Barriers and Resources for Competitive Adaptive Rock Climbing

The purpose of this project was to (1) identify barriers to participation in competitive adaptive rock climbing for adults with a physical disability and (2) create and distribute virtual educational resources to meet identified barriers. The need for this project was highlighted by athlete and coach self-report of limited ability to engage in competitive adaptive rock climbing, also known as paraclimbing. The sample consisted of 108 adaptive athletes, adaptive rock-climbing coaches, staff members in rock climbing gyms, and volunteers at adaptive rock climbing events. Participants anonymously completed a ten-minute mixed methods virtual survey using Microsoft Forms. Statistical analyses suggest recurrent barriers to participation in competitive paraclimbing including lack of accessibility within the gym environment, limited financial and social resources, and confusion regarding the paraclimbing classification criteria and competition rulebook for national and world cup competitions. Thematic analysis of free response questions suggests additional barriers of poor disability etiquette from able-bodied staff and volunteers, a lack of “community” at the climbing gym, and limited diversity in the climbing community. Educational resources were created and published through a novel corporation created by the author, the Adaptive Climbing Alliance LLC. Resources were distributed virtually after being published on a freely accessible, community centered domain entitled Paraclimbing Info. Resources promote equity for paraclimbers and support the growing field of adaptive athletics.https://soar.usa.edu/otdcapstones-spring2022/1008/thumbnail.jp

A New Lease on Life: The Occupational Impact of Adaptive Skiing

This research study focuses on understanding the occupational impact of adaptive skiing on well-being and identity to promote lifelong occupational engagement, representation, and inclusion within current ski culture. A mixed-method research study utilized a 25-question online survey and an optional one-time virtual interview. 50 adaptive skiers and/or snowboarders participating in a winter adaptive program between 18-65 years old completed this study. This study found positive evidence supporting outcomes related to physical, emotional, spiritual, and social well-being and positive identity formation from adaptive skiing.https://soar.usa.edu/otdcapstonesspring2024/1021/thumbnail.jp

Exploring the Occupation of Adaptive Skateboarding

The occupation of adaptive skateboarding strives to bring inclusivity to skateboarding by means of adaptational strategies that support performance for individuals with varied abilities. The purpose of this capstone project is to explore the occupation of adaptive skateboarding to increase the occupational knowledge and to inform occupational therapy’s role. A mixed methods research study was conducted to explore the question: What are the supports and barriers for participation in adaptive skateboarding? Additional community-based capstone experiences occurred to support the comprehensive findings that consider the role of occupational therapy in promoting participation. Conclusions highlight the meaning of the occupation of adaptive skateboarding, the need for further scientific literature, and the need for roles of advocacy that reduce barriers to participation.https://soar.usa.edu/otdcapstonesspring2024/1047/thumbnail.jp

Detecting Masculinity: The Positive Masculine Qualities of Fictional Detectives.

Detective fiction highlights those qualities of masculinity that are most valuable to a contemporary culture. In mysteries a cultural context is more thoroughly revealed than in any other genre of literature. Through the crimes, an audience can understand not only the fears of a particular society but also the level of calumny that society assigns to a crime. As each generation has needed a particular set of qualities in its defense, so the detective has provided them. Through the detective's response to particular crimes, the reader can learn the delineation of forgivable and unforgivable acts. These detectives illustrate positive masculinity, proving that fiction has more uses than mere entertainment. In this paper, I trace four detectives, each from a different era. Sherlock Holmes lives to solve problems. His primary function is to solve a riddle. Lord Peter Wimsey takes on the moral question of why anyone should detect at all. His stories involve the difficulty of justifying putting oneself in the morally superior position of judge. The Mike Hammer stories treat the difficulty of dealing with criminals who use the law to protect themselves. They have perverted the protections of society, and Hammer must find a way to bring them to justice outside of the law. The Kate Martinelli stories focus more on the victims of crime than on the criminals. Martinelli discovers the motivations that draw a criminal toward a specific victim and explains what it is about certain victims that makes villains want to harm them. All of these detectives display the traditional traits of the Western male. They are hunters; they protect society as a whole. Yet each detective fulfills a certain cultural role that speaks to the specific problems of his or her era, proving that masculinity is a more fluid role than many have previously credited

Application of Occupation-Based Models to Edward of Edward Scissorhands: OA and EHP Models

This presentation examines the character Edward Scissorhands, a young adult with hand deformities and poor social skills, through the lens of the Ecological Human Performance (EHP) Model. We propose occupational therapy interventions based off of the EHP model. Through the use of establishing social skills training, as well as adapting and modifying Edward’s hands with tips and attachments, Edward’s life could be immensely improvedhttps://soar.usa.edu/casmfall2019/1007/thumbnail.jp

