΠ°Ρ‚ΠΎΡ‡Π½ΠΎΠΉ Ρ‚Ρ€ΡƒΠ±Ρ‹ Ρƒ украинской ΠΆΠ΅Π½Ρ‰ΠΈΠ½Ρ‹ (77 Π»Π΅Ρ‚), ΠΊΠΎΡ‚ΠΎΡ€Ρ‹ΠΉ сочСтался с Π°Π΄Π΅Π½ΠΎΠΊΠ°Ρ€Ρ†ΠΈΠ½ΠΎΠΌΠΎΠΉ эндомСтрия.Π’Ρ‹Π²ΠΎΠ΄Ρ‹. ΠŸΠ΅Ρ€Π²ΠΈΡ‡Π½Ρ‹ΠΉ Ρ€Π°ΠΊ ΠΌΠ°Ρ‚ΠΎΡ‡Π½Ρ‹Ρ… Ρ‚Ρ€ΡƒΠ± – рСдкая патология с нСдостаточно ΠΈΠ·ΡƒΡ‡Π΅Π½Π½ΠΎΠΉ этиологиСй. ΠšΠ»ΠΈΠ½ΠΈΡ‡Π΅ΡΠΊΠΈΠ΅ проявлСния Π½Π΅ всСгда ΠΏΡ€ΠΈΡΡƒΡ‚ΡΡ‚Π²ΡƒΡŽΡ‚ Π² ΠΏΠΎΠ»Π½ΠΎΠΌ объСмС. Π”ΠΈΠ°Π³Π½ΠΎΠ· Π² ΠΏΡ€Π΅Π΄ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΌ ΠΏΠ΅Ρ€ΠΈΠΎΠ΄Π΅ ΡƒΡΡ‚Π°Π½Π°Π²Π»ΠΈΠ²Π°ΡŽΡ‚ Ρ€Π΅Π΄ΠΊΠΎ. Волько качСствСнноС морфологичСскоС исслСдованиС позволяСт ΡƒΡΡ‚Π°Π½ΠΎΠ²ΠΈΡ‚ΡŒ ΠΏΠ΅Ρ€Π²ΠΈΡ‡Π½ΠΎΡΡ‚ΡŒ пораТСния ΠΌΠ°Ρ‚ΠΎΡ‡Π½ΠΎΠΉ Ρ‚Ρ€ΡƒΠ±Ρ‹. Π˜ΠΌΠΌΡƒΠ½ΠΎΠ³ΠΈΡΡ‚ΠΎΡ…ΠΈΠΌΠΈΡ‡Π΅ΡΠΊΠΈΠ΅ исслСдования Π½Π° ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΠ΅ слуТат Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹ΠΌΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Π°ΠΌΠΈ для ΠΏΡ€Π°Π²ΠΈΠ»ΡŒΠ½ΠΎΠΉ диагностики Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡŽΡ‚ Π±ΠΎΠ»Π΅Π΅ ΠΏΠΎΠ»Π½ΠΎ ΠΎΡ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ΠΈΠ·ΠΎΠ²Π°Ρ‚ΡŒ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ· ΠΈ ΠΏΡ€Π΅Π΄Π»ΠΎΠΆΠΈΡ‚ΡŒ Π°Π΄Π΅ΠΊΠ²Π°Ρ‚Π½Ρ‹Π΅ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹ лСчСния ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ².Β ΠŸΡ€ΠΎΠ±Π»Π΅ΠΌΠΈ Π΄ΠΎΠΎΠΏΠ΅Ρ€Π°Ρ†Ρ–ΠΉΠ½ΠΎΡ— діагностики Ρ€Π°ΠΊΡƒ ΠΌΠ°Ρ‚ΠΊΠΎΠ²ΠΎΡ— Ρ‚Ρ€ΡƒΠ±ΠΈ пов’язані Π· Ρ€Ρ–Π΄ΠΊΡ–ΡΡ‚ΡŽ виникнСння Ρ†ΡŒΠΎΠ³ΠΎ Π·Π°Ρ…Π²ΠΎΡ€ΡŽΠ²Π°Π½Π½Ρ. Π©Π΅ Ρ€Ρ–Π΄ΡˆΠ΅ ΡΠΏΠΎΡΡ‚Π΅Ρ€Ρ–Π³Π°ΡŽΡ‚ΡŒ поєднання Ρ€Π°ΠΊΡƒ ΠΌΠ°Ρ‚ΠΊΠΎΠ²ΠΎΡ— Ρ‚Ρ€ΡƒΠ±ΠΈ Ρ‚Π° Ρ–Π½ΡˆΠΈΡ… Π³Ρ–Π½Π΅ΠΊΠΎΠ»ΠΎΠ³Ρ–Ρ‡Π½ΠΈΡ… ΠΏΡƒΡ…Π»ΠΈΠ½. НавСдСно ΠΊΠ»Ρ–Π½Ρ–Ρ‡Π½Π΅ спостСрСТСння Ρ€Π°ΠΊΡƒ ΠΌΠ°Ρ‚ΠΊΠΎΠ²ΠΎΡ— Ρ‚Ρ€ΡƒΠ±ΠΈ Ρ– Ρ€Π°ΠΊΡƒ СндомСтрія Ρƒ ΠΆΡ–Π½ΠΊΠΈ Π² постмСнопаузі, якС дСмонструє складності Π΄ΠΎΠΎΠΏΠ΅Ρ€Π°Ρ†Ρ–ΠΉΠ½ΠΎΡ— діагностики ΠΊΠΎΠΌΠ±Ρ–Π½Π°Ρ†Ρ–Ρ— Ρ†ΠΈΡ… ΠΏΠ°Ρ‚ΠΎΠ»ΠΎΠ³Ρ–ΠΉ.ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½Π½Ρ Π²ΠΈΠΏΠ°Π΄ΠΊΡƒ. Описали Π²ΠΈΠΏΠ°Π΄ΠΎΠΊ Ρ€Π°ΠΊΡƒ ΠΌΠ°Ρ‚ΠΊΠΎΠ²ΠΎΡ— Ρ‚Ρ€ΡƒΠ±ΠΈ Π² ΡƒΠΊΡ€Π°Ρ—Π½ΡΡŒΠΊΠΎΡ— ΠΆΡ–Π½ΠΊΠΈ (77 Ρ€ΠΎΠΊΡ–Π²), який поєднувався Π· Π°Π΄Π΅Π½ΠΎΠΊΠ°Ρ€Ρ†ΠΈΠ½ΠΎΠΌΠΎΡŽ СндомСтрія.