3 research outputs found
Tuberculosis Infection Could Mimic Malignant Lymphoma In F-18 FDG PET: A Case Report
Introduction: Lymphoma and tuberculosis in several cases share similar clinical features that are
difficult to differentiate. Lymphadenopathy, fever, malaise, weight loss, and respiratory
symptoms are clinical features that could be found in both lymphoma and tuberculosis. Positron
Emission Tomography/Computed Tomography Fluorodeoxyglucose (F-18 FDG PET) is a pivotal
modality for imaging patients with cancer. Several non-malignant diseases like tuberculosis
infection show high FDG uptake and lead to low specificity of F-18 FDG PET.
Case Presentation: This case report describes a 55-year-old male patient with a history of Diffuse
Large B-cell Lymphoma (DLBCL) who was suspected of having a recurrent disease. The patient
has had a 6-month remission period after 6 cycles of R-CHOP regimen chemotherapy. He denied
any known history of tuberculosis infection and HIV. F-18 FDG PET was performed to assess the
extent of suspected lymphoma recurrent disease. F-18 FDG PET demonstrated multiple
hypermetabolic bilateral neck region, mediastinum, and bilateral axilla lymphadenopathies.
There were also multiple high FDG uptakes in the liver, mesocolon, and bones. The patient was
suspected of having a lymphoma recurrent disease based on these findings. He underwent an
excisional biopsy in the neck and was found to have lymphadenitis granulomatous disease from
tuberculosis. Based on the histopathology finding, the patient received anti-tuberculosis drugs
for 12 months and showed relief of signs and symptoms. F-18 FDG PET for anti-tuberculosis
treatment evaluation revealed a complete metabolic response.
Conclusion: Tuberculosis should be one of the differential diagnoses when a lymphoma recurrent
disease is suspected. Clinical features, laboratory results, and imaging findings sometimes show
similarities between lymphoma and tuberculosis. Histopathology evaluation is mandatory to
confirm the diagnosis
Nutrition Management on Acute Pancreatitis
Pancreatitis is an inflammatory process in pancreas. Clinical manifestation of acute pancreatitis can be mild to severe. Mortality rate is high in severe acute pancreatitis. Etiology of acute pancreatitis generally remains obscured. Supportive management is important in acute pancreatitis. Nutrition is important part in acute pancreatitis. Patient should not be given enteral nutrition temporarily and meanwhile parenteral nutrition must provide sufficient amount of calories and nutritional requirements. Immune nutrition should also be considered. In mild acute pancreatitis, oral realimentation can be started in 3rd-7th day. In severe acute pancreatitis with prolonged fasting, gradual enteral nutrition via nasoenteral tube is recommended Keywords: nutrition, acute pancreatitis, enteral nutritio
Non Cirrhotic Portal Fibrosis
Diagnosis of non cirrhotic portal fibrosis was considered when the following criteria were fulfilled evidence of portal hypertension (oesophageal varices, hypersplenism, ascites, or increased hepatic venous pressure gradient), Doppler ultrasound showing patent portal and hepatic veins, and liver biopsy showing sign of cirrhosis. Non cirrhotic portal fibrosis clinically characterized by splenomegaly, anemia, portal hypertension, and histopathological examination portal tract showing fibrosis and sclerosis. Portal hypertension are most caused by a cirrhotic liver (85%), there are only a few reports on non cirrhotic portal hypertension, mostly in Japan and India. We reported a case of non cirrhotic portal fibrosis in young male. Â The clinical complications of portal hypertension are variceal bleeding and pancytopenia due to hypersplenism. Variceal band ligation and splenectomy were performed. The patient showed good clinical response. Â Keywords: portal hypertension, non cirrhotic portal fibrosis, young mal