Anti-TNF-α antibody allows healing of joint damage in polyarthritic transgenic mice

Anti-tumor-necrosis-factor-α (TNF-α) monoclonal antibody was used to treat Tg197 transgenic mice, which constitutively produce human TNF-α (hTNF-α) and develop a progressive polyarthritic disease. Treatment of both young (7- or 8-week-old) and aged (27- or 28-week-old) mice commenced when at least two limbs showed signs of moderate to severe arthritis. The therapeutic efficacy of anti-TNF-α antibody was assessed using various pathological indicators of disease progression. The clinical severity of arthritis in Tg197 mice was significantly reduced after anti-TNF-α treatment in comparison with saline-treated mice and in comparison with baseline assessments in both young and aged mice. The treatment with anti-TNF-α prevented loss of body weight. Inflammatory pathways as reflected by elevated circulating hTNF-α and local expression of various proinflammatory mediators were all diminished by anti-TNF-α treatment, confirming a critical role of hTNF-α in this model of progressive polyarthritis. More importantly, the amelioration of the disease was associated with reversal of existing structural damage, including synovitis and periosteal bone erosions evident on histology. Repair of cartilage was age dependent: reversal of cartilage degradation after anti-TNF-α treatment was observed in young mice but not in aged mice

Capacity and Maximal Inspiratory Pressure in Healthy Adults

Introduction Diaphragmatic fatigue during maximal exercise causes decreased blood flow to exercising limbs. Inspiratory muscle strength training (IMST) may decrease diaphragm fatigue. Current studies use 50% of maximal inspiratory pressure (MIP) for IMST, but optimal dosing at higher intensities has not been well explored. Objective Investigate the impact of high intensity IMST on aerobic capacity and maximal inspiratory pressure in healthy adults. Methods This study was IRB approved by the university. All participants provided informed consent, and demographic information was collected. Results VO2 max did not change significantly in either intervention group after intervention period (p=0.143). Groups demonstrated significant improvement in MIP (p=0.011), but there was no significant difference between groups (p\u3c0.638). Conclusion VO2 max did not significantly change in the control or intervention groups. Post-intervention MIP measurements were significantly improved in both groups, but there was no significant difference between either group. High intensity IMST may not improve aerobic capacity in young, healthy adults after an 8-week intervention period. Clinical Relevance Maintaining diaphragmatic strength with IMST may help minimize respiratory fatigue and be useful for healthy adults with injuries limiting their mobility. Further research is needed to evaluate optimal IMST intensity for maximal benefit as 80% may be too intense

Assessment of Inactivating Stop Codon Mutations in Forty Saccharomyces cerevisiae Strains: Implications for [PSI+] Prion- Mediated Phenotypes

The yeast prion [PSI+] has been implicated in the generation of novel phenotypes by a mechanism involving a reduction in translation fidelity causing readthrough of naturally occurring stop codons. Some [PSI+] associated phenotypes may also be generated due to readthrough of inactivating stop codon mutations (ISCMs). Using next generation sequencing we have sequenced the genomes of two Saccharomyces cerevisiae strains that are commonly used for the study of the yeast [PSI+] prion. We have identified approximately 26,000 and 6,500 single nucleotide polymorphisms (SNPs) in strains 74-D694 and G600 respectively, compared to reference strain S288C. In addition to SNPs that produce non-synonymous amino acid changes we have also identified a number of SNPs that cause potential ISCMs in these strains, one of which we show is associated with a [PSI+]-dependent stress resistance phenotype in strain G600. We identified twenty-two potential ISCMs in strain 74-D694, present in genes involved in a variety of cellular processes including nitrogen metabolism, signal transduction and oxidative stress response. The presence of ISCMs in a subset of these genes provides possible explanations for previously identified [PSI+]-associated phenotypes in this strain. A comparison of ISCMs in strains G600 and 74-D694 with S. cerevisiae strains sequenced as part of the Saccharomyces Genome Resequencing Project (SGRP) shows much variation in the generation of strain-specific ISCMs and suggests this process is possible under complex genetic control. Additionally we have identified a major difference in the abilities of strains G600 and 74-D694 to grow at elevated temperatures. However, this difference appears unrelated to novel SNPs identified in strain 74-D694 present in proteins involved in the heat shock response, but may be attributed to other SNP differences in genes previously identified as playing a role in high temperature growth