31,822 research outputs found

    Evidence of Klein tunneling in graphene p-n junctions

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    Transport through potential barriers in graphene is investigated using a set of metallic gates capacitively coupled to graphene to modulate the potential landscape. When a gate-induced potential step is steep enough, disorder becomes less important and the resistance across the step is in quantitative agreement with predictions of Klein tunneling of Dirac fermions up to a small correction. We also perform magnetoresistance measurements at low magnetic fields and compare them to recent predictions.Comment: Major changes made: 1) Taking into account properly the contribution of the resistance of monopolar junctions to the odd part of the resistance. To better present the results we use a fitting parameter for the amplitude of screening in graphene. 2) Wrong data for the diffusive model in figures 3, 9 and 10 was plotted in former version. 3) Figure 5 moved to EPAP

    The nature of the red disk-like galaxies at high redshift: dust attenuation and intrinsically red stellar populations

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    We investigate which conditions of dust attenuation and stellar populations allow models of dusty, continuously star-forming, bulge-less disk galaxies at 0.8<z<3.2 to meet the different colour selection criteria of high-z ``red'' galaxies (e.g. Rc-K>5.3, Ic-K>4, J-K>2.3). As a main novelty, we use stellar population models that include the thermally pulsating Asymptotic Giant Branch (TP-AGB) phase of stellar evolution. The star formation rate of the models declines exponentially as a function of time, the e-folding time being longer than 3 Gyr. In addition, we use calculations of radiative transfer of the stellar and scattered radiation through different dusty interstellar media in order to explore the wide parameter space of dust attenuation. We find that synthetic disks can exhibit red optical/near-infrared colours because of reddening by dust, but only if they have been forming stars for at least about 1 Gyr. Extremely few models barely exhibit Rc-K>5.3, if the inclination i=90 deg and if the opacity 2*tauV>6. Hence, Rc-K-selected galaxies at 1<z<2 most probably are either systems with an old, passively evolving bulge or starbursts. Synthetic disks at 1<z<2 exhibit 4<Ic-K<4.8, if they are seen edge on (i.e. at i about 90 deg) and if 2*tauV>0.5. This explains the large fraction of observed, edge-on disk-like galaxies with Ks4. Finally, models with 2<z<3.2 exhibit 2.3<J-K<3, with no bias towards i about 90 deg and for a large range in opacity (e.g. 2*tauV>1 for i about 70 deg). In conclusion, red disk-like galaxies at 0.8<z<3.2 may not necessarily be dustier than nearby disk galaxies (with 0.5<2*tauV<2) and/or much older than about 1 Gyr. This result is due both to a realistic description of dust attenuation and to the emission contribution by TP-AGB stars... (Abridged)Comment: 16 pages, 8 ps figures, accepted for publication in MNRA

    Specific Adhesion of Membranes Simultaneously Supports Dual Heterogeneities in Lipids and Proteins

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    Membrane adhesion is a vital component of many biological processes. Heterogeneities in lipid and protein composition are often associated with the adhesion site. These heterogeneities are thought to play functional roles in facilitating signalling. Here we experimentally examine this phenomenon using model membranes made of a mixture of lipids that is near a phase boundary at room temperature. Non-adherent model membranes are in a well-mixed, disordered-fluid lipid phase indicated by homogeneous distribution of a fluorescent dye that is a marker for the fluid-disordered (Ld) phase. We specifically adhere membranes to a flat substrate bilayer using biotin–avidin binding. Adhesion produces two types of coexisting heterogeneities: an ordered lipid phase that excludes binding proteins and the fluorescent membrane dye, and a disordered lipid phase that is enriched in both binding proteins and membrane dye compared with the non-adhered portion of the same membrane. Thus, a single type of adhesion interaction (biotin–avidin binding), in an initially-homogeneous system, simultaneously stabilizes both ordered-phase and disordered-phase heterogeneities that are compositionally distinct from the non-adhered portion of the vesicle. These heterogeneities are long-lived and unchanged upon increased temperature.This work was funded by start-up funds from The University of Texas at Austin (UT Austin) to VDG. MR was supported in part by undergraduate research fellowships from UT Austin. We are grateful to Professor Jeanne Stachowiak (Biomedical Engineering, UT Austin) for helpful conversations about membrane formation and to her and her group for technical assistance. We thank Professor Ernst-Ludwig Florin (Physics, UT Austin) for the extruder and for cover glasses. We thank Professor Lauren Ehrlich (Molecular Biosciences, UT Austin) for helpful conversations about the immune synapse.Center for Nonlinear Dynamic

    Discovery of Blue Luminescence in the Red Rectangle: Possible Fluorescence from Neutral Polycyclic Aromatic Hydrocarbon Molecules?