Висновки. ΠŸΠ΅Ρ€Π²ΠΈΠ½Π½ΠΈΠΉ Ρ€Π°ΠΊ ΠΌΠ°Ρ‚ΠΊΠΎΠ²ΠΈΡ… Ρ‚Ρ€ΡƒΠ± Ρ” Ρ€Ρ–Π΄ΠΊΡ–ΡΠ½ΠΎΡŽ ΠΏΠ°Ρ‚ΠΎΠ»ΠΎΠ³Ρ–Ρ”ΡŽ Π· Π½Π΅Π΄ΠΎΡΡ‚Π°Ρ‚Π½ΡŒΠΎ Π²ΠΈΠ²Ρ‡Π΅Π½ΠΎΡŽ Π΅Ρ‚Ρ–ΠΎΠ»ΠΎΠ³Ρ–Ρ”ΡŽ. ΠšΠ»Ρ–Π½Ρ–Ρ‡Π½Ρ– прояви Π½Π΅ Π·Π°Π²ΠΆΠ΄ΠΈ наявні Π² ΠΏΠΎΠ²Π½ΠΎΠΌΡƒ обсязі. Π”Ρ–Π°Π³Π½ΠΎΠ· Ρƒ ΠΏΠ΅Ρ€Π΅Π΄ΠΎΠΏΠ΅Ρ€Π°Ρ†Ρ–ΠΉΠ½ΠΎΠΌΡƒ ΠΏΠ΅Ρ€Ρ–ΠΎΠ΄Ρ– Π²ΡΡ‚Π°Π½ΠΎΠ²Π»ΡŽΡŽΡ‚ΡŒ Ρ€Ρ–Π΄ΠΊΠΎ. Π’Ρ–Π»ΡŒΠΊΠΈ якіснС ΠΌΠΎΡ€Ρ„ΠΎΠ»ΠΎΠ³Ρ–Ρ‡Π½Π΅ дослідТСння Π΄Π°Ρ” ΠΌΠΎΠΆΠ»ΠΈΠ²Ρ–ΡΡ‚ΡŒ Π²ΠΈΠ·Π½Π°Ρ‡ΠΈΡ‚ΠΈ ΠΏΠ΅Ρ€Π²ΠΈΠ½Π½Ρ–ΡΡ‚ΡŒ ураТСння ΠΌΠ°Ρ‚ΠΊΠΎΠ²ΠΎΡ— Ρ‚Ρ€ΡƒΠ±ΠΈ. ВпровадТСння імуногістохімічних Π΄ΠΎΡΠ»Ρ–Π΄ΠΆΠ΅Π½ΡŒ Ρƒ ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΡƒ Ρ” Π΄ΠΎΠ΄Π°Ρ‚ΠΊΠΎΠ²ΠΈΠΌ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ для ΠΏΡ€Π°Π²ΠΈΠ»ΡŒΠ½ΠΎΡ— діагностики Π·Π°Ρ…Π²ΠΎΡ€ΡŽΠ²Π°Π½ΡŒ, які Π΄Π°ΡŽΡ‚ΡŒ Π·ΠΌΠΎΠ³Ρƒ Ρ‚ΠΎΡ‡Π½Ρ–ΡˆΠ΅ ΠΎΡ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ΠΈΠ·ΡƒΠ²Π°Ρ‚ΠΈ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ· Ρ– Π·Π°ΠΏΡ€ΠΎΠΏΠΎΠ½ΡƒΠ²Π°Ρ‚ΠΈ Π°Π΄Π΅ΠΊΠ²Π°Ρ‚Π½Ρ– ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈ лікування ΠΏΠ°Ρ†Ρ–Ρ”Π½Ρ‚Ρ–Π².

    The case of synchronous fallopian tube and endometrium cancer. Clinical observation

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    Abstract Background. The problems of pre-operative cancer diagnosis of the fallopian tube are associated with a rare occurrence of this disease. More rarely, there is a combination of the fallopian tube cancer and other gynecological tumors. Clinical observation of the fallopian tube cancer and endometrial cancer in postmenopausal woman is presented, which demonstrates the difficulty of the pre-operative diagnostics of these pathologies combination. Case presentation. We described a case of uterine tube cancer in Ukrainian woman (77 years), which had been combined with adenocarcinoma of an endometrium. Conclusion. Primary fallopian tubes carcinoma is a rare disease with an insufficiently studied etiology. The clinical manifestations are not always present in full. Diagnosis in pre-operative period is very hard to establish. Only the qualitative morphological investigation allows establishing the primary lesion of the fallopian tube. Introducing immunohistochemical investigations in practice serves as additional methods for correct diseases diagnostic, which allow more fully characterizing the prognosis and suggesting appropriate treatment of the patients
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