Intelligent virtual doctor system

There are essentially only two problems, which plague the development of healthcare in third world countries. The first is a shortage of medical expertise and the second is the difficulty to teach rural communities. To solve these problems, most countries would setup clinics manned by nurses who in turn will consult doctors through phone calls or periodic visits. As such, we propose a new system in which the nurses or the patients themselves seek medical advise through a user-friendly system built on natural speech technology developed on field of telemedicine

Towards a more natural and intelligent interface with embodied conversation agent

Conversational agent also known as chatterbots are computer programs which are designed to converse like a human as much as their intelligent allows. In many ways, they are the embodiment of Turing's vision. The ability for computers to converse with human users using natural language would arguably increase their usefulness. Recent advances in Natural Language Processing (NLP) and Artificial Intelligence (AI) in general have advances this field in realizing the vision of a more humanoid interactive system. This paper presents and discusses the use of embodied conversation agent (ECA) for the imitation games. This paper also presents the technical design of our ECA and its performance. In the interactive media industry, it can also been observed that the ECA are getting popular

An embodied conversational agent for intelligent web interaction on pandemic crisis communication

In times of crisis, an effective communication mechanism is paramount in providing accurate and timely information to the community. In this paper we study the use of an intelligent embodied conversational agent (EGA) as the front end interface with the public for a Crisis Communication Network Portal (CCNet). The proposed system, CCNet, is an integration of the intelligent conversation agent, AINI, and an Automated Knowledge Extraction Agent (AKEA). AKEA retrieves first hand information from relevant sources such as government departments and news channels. In this paper, we compare the interaction of AINI against two popular search engines, two question answering systems and two conversational systems

A Review On Automatic Text Summarization Approaches

It has been more than 50 years since the initial investigation on automatic text summarization was started.Various techniques have been successfully used to extract the important contents from text document to represent document summary.In this study,we review some of the studies that have been conducted in this still-developing research area.It covers the basics of text summarization,the types of summarization,the methods that have been used and some areas in which text summarization has been applied.Furthermore,this paper also reviews the significant efforts which have been put in studies concerning sentence extraction,domain specific summarization and multi document summarization and provides the theoretical explanation and the fundamental concepts related to it.In addition,the advantages and limitations concerning the approaches commonly used for text summarization are also highlighted in this study

An improved deepfake detection method based on CNNS

Today's image generation technology can generate high-quality face images, and it isn't easy to recognize the authenticity of the generated images through human eyes. This study aims to improve deepfake detection, a face swapping forgery, by absorbing the advantages of deep learning technologies. This study generates a unified and enhanced data set from multiple sources using spatial enhancement technology to solve the problem of poor detection performance on cross-data sets. Taking the advantages of Inception and ResNet networks, new deepfake detection architecture composed of 20 network layers is proposed as the deepfake detection model. To further improve the proposed model, hyperparameter values are optimized. The experiment result shows that the proposed network significantly enhanced over the mainstream methods, such as ResNeXt50, ResNet101, XceptionNet, and VGG19, in terms of accuracy, loss value, AUC, numbers of parameters, and FLOPs. Overall, the methods introduced in this study can help to expand the data set, better detect deepfake contents, and effectively optimize network model

Prevalence of DDC genotypes in patients with aromatic L-amino acid decarboxylase (AADC) deficiency and in silico prediction of structural protein changes

Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare autosomal recessive genetic disorder affecting the biosynthesis of dopamine, a precursor of both norepinephrine and epinephrine, and serotonin. Diagnosis is based on the analysis of CSF or plasma metabolites, AADC activity in plasma and genetic testing for variants in the DDC gene. The exact prevalence of AADC deficiency, the number of patients, and the variant and genotype prevalence are not known. Here, we present the DDC variant (n = 143) and genotype (n = 151) prevalence of 348 patients with AADC deficiency, 121 of whom were previously not reported. In addition, we report 26 new DDC variants, classify them according to the ACMG/AMP/ACGS recommendations for pathogenicity and score them based on the predicted structural effect. The splice variant c.714+4A>T, with a founder effect in Taiwan and China, was the most common variant (allele frequency = 32.4%), and c.[714+4A>T];[714+4A>T] was the most common genotype (genotype frequency = 21.3%). Approximately 90% of genotypes had variants classified as pathogenic or likely pathogenic, while 7% had one VUS allele and 3% had two VUS alleles. Only one benign variant was reported. Homozygous and compound heterozygous genotypes were interpreted in terms of AADC protein and categorized as: i) devoid of full-length AADC, ii) bearing one type of AADC homodimeric variant or iii) producing an AADC protein population composed of two homodimeric and one heterodimeric variant. Based on structural features, a score was attributed for all homodimers, and a tentative prediction was advanced for the heterodimer. Almost all AADC protein variants were pathogenic or likely pathogenic

Prevalence of DDC genotypes in patients with aromatic L-amino acid decarboxylase (AADC) deficiency and in silico prediction of structural protein changes

Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare autosomal recessive genetic disorder affecting the biosynthesis of dopamine, a precursor of both norepinephrine and epinephrine, and serotonin. Diagnosis is based on the analysis of CSF or plasma metabolites, AADC activity in plasma and genetic testing for variants in the DDC gene. The exact prevalence of AADC deficiency, the number of patients, and the variant and genotype prevalence are not known. Here, we present the DDC variant (n = 143) and genotype (n = 151) prevalence of 348 patients with AADC deficiency, 121 of whom were previously not reported. In addition, we report 26 new DDC variants, classify them according to the ACMG/AMP/ACGS recommendations for pathogenicity and score them based on the predicted structural effect. The splice variant c.714+4A>T, with a founder effect in Taiwan and China, was the most common variant (allele frequency = 32.4%), and c.[714+4A>T];[714+4A>T] was the most common genotype (genotype frequency = 21.3%). Approximately 90% of genotypes had variants classified as pathogenic or likely pathogenic, while 7% had one VUS allele and 3% had two VUS alleles. Only one benign variant was reported. Homozygous and compound heterozygous genotypes were interpreted in terms of AADC protein and categorized as: i) devoid of full-length AADC, ii) bearing one type of AADC homodimeric variant or iii) producing an AADC protein population composed of two homodimeric and one heterodimeric variant. Based on structural features, a score was attributed for all homodimers, and a tentative prediction was advanced for the heterodimer. Almost all AADC protein variants were pathogenic or likely pathogenic