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    Here we report our discovery of a band of blue luminescence (BL) in the Red Rectangle (RR) nebula. This enigmatic proto-planetary nebula is also one of the brightest known sources of extended red emission as well as of unidentified infra-red (UIR) band emissions. The spectrum of this newly discovered BL is most likely fluorescence from small neutral polycyclic aromatic hydrocarbon (PAH) molecules. PAH molecules are thought to be widely present in many interstellar and circumstellar environments in our galaxy as well as in other galaxies, and are considered likely carriers of the UIR-band emission. However, no specific PAH molecule has yet been identified in a source outside the solar system, as the set of mid-infra-red emission features attributed to these molecules between the wavelengths of 3.3 micron and 16.4 micron is largely insensitive to molecular sizes. In contrast, near-UV/blue fluorescence of PAHs is more specific as to size, structure, and charge state of a PAH molecule. If the carriers of this near-UV/blue fluorescence are PAHs, they are most likely neutral PAH molecules consisting of 3-4 aromatic rings such as anthracene (C14H10) and pyrene (C16H10). These small PAHs would then be the largest molecules specifically identified in the interstellar medium.Comment: 4 pages, 4 figures, Accepted for publication in ApJL (LaTeX, uses emulateapj.sty

    Physiological Effects of Chronic Copper Exposure to Rainbow Trout (\u3cem\u3eOncorhynchus Mykiss\u3c/em\u3e) in Hard and Soft Water: Evaluation of Chronic Indicators

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    Effects of chronic copper exposure on a suite of indicators were examined: acute toxicity, acclimation, growth, sprint performance, whole-body electrolytes, tissue residues, and gill copper binding characteristics. Juvenile rainbow trout were exposed for 30 d to waterborne copper in hard water (hardness = 120 ÎĽg/L as CaCO3, pH = 8.0, Cu = 20 and 60 ÎĽg/L) and soft water (hardness = 20 ÎĽg/L as CaCO3, pH = 7.2, Cu = 1 and 2 ÎĽg/L). Significant acclimation to the metal occurred only in fish exposed to 60 mg/L, as seen by an approx. twofold increase in 96-h LC50 (153 vs 91 ÎĽg Cu/L). Chronic copper exposure had little or no effect on survival, growth, or swimming performance in either water hardness, nor was there any initial whole-body electrolyte loss (Na+ and Cl-). The present data suggest that the availability of food (3% wet body weight/day, distributed as three 1% meals) prevented growth inhibition and initial ion losses that usually result from Cu exposure. Elevated metal burdens in the gills and livers of exposed fish were measures of chronic copper exposure but not of effect. Initial gill binding experiments revealed the necessity of using radiolabeled Cu (64Cu) to detect newly accumulated Cu against gill background levels. Using this method, we verified the presence of saturable Cu-binding sites in the gills of juvenile rainbow trout and were able to make estimates of copperbinding affinity (log Kgill=Cu) and capacity (Bmax). Furthermore, we showed that both chronic exposure to Cu and to low water calcium had important effects on the Cu-binding characteristics of the gills

    A community pharmacy weight management programme: an evaluation of effectiveness

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    &lt;p&gt;Background: Community pharmacies may offer an accessible way of delivering weight-management programmes but there have been few trials that use clinically significant weight loss outcomes, objective measures of weight and follow-up to 12 months. We aimed to evaluate weight change among patients who used the Counterweight weight management programme delivered by community pharmacies.&lt;/p&gt; &lt;p&gt;Methods: The Counterweight Programme was introduced into community pharmacies in Fife, Scotland in 2009 for patients with a BMI ≥ 30 kg/m2 or a BMI ≥ 28 kg/m2 with a co-morbidity in localities in which Counterweight was not available at GP practices. The aim was to achieve an energy deficit of 500-600 kcal per day. Counterweight specialist dietitians delivered training, support and patient information materials to community pharmacies. Patient weight was measured by pharmacy staff at each weight management session. Weight data recorded at each weight management session were used to estimate weight change and attendance at 3, 6 and 12 months.&lt;/p&gt; &lt;p&gt;Results: Between March 2009 and July 2012, 458 patients were enrolled by the community pharmacies. Three-quarters of patients were women, mean age was 54 (SD 7.4) years and mean BMI 36.1 (SD 5.9) kg/m2. Of 314 patients enrolled for at least 12 months, 32 (10.2% on an intention to treat basis) had achieved the target weight loss of ≥5%; this was 41.6% of those who attended at 12 months representing a mean weight loss of 4.1 kg. Using Last Observation Carried Forward, 15.9% achieved the target weight loss within 12 months of enrolling. There was no significant effect of sex, baseline BMI or age on weight loss.&lt;/p&gt; &lt;p&gt;Conclusions: The Counterweight pharmacy programme has a similar effectiveness to other primary care based weight management programmes and should be considered as part of a range of services available to a community to manage overweight and obesity.&lt;/p&gt